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BackgroundRapid myelin water imaging (MWI) using a combined gradient and spin echo (GRASE) sequence can produce myelin specific metrics for the human brain. Spinal cord MWI could be similarly useful, but technical challenges have hindered routine application. GRASE rapid MWI was recently successfully implemented for imaging of healthy cervical spinal cord and may complement other advanced imaging
Fragmentation of habitat, for example by intensive agricultural practices, can be detrimental to local biodiversity. However, it often remains unclear whether such biodiversity declines are caused by loss of habitat area or increased fragmentation, and how habitat quality factors into it. In our study system, vegetated vineyards are typically small, and isolated from one another, potentially limit
This paper discusses the relationship between the Sustainable Development Goals (SDGs) and the long-standing human rights system of the United Nations. Thematically, these two modes of global governance strongly overlap. Several SDGs are in line with human rights obligations. At the same time, the SDGs and human rights are based on divergent logics and constructed very differently. After capturing
Since the turn of the millennium, the appointment of women judges has increased markedly in Africa and the Middle East, along with the social and political influence of courts. The expansion of judicial power worldwide raises important questions about who the judges are and what their role should be. The appointment of women to positions of judicial authority has increased, but this increase is on
Transportation equity is vital for the fulfillment of citizens’ activities. To make better decisions for transportation planning, it is appropriate to have a method to evaluate each mode and assign an equity score to it. This paper aims to propose a method to assess the level of equity using different transportation modes in each zone of a city. Here, the equity level takes into account on one sid
Selection leading to adaptation to interactions may generate rapid evolutionary feedbacks and drive diversification of species interactions. The challenge is to understand how the many traits of interacting species combine to shape local adaptation in ways directly or indirectly resulting in diversification. We used the well-studied interactions between Lithophragma plants (Saxifragaceae) and Grey
Introduction. The cure rate of early stage Hodgkin's lymphoma (HL) is excellent; investigating the late effects of treatment is thus important. Esophageal toxicity is a known side effect in patients receiving radiotherapy (RT) to the mediastinum, although little is known of this in HL survivors. This study investigates the dose to the esophagus in the treatment of early stage HL using different RT
We experimentally test theoretical predictions on equilibrium selection in a two-player coordination (investment) game. Through a minimal visual variation, our design prompts participants to play strategies whereby investing probability is either continuous or discontinuous in the payoff-relevant state. When participants use continuous strategies, average behavior is consistent with play in the ri
The combination of digital breast tomosynthesis (DBT) with other imaging modalities has been investigated in order to improve the detection and diagnosis of breast cancer. Mechanical Imaging (MI) measures the stress over the surface of the compressed breast, using a pressure sensor, during radiographic examination and its response has shown a correlation with the presence of malignant lesions. Thu
Extreme environmental conditions make soils of the hyper-arid Atacama Desert one of the most hostile habitats for life on the planet. During the short intervals of moisture availability that occur, it remains unresolved how soil microorganisms physiologically respond to such dramatic environmental changes. Therefore, we simulated a precipitation event – without (H2O) and with (H2O + C) labile carb
Food, hygiene, and safety are critical in healthcare institutions, especially those in which patients are vulnerable against diseases triggered by food prepared under improper conditions. In the United Kingdom, almost 400 healthcare institutions were found to need significant improvements to their food preparation standards (ITV News, 2016). Such institutions still rely on traditional pen and pape
Mitochondria are central organelles in the homeostasis of the cardiovascular system via the integration of several physiological processes, such as ATP generation via oxidative phosphorylation, synthesis/exchange of metabolites, calcium sequestration, reactive oxygen species (ROS) production/buffering and control of cellular survival/death. Mitochondrial impairment has been widely recognized as a
The technological evolution and widespread availability of wearables and handheld ECG devices capable of screening for atrial fibrillation (AF), and their promotion directly to consumers, has focused attention of health care professionals and patient organizations on consumer-led AF screening. In this Frontiers review, members of the AF-SCREEN International Collaboration provide a critical apprais
Bladder exstrophy is a rare congenital malformation leaving the urinary bladder open in the midline of the abdomen at birth. There is a clear genetic background with chromosome aberrations, but so far, no consistent findings apart from 22q11-duplications detected in about 2%–3% of all patients. Some genes are implicated like the LZTR1, ISL1, CELSR3, and the WNT3 genes, but most are not explained m
We consider a spectral problem associated with steady water waves of extreme form on the free surface of a rotational flow. It is proved that the spectrum of this problem contains arbitrary large negative eigenvalues and they are simple. Moreover, the asymptotics of such eigenvalues is obtained.
Aviation remains a problematic sector of the global economy in times of climate emergency. Grounded in the ideology of reconfiguration, we adopt a system transitions perspective to address high emissions leisure travel. Our focus falls on the marketing communications of airlines as a critical component in the prevailing sociotechnical regime. Thematic analysis of the e-mail marketing communication
The purpose of this article is to develop more fully the notion of the international identity of the European Union (EU) in world politics. We will attempt to balance our previous focus of work on the "active dimension' of the EU' s attempts to "assert its identity on the international scene'; by looking at the "reflexive dimension'; of the EU's international identity from a more sociological pers
Euthymios the Athonite (or the Iberian; ca. 955–1028) is a well-known translator of Greek hagiographical and patristic texts into Georgian. He also made reverse translations, not least the story of Barlaam and Ioasaph, from Georgian into Greek. An array of Greek texts at his disposal helped him turn the story into a recognizable Byzantine text, free of dogmatic problems. Based on the results by Gr
The coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a serious global healthcare crisis, so there is an emergence of identifying efficacious therapeutic options. In a setting where there is an unavailability of definitive medication along with the constant eruption of vaccine-related controversies, the drug-repositioning appr
