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Mouse embryonic stem cell (mESC) lines were derived by crossing heterozygous transgenic (tg) mice expressing green fluorescent protein (GFP) under the control of the rat tyrosine hydroxylase (TH) promoter, with homozygous alpha-synuclein (aSYN) mice expressing human mutant SNCAA53T under the control of the mouse Prion promoter (MoPrP), or wildtype (WT) mice. The expression of GFP and human aSYN wa

European Resuscitation Council (ERC) issued updated guidelines for postresuscitation care in 2015. This paper provides updated Swedish recommendations for neurological prognostication of patients remaining unconscious after cardiac arrest (CA). The prognostication should be based on independent methods; clinical and neurophysiological examinations, imaging and biomarkers. It should not be performe

Working within the Langevin framework of nuclear shape dynamics, we study the dependence of the evolution on the degree of excitation. As the excitation energy of the fissioning system is increased, the pairing correlations and the shell effects diminish and the effective potential-energy surface becomes ever more liquid-drop like. This feature can be included in the treatment in a formally well-f

Background: Treatment of common bile duct (CBD) stones after Roux-en-Y gastric bypass (RYGB) poses a particular challenge given the altered anatomy and inability to perform a standard endoscopic retrograde cholangiogram (ERC). The optimal treatment strategy for intraoperatively encountered CBD stones in post-RYGB patients has not been established. Objectives: To compare outcomes following laparosc

A stochastic hierarchical model for the evolution of low grade gliomas is proposed. Starting with the description of cell motion using a piecewise diffusion Markov process (PDifMP) at the cellular level, we derive an equation for the density of the transition probability of this Markov process based on the generalised Fokker–Planck equation. Then, a macroscopic model is derived via parabolic limit

Quinoa (Chenopodium quinoa Willd.) has gained recent popularity mainly due to its attractive nutritional profile and its ability to grow under extreme conditions such as salinity, acidity, drought, flooding, and frost as well as the functionality of its component. Starch is the main component of quinoa grain which constitutes up to 60% of the dry grain and plays a crucial role in the functional pr

How can cities and communities around the world become more sustainable? What can we do as researchers to help them? As we move through the twenty-first century, these questions assume ever-greater importance. Many of the quickest wins for human and planetary health involve reimagining and reconfiguring cities. Activities that generate negative impacts like air pollution and poor health are concen

Många arbetsgivare känner inte till att de redan idag använder sig av artificiell intelligens, AI, eller annat automatiserat beslutsfattande. Det visar den rapport om AI och risker för diskriminering i arbetslivet som Diskrimineringsombudsmannen, DO, publicerar idag. Att arbetsgivare har denna kunskap är avgörande för att arbeta förebyggande för att motverka diskriminering vid tillämpning av tekni

This chapter begins by providing a general contextualisation of hate speech and the controversies around it. It then asks two questions: Is Holocaust denial a form of hate speech? If the answer is positive, should Holocaust denial be banned?The second section explains what is hate speech. The third section is concerned with the relationship between hate speech and hate crime. The fourth section di

The Centre Party is one of the oldest political parties in Sweden that is still represented in the Swedish parliament. They are also currently the only party that originally developed from interest groups in the countryside. This paper focuses on the Centre Party’s church politics. The purpose of the paper is to find out how this agrarian party has shifted its’ policies regarding their church poli

”Vårt samhälle blir alltmer sårbart” är säkert en formulering du känner igen. Faktum är att vårt samhälle är fullt av risker, stora som små, och för att minska dessa gör varje kommun en risk- och sårbarhetsanalys. Analysen ska bland annat hjälpa politiker att ta beslut om åtgärder som kan minska samhällets risker och i denna artikel ställer vi oss frågan om detta faktiskt händer? Risk definieras iThis thesis examines to what extent the comprehensive municipal risk and vulnerability analysis work as a basis for decision-making concerning risk and vulnerability reducing measures in eight Swedish municipalities. An additional objective is to identify mechanisms influencing the decision-making process regarding such measures. In order to meet these objectives an interview study was conducted i

Förenta Nationernas Ekonomiska Kommission för Europas Konvention om tillgång till information, allmänhetens deltagande i beslutsprocesser och tillgång till rättslig prövning i miljöfrågor (Århuskonventionen) anses vara det essentiella rättsligt bindande instrumentet för skyddet av allmänhetens miljörelaterade rättigheter. Konventionen bygger på uppfattningen att processuella rättigheter i samband The United Nation Economic Commission for Europe’s Convention on access to information, public participation in decision-making, access to justice in environmental matters (hereafter the Aarhus Convention) is considered to be the main legally binding instrument protecting the public’s environmental rights. It is based on the idea that procedural rights relating to environmental matters should cont

Tidigare forskning har visat att patienter inom psykiatrin är föremål för kränkande behandling och oetiskt bemötande från personalen, där stigmatisering av psykisk sjukdom ses som en bidragande faktor. Föreliggande studie ämnade att undersöka bemötandebrister inom den svenska vuxenpsykiatrin. Syftet var att identifiera riskfaktorer för kränkande behandling och olika former av oetiskt bemötande av Previous research has shown how patients in psychiatry are subjected to abusive and unethical treatment by staff, where stigmatization of mental illness is seen as a contributing factor. The present study aimed to investigate treatment deficiencies in Swedish adult psychiatry. The purpose was to identify risk factors for treatment deficiencies described as abusive and unethical treatment of patien

Uppsatsen undersöker lämpligheten att införa storskalig miljöförstöring, i form av ekocid, som ett femte internationellt brott i Romstadgan för internationella brottmålsdomstolen som antogs i Rom 1998. Undersökningen görs i förhållande till Romstadgans syfte och målsättning och i förhållande till de brott som utgör kärnan av Romstadgan. Kärnbrotten utgörs av folkmord, brott mot mänskligheten, krigThis essay examines the possibility to make environmental destruction an international crime by including ecocide as a fifth crime against peace in the Rome Statute of the International Criminal Court adopted in Rome in 1998. The issue is examinated in relation to the purpose and objective of the Statue and in relations to the core crimes. The core crimes; crime of genocide, crimes against humanit

Med anledning av klimatkrisen har EU-kommissionen presenterat En ny handlingsplan för den cirkulära ekonomin – För ett renare och mer konkur-rens-kraftigt Europa. Det huvudsakliga syftet med handlingsplanen är att skapa förutsättningar för att ställa om till ett klimatneutralt samhälle och att frikoppla ekonomisk tillväxt från resursanvändning. I handlingsplanen anges därför att förutsättningar föDue to the climate crisis, the European Commission has presented A new Circular Economy Action Plan – For a cleaner and more competitive Europe. The main purpose of the action plan is to create a framework for sustainable products to change into a climate neutral society and decoupling economic growth from resource use. The action plan therefore states that conditions for reuse and repair, among o