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Background and aims: Asthma is one of the most common respiratory diseases in the world. Research has shown that temporal increases in air pollution concentrations can aggravate asthma symptoms. The aim of this study was to assess whether individuals living in areas with higher air pollution concentrations responded differently to short-term temporal exposure to air pollution than those living in
Background: Stable atherosclerotic plaques are characterized by thick fibrous caps of smooth muscle cells, collagen, and macrocalcifications. Identifying factors of plaque stability is necessary to design drugs to prevent plaque rupture and symptoms. Osteomodulin, originally identified in bones, is expressed by bone synthesizing osteoblasts and involved in mineralization. In the present study, we
The energy transition is looking for new technologies to reduce CO2 emissions. One of the promising options is the dual fuel engine. In this concept, based on a diesel engine, a small pilot diesel injection is used to ignite a second fuel. This second fuel can be a low carbon or renewable high-octane fuel, that otherwise could not be applied in a diesel engine. Good results on emissions and effici
After a tank has been exposed to crash violence, or an external fire, it might, in some situations, be judged dangerous to move the vessel due to the risk of a sudden tank rupture. Therefore, Swedish rescue services have a long history of using rifles to penetrate and therefore depressurize the vessels. In this paper, some first steps on providing guidance on the selection of ammunition and requir
Despite being increasingly identified as main drivers of the global environmental emergency and existing inequalities, growth-driven economies have managed to perpetuate. Discursive practices are central to this perpetuation, strengthening the growth paradigm and its evolution towards ‘greener’ approaches, such as ‘green growth’. This work uses content analysis on presidential speeches to assess h
Degrowth scholars have been criticised for focusing too much on theory and macro-level of analysis, giving less attention to actual degrowth practices that happen at the local level. This thesis aims to make a contribution to this second field of degrowth research. Drawing on a practice theory approach, the objective of the study was to find whether degrowth practices and ideas have the potential
In the dual pursuit of expanding non-fossil fuel electricity capacity and becoming a ‘developed’ nation, India’s development trajectory drives the rapid expansion of large-scale solar photovoltaics (PV). In Jaisalmer, however, this expansion encounters complex socio-ecological landscapes marked by questions of (in)justice and uneven development. Drawing on energy geographies and energy justice, th
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive diseases and is characterized by high chemoresistance, leading to the lack of effective therapeutic approaches and grim prognosis. Despite increasing understanding of the mechanisms of chemoresistance in cancer and the role of ATP-binding cassette (ABC) transporters in this resistance, the therapeutic potential of their pharmaco
Forskare tar helhetsgrepp på boende för äldre – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Forskare tar helhetsgrepp på boende för äldre 2011-11-10 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Vigs Ängar äldreboende mellan Ystad och
https://www.vetenskaphalsa.se/boende-for-aldre-pa-vetenskaplig-grund/ - 2026-06-23
Prostate cancer is the most common malignancy of men in Western countries. Patients with advanced prostate cancer suffer from incurable bone metastases. Recent data indicate that interactions between prostate cancer cells, osteoblasts, osteoclasts and the bone matrix are essential in the formation of bone metastases. FGF-8 is widely overexpressed in prostate cancer. Recently, FGF-8 has been found
Antimicrobial peptides are important effectors of the innate immune system. These peptides belong to a multifunctional group of molecules that apart from their antibacterial activities also interact with mammalian cells and glycosaminoglycans and control chemotaxis, apoptosis, and angiogenesis. Here we demonstrate a novel antimicrobial activity of the heparin-binding and cell-binding domain 5 of h
Spidroins, the major silk proteins making up the spider's dragline silk, originate in two distinct tissue layers (A and B) in the spider's major ampullate gland. Formation of the complex thread from spidroins occurs in the lumen of the duct connected to the gland. Using pH-sensitive microelectrode probes, we showed that the spidroins traveling through the gland and duct experience a monotonic decr
The existence of a specific lysophospholipase in human pancreatic juice was evaluated. The proteins were separated by a series of chromatographic steps including Sephacryl S-200, cholate-Sepharose 4B, Sephadex G-100 and CM-Sephadex G-50. The enzyme activities against 1-palmitoyl lysolecithin (LL) as well as tributyrin (TB) and p-nitrophenyl butyrate (PNPB) were determined in all the fractions of t
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome associated with ribosomal gene mutations that lead to ribosomal insufficiency. DBA is characterized by anemia, congenital anomalies, and cancer predisposition. Treatment for DBA is associated with significant morbidity. Here, we report the identification of Nemo-like kinase (NLK) as a potential target for DBA therapy. To id
The role of mammalian Transient Receptor Potential Ankyrin 1 (TRPA1) as a mechanosensor is controversial. Here, we report that purified human TRPA1 (hTRPA1) with and without its N-terminal ankyrin repeat domain responded with pressure-dependent single-channel current activity when reconstituted into artificial lipid bilayers. The hTRPA1 activity was abolished by the thiol reducing agent TCEP. Thus
