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BACKGROUND: Amyloid-β positron emission tomography (PET) and cerebrospinal fluid (CSF) Aβ42 are considered interchangeable for clinical diagnosis of Alzheimer's disease. OBJECTIVE: To explore the clinical reasoning for requesting additional amyloid-β PET after performing CSF biomarkers. METHODS: We retrospectively identified 72 memory clinic patients who underwent amyloid-β PET after CSF biomarker

We show that tree-like resolution is not automatable in time no(log n) unless ETH is false. This implies that, under ETH, the algorithm given by Beame and Pitassi (FOCS 1996) that automates tree-like resolution in time no(log n) is optimal. We also provide a simpler proof of the result of Alekhnovich and Razborov (FOCS 2001) that unless the fixed parameter hierarchy collapses, tree-like resolution

This paper explores whether Ethiopia's rapid economic growth is transformative enough for the country to eventually catch up with high-income countries. It does so by exploring the change and continuity of four elements of social capability from 1950 to 2020: structural transformation, economic inclusion and the state's autonomy and accountability. It finds that Ethiopia's social capability modest

Background: The aggressive nature of breast cancers detected between planned mammographic screens, so-called interval cancers, remains elusive. Here, we aim to characterise underlying molecular features of interval cancer. Methods: From 672 patients with invasive breast cancer, we analysed gene expression differences between 90 ‘true’ interval cancer cases (i.e. women with low-dense breasts define

I present an empirically based argument for the plausibility of misrepresentation as posited by some higher-order theories of consciousness. The argument relies on the assumption that conscious states are generated by processes in the brain. The underlying idea is that if the brain generates conscious states then misrepresentation may occur. The reason for this is that brain states can be corrupte

The existence of a specific lysophospholipase in human pancreatic juice was evaluated. The proteins were separated by a series of chromatographic steps including Sephacryl S-200, cholate-Sepharose 4B, Sephadex G-100 and CM-Sephadex G-50. The enzyme activities against 1-palmitoyl lysolecithin (LL) as well as tributyrin (TB) and p-nitrophenyl butyrate (PNPB) were determined in all the fractions of t

In recent decades, we have witnessed an increasing use of projects and similar temporary modes of organising in the public sector of nations in Europe and around the world. While for some this is a welcome development which unlocks entrepreneurial zeal and renders public services more flexible and accountable, others argue that this seeks to depoliticise policy initiatives, rendering them increasi

Life is about timing.-Carl LewisThe understanding of autoimmune type 1 diabetes is increasing, and examining etiology separate from pathogenesis has become crucial. The components to explain type 1 diabetes development have been known for some time. The strong association with HLA has been researched for nearly 50 years. Genome-wide association studies added another 60+ non-HLA genetic factors wit

Title: Home is wherever your private equity firm takes you - A quantitative analysis comparing cross-border and domestic* transaction multiples in PE acquisitions of Nordic companies Seminar date: 30 May 2024 Course: NEKN02, Master Essay – Finance Programme, 15 ECTS Authors: Clarissa Nowak, Sofia Sjöholm Advisor: Jens Forssbaeck Keywords: Private Equity, Buyouts, Cross-Border, Valuation, Nord

Tillgången till rent dricksvatten varierar mellan olika delar i världen. Till exempel är grundvat- ten en stor resurs i Sverige där det står för 50 % av dricksvattnet, både artificiellt och naturligt bildat. Den siffran är endast 6 % i Moçambique och med tanke på att 47 % av populationen i landet saknar rent dricksvatten kan artifici- ell grundvattenbildning vara ett bra alternativ. Det finns olikThe amount of clean drinking water varies across different parts of the world. For example is groundwa- ter a big resource in Sweden and stands for 50% of the drinking water, both artificially and naturally recharged. The corresponding fraction is only about 6% in Mozambique and considering that 47% of the population in Mozam- bique lacks clean drinking water artificial recharge might be a good op

Every single State has its own rules: legal persons are created based on the domestic laws and States tax them according to their own tax laws. Thus, differences and imperfect legal relationships are inevitable at the international level. The existence of legal entities formed under diverse domestic laws which are not similar to each other leads to disparities and thus, to difficulties to have a c

This book is a key component of a PhD thesis derived from the artistic researchproject; How Little is Enough? and contains the essay Testimony of a Pilgrim andmanuscripts from the four performances that are central to the research project. Theentire PhD thesis is mediated through an on-line exposition on Research Catalogueusing mixed formats. The exposition encompasses the complete researchoutput

The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human malignancies. We previously employed retrotransposon capture sequencing (RC-seq) to analyze hepatocellular carcinoma (HCC) samples from patients infected with he

Mycobacterium tuberculosis is dependent on cysteine biosynthesis, and reduced sulfur compounds such as mycothiol synthesized from cysteine serve in first-line defense mechanisms against oxidative stress imposed by macrophages. Two biosynthetic routes to L-cysteine, each with its own specific cysteine synthase (CysK1 and CysM), have been described in M. tuberculosis, but the function of a third put

India has positioned itself as a leader in transitioning its energy sector to renewable sources, with ambitious targets and policies in place. Large-scale grid-integrated renewable energy plants have been identified as the most efficient option. Scholarly arguments differ regarding the impacts of renewables-led transitions, with some emphasizing positive environmental, economic, and social outcome