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PURPOSE:This study aimed to: (i) present and characterize a phantom setup for validation of four-dimensional (4D) flow using particle imaging velocimetry (PIV) and planar laser-induced fluorescence (PLIF); (ii) validate 4D flow velocity measurements using PIV; and (iii) validate 4D flow vortex ring volume (VV) using PLIF.METHODS:A pulsatile pump and a tank with a 25-mm nozzle were constructed. PIV

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

We aimed to characterize the genomic profiles of adenocarcinomas in the gastroesophageal junction in relation to cancers in the esophagus and the stomach. Profiles of gains/losses as well as gene expression profiles were obtained from 27 gastroesophageal adenocarcinomas by means of 32k high-resolution array-based comparative genomic hybridization and 27k oligo gene expression arrays, and putative

The purpose of this thesis has been to study different dimensions of work and the political ”work-first” principal within strategies of social inclusion. The primary material of the analysis consists of two relevant and current documents concerning the strategy ”A coordinated and longterm strategy of roma inclusion 2012-2032” (author’s translation) of the Swedish government. I have applied two the

This book provides important insights into the domain of interactions between language and cognition, focusing on SPACE and expressions of SPACE. Both literal and metaphorical forms of expression are included. The research reported is carried out within the broad framework of Cognitive Linguistics, which encompasses a wide variety of empirical methods and research topics. Our approach to the const

Enumeration of circulating tumor cells (CTCs) predicts overall survival and treatment response in metastatic cancer, but as many commercialized assays isolate CTCs positive for epithelial cell markers alone, CTCs with little or no epithelial cell adhesion molecule (EpCAM) expression stay undetected. Therefore, CTC enrichment and isolation by label-free methods based on biophysical rather than bioc

Children can and should be encouraged to take an active part in their own care. With the introduction of online health care centers, where the main interaction is provided through digital consultations, the process for including the child must be revised. In addition to the medical and legal challenges, the digital interface needs to be designed so that the parent is encouraged to involve the chil

Erythroid cell commitment and differentiation proceed through activation of a lineage-restricted transcriptional network orchestrated by a group of well characterized genes. However, the minimal set of factors necessary for instructing red blood cell (RBC) development remains undefined. We employed a screen for transcription factors allowing direct lineage reprograming from fibroblasts to induced

Background: In Europe, residential care homes (RCHs) rather than hospitals are the most common care facilities for the older adult and the place where most deaths occur in this age group. There is a lack of knowledge regarding end-of-life (EOL) discussions and how they correlate with symptoms and symptom relief. Objective: The aim was to examine the correlation between EOL discussions and symptom

The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by consequences of simultaneous accumulation of a heterogeneous array of other hormones. Targets for spe

The trace element selenium is of essential importance for the synthesis of a set of redox active proteins. We investigated three complementary serum selenium status biomarkers in relation to overall survival and recurrence following diagnosis of primary invasive breast cancer in a large prospective cohort study. The Sweden Cancerome Analysis Network – Breast Initiative (SCAN-B) is a prospective po

Aims: Ischaemic coronary artery disease (CAD) remains the leading cause of mortality globally due to sudden death and heart failure (HF). Invasive coronary angiography (CAG) is the gold standard for evaluating the presence and severity of CAD. Our objective was to assess temporal trends in CAG utilization, patient characteristics, and prognosis in HF patients undergoing CAG at a national level. Me