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Dihydroorotate dehydrogenase (DHODH, EC 1.3.99.11), the fourth enzyme of pyrimidine de novo synthesis, is an integral flavoprotein of the inner mitchondrial membrane and is functionally connected to the respiratory chain. Here, experiments have been directed toward determining the roles of the N-terminal sequence motifs both in enzymatic properties of insect DHODH produced in vitro and the in vivo
The European Green Deal states that greenhouse gas (GHG) emissions should be reduced by at least 50% by 2030, and that there should be no net GHG emissions by 2050. The energy sector is a key in this transformation, and energy communities can as accelerators of transitionsKey findings:•Future scenarios outline a decentralized energy system in which smaller generation units have become more economi
Sweden passed legislation to achieve a target of net zero greenhouse gas emissions by the end of 2045. The Energy Performance of Building Directive further obliged European countries to ensure zero-energy building codes and improve the quality of indoor environments when buildings are renovated, as approximately 40% of total greenhouse gas emissions in Sweden are produced while heating buildings.
Freshwater scarcity is a vital societal challenge related to climate change, population pressure, and agricultural and industrial demands. Therefore, sustainable desalination/purification of salty/contaminated water for human uses is particularly relevant. Membrane distillation is an emerging hybrid thermal-membrane technology with the potential to overcome the drawbacks of conventional desalinati
Human herpesvirus (HHV)-6A or HHV-6B involvement in multiple sclerosis (MS) etiology has remained controversial mainly due to the lack of serological methods that can distinguish the two viruses. A novel multiplex serological assay measuring IgG reactivity against the immediate-early protein 1 from HHV-6A (IE1A) and HHV-6B (IE1B) was used in a MS cohort (8,742 persons with MS and 7,215 matched con
This paper investigates whether executive boards consider firm-specific inefficiencies when they change CEOs in the Swedish electricity distribution sector. Firm-level inefficiencies are calculated using data from all Swedish electricity distributors from 2001 to 2022 and a data envelopment analysis (DEA) approach. DEA has advantages over standard financial key performance indicators since it cont
We use first-principle density functional theory (DFT) to predict properties for semicrystalline polyvinyl fluoride (PVF) and compare with polyvinylidiene fluoride. We note that the crystalline regions of PVF are complex in the sense that we lack a complete experimental characterization of the detailed atomic organization. We therefore turn to DFT to predict both the structure and associated mater
The European Union has committed to achieving climate neutrality by the year 2050, with Sweden setting an even more ambitious target of reaching this milestone by 2045. A subgroup comprising 23 pioneering Swedish municipalities, collectively representing 40% of the country's population, aims to attain climate neutrality by 2030. Globally, buildings and construction sector contribute nearly 40% of
Energy is essential for the sustenance of life. The energy and economy of any nation are interlinked—energy demand is generally proportional to the economic growth of the nation. In the present era, renewable energy (RE) is the primary area of interest to save fossil fuels, achieve sustainability, and reducing carbon emissions, as well as other gases in the atmosphere that create climatic problems
The exponential growth of converging technologies, including augmented reality, autonomous vehicles, machine-to-machine and machine-to-human interactions, biomedical and environmental sensory systems, and artificial intelligence, is driving the need for robust infrastructural systems capable of handling vast data volumes between end users and service providers. This demand has prompted a significa
The EU's Clean Energy Package introduced renewable and citizen energy communities (RECs/CECs) to strengthen citizen participation in electricity markets. Nordic countries, however, have long-standing traditions of community-based energy provision, including district heating cooperatives, small hydropower schemes, and wind cooperatives. This article examines how nationally embedded energy models in
Exempel på foldrar och broschyrer från Lunds universitet Rubrik UNDERTEXT Foldrar och broschyrer EXEMPEL MED OCH UTAN GRID Framsida broschyr, A4. Framsida broschyr, A5. Forskningsstrategi 2017–2021 | LUNDS UNIVERSITET Forskningsstrategi 2017–2021 | LUNDS UNIVERSITET Humaniora & teologi LUNDS UNIVERSITET | UTBILDNINGSKATALOG | 2019/2020 Humaniora & teologi LUNDS UNIVERSITET | UTBILDNINGSKATALOG | 2
https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/foldrar-o-broschyrer.pdf - 2026-07-13
The Kruppel-like protein ZNF224 is a co-factor of the Wilms' tumor 1 protein, WT1. We have previously shown that ZNF224 exerts a specific proapoptotic role in chronic myelogenous leukemia (CML) K562 cells and contributes to cytosine arabinoside-induced apoptosis, by modulating WT1-dependent transcription of apoptotic genes. Here we demonstrate that ZNF224 gene expression is down-regulated both in
Cocaine- and amphetamine-regulated transcript (CART) is a regulatory peptide expressed in the nervous system and in endocrine cells, e.g. in pancreatic islets. CART deficient mice exhibit islet dysfunction, impaired insulin secretion and increased body weight. A mutation in the CART gene in humans is associated with reduced metabolic rate, obesity and diabetes. Furthermore, CART is upregulated in
Machining-based deformation processing is used to produce metal foil and flat wire (strip) with suitable properties and quality for electrical power and renewable energy applications. In contrast to conventional multistage rolling, the strip is produced in a single-step and with much less process energy. Examples are presented from metal systems of varied workability, and strip product scale in te
