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PURPOSE: Radiation to the bone and exposure to alkylating agents increases the risk of bone cancer among survivors of childhood cancer, but there is uncertainty regarding the risks of bone tissue radiation doses below 10 Gy and the dose-response relationship for specific types of chemotherapy.METHODS: Twelve European countries contributed 228 cases and 228 matched controls to a nested case-control

Children with generalized anxiety disorder (GAD) are often described by their parents or teachers as "little adults, " in part because of the seemingly adult-like themes that populate their child's worries; for example, the health of family members or family finances and concerns about performance. Younger children may experience more vague worries of "something" bad happening to themselves, famil

Research shows that a significant portion of the environmental impact from products is determined already in the design phase. Implementation of principles of Circular Economy (CE) in design practice has the potential to reduce waste and to encourage reuse of resources. Since designers are responsible for the design process, it is therefore relevant to investigate whether designers are properly eq

South Africa’s energy sector finds itself in a gridlock situation. The sector is controlled by the state-owned utility Eskom holding the monopoly on the generation and transmission of electricity, which is almost exclusively produced from domestically extracted coal. At the same time, the constitutional mandate enables municipalities to distribute and sell electricity generated by Eskom to local c

Muhammad 'Abduh (1849-1905) was one of the key thinkers and reformers of modern Islam who has influenced both liberal and fundamentalist Muslims today. 'Abdul-Baha (1844-1921) was the son of Baha'ullah (1817-1892), the founder of the Baha'i Faith; a new religion which began as a messianic movement in Shii Islam, before it departed from Islam. Oliver Scharbrodt offers an innovative and radically ne

China is using Buddhist narratives to promote its soft power in Sri Lanka – and bolster its image as a harmonious regional power.

BACKGROUND AND OBJECTIVES: The existence of social problems, crime, and a diminishing sense of community are acknowledged challenges to residents of deprived neighborhoods. In research on deprived neighborhoods in Sweden, the perspectives of young residents and adults of working age dominate. This study explores how older adults in deprived neighborhoods in Sweden experience crime and disorder, an

We provide a detailed map of the ages and metallicities of turn-off stars in the Milky Way disc based on data from GALAH DR3 and Gaia EDR3. From this map, we identify previously undetected features in the age-metallicity distribution of disc stars and interpret these results as indicating a three-phase formation history of the Milky Way. In the first phase, inner disc stars form along a single age

Radiological staging of rectal cancer dictates subsequent patienttreatment. In early-stage disease, local excision is associatedwith reduced morbidity, mortality, and costs, and maintainsbowel continuity compared with surgery, where the whole orpart of the rectum is resected1–3. Nearly 90 per cent of patientswith T1 rectal cancer have N0 disease and are therefore potentially curable with local res