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Depression is common during pregnancy, and a considerable proportion of pregnant women take antidepressants. Modern antidepressants (e.g. SSRIs) are fairly safe to use during pregnancy. Several physiological changes occur in the pregnant state, possibly affecting the pharmacokinetics of many drugs. Metabolism via CYP enzymes are important for the elimination of antidepressants. This metabolism may
1. Grassland is an important habitat for butterflies and many other pollinating insects. Over half of the 501 European butterflies use grasslands as one of their main habitats.2. The Grassland Butterfly Index has been adopted by the EU as a key measure of progress towards the target of halting biodiversity loss, restoring nature in agro-ecosystems and reversing the decline in pollinators by 2030,
Bcl-3 is a proto-oncogene and belongs to the inhibitor of κB (IκB) family and is known to be upregulated in numerous cancers. Bcl-3 can initiate transcription of different genes involved in cell survival and cell growth. Cell proliferation is achieved through binding of Bcl-3 to cyclin D1 promoter and facilitates the rapid transition from G1 to S phase. The aim of this thesis was to investigate th
BackgroundDeviating vital signs have been known to precede Serious Adverse Events (SAEs) like In-Hospital Cardiac Arrest (IHCA), unplanned Intensive Care Unit (ICU) admission or unexpected death for more than a decade but still the recognition of these deteriorating patients is poor.The British National Early Warning Score (NEWS) is a ‘‘track and trigger’’ scale designed to assess in-hospital pati
In this article, we introduce and demonstrate the concept-metaphor of broken data. In doing so, we advance critical discussions of digital data by accounting for how data might be in processes of decay, making, repair, re-making and growth, which are inextricable from the ongoing forms of creativity that stem from everyday contingencies and improvisatory human activity. We build and demonstrate ou
In contemporary Western theatre and actor’s training, there is a tension between different traditions in the actor’s work, concerning the bodily practices that are related to representation, construction of identities, authenticity and self-expression. One aspect of the actor’s methodical tradition – the openness to suffering and sacrificing oneself in the name of the arts – will be displayed and
