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Distinct GATA6- and laminin-dependent mechanisms regulate endodermal and ectodermal embryonic stem cell fates

This study investigates the establishment of alternative cell fates during embryoid body differentiation when ES cells diverge into two epithelia simulating the pre-gastrulation endoderm and ectoderm. We report that endoderm differentiation and endoderm-specitic gene expression, such as expression of laminin 1 subunits, is controlled by GATA6 induced by FGF. Subsequently, differentiation of the no

Tracing Sustainability in the Long Run : Genuine Savings Estimates 1850 - 2018

We introduce a new database of historical Genuine Savings (GS), an indicator of sustainable development promoted by the World Bank and widely used in contemporary economic research. GS derives from the theoretical work on wealth accounting, and addresses shortcomings in conventional metrics of economic development by incorporating broader measures of saving and investment, including human capital

What Are They Seeking Next?

This thesis investigates the dynamics between firms’ shifting motives for engaging in foreign direct investments (FDIs) and the experiential knowledge acquired from increased experience and establishment in foreign markets. An embedded case study was performed on the multinational company Duni Group, drawing upon insights from semi-structured interviews with representatives from the case company.

“Vi måste släcka bränder” Socionomers beskrivningar av orsakerna bakom ungdomskriminalitet och deras reflektioner avseende det förebyggande arbetet

Youth delinquency is an international phenomenon that has an impact on different aspects of society. This study aimed to understand how social workers describe the causes of youth delinquency and their reflections on how they conduct the preventative work at social services. The chosen method was semi-structured interviews with six social workers in Skåne, all with a minimum of one year of working

Kriminalisering - ett effektivt kartellbekämpningsmedel?

Syftet med uppsatsen är att utreda den föreslagna kriminaliseringens effekt på Sveriges nuvarande eftergiftsprogram samt undersöka dess effektivitet trots avsaknad av ett kronvittnesförfarande. Vidare avser uppsatsen att undersöka om kriminaliseringens effekter kan påverkas. För att utröna kriminaliseringens effekter har VD: n få en central roll i uppsatsens modell, då det endast är han som berörs

Current-voltage analysis : Lessons learned from hysteresis

Progress in the power conversion efficiency of solar cells based on metal-halide perovskite semiconductors has been astonishing for the past years. During their development, transient effects have been observed that gave rise to an uncertainty associated with the determination of device performance from current density-voltage (J-V) measurements. This effect becomes visible in a dependence of the

Drivers of unhygienic desludging practices in unplanned settlements of dar es Salaam, Tanzania

Desludging is considered a key step in urban sanitation improvement. Nevertheless, in most urban unplanned settlements, desludging is performed in an unhygienic manner, risking public health. This study used a combination of qualitative and quantitative methods to analyse the underlying factors for unhygienic desludging in three urban unplanned settlements of Dar es Salaam, Tanzania. Factors for u

Mapping NPP for a coniferous forest in southern sweden using data from Terra/MODIS

Net primary production (NPP) is modeled for a coniferous forest in southern Sweden for 2001. The model is based on the light-use efficiency concept where NPP is calculated as a product of absorbed photosynthetically active radiation (APAR) and a light-use efficiency factor (ε). APAR is estimated from the fraction of APAR (FAPAR) multiplied with the daily total amount of incoming PAR. FAPAR is obta

Patterns and dietary determinants of essential and toxic elements in blood measured in mid-pregnancy : The Norwegian Environmental Biobank

Background: Inadequate stores or intakes of essential minerals in pregnancy, or too high exposure to both toxic and essential elements, can have adverse effects on mother and child. The main aims of this study were to 1) describe the concentrations and patterns of essential and toxic elements measured in maternal whole blood during pregnancy; 2) identify dietary, lifestyle and sociodemographic det

Non-coding RNAs to aid in neurological prognosis after cardiac arrest

Cardiovascular disease in general, and sudden cardiac death in particular, have an enormous socio-economic burden worldwide. Despite significant efforts to improve cardiopulmonary resuscitation, survival rates remain low. Moreover, patients who survive to hospital discharge have a high risk of developing severe physical or neurological symptoms. Being able to predict outcomes after resuscitation f

Studies of Volcanic Influence on Aerosols, Clouds and Climate

Popular Abstract in Swedish I atmosfären finns mikroskopiskt små luftburna partiklar. Till skillnad från makroskopiska partiklar sedimenterar dessa så kallade ’aerosol-partiklar’ så sakta att de följer med den omgivande luftens rörelser. I atmosfärens nedre luftlager (troposfären) avlägsnas aerosolpartiklarna från atmosfären av nederbörd. Partiklarna deponerar därför inom någon vecka. Ovanför tropThis thesis focuses on the influence of volcanism on the compositions of the aerosols in the upper troposphere (UT) and lowermost stratosphere (LMS), and their direct and indirect impact on climate. Aerosol data were obtained by aircraft-borne sampling, using the CARIBIC (Civil Aircraft for the Regular Investigation of the Atmosphere Based on an Instrument Container) platform, and laboratory-based

Threats to 5G group-based authentication

The fifth generation wireless system (5G) is expected to handle an unpredictable number of heterogeneous connected devices and to guarantee at least the same level of security provided by the contemporary wireless standards, including the Authentication and Key Agreement (AKA) protocol. The current AKA protocol has not been designed to efficiently support a very large number of devices. Hence, a n