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Estramustine (EM), a complex between estradiol-17 beta and nornitrogen mustard, is commonly used in the treatment of prostatic cancer. The exact mechanism of action is unknown but has previously been considered to be mediated through non-DNA targets, specifically with the mitotic spindle, and to be related to the intact EM complex. In the present study, using different cell-systems (monocyte phago

Numerous post-conflict states in contemporary Africa are run by individuals who derive their origins from rebellion. Some take over or even improve existing state structures when seizing power, whereas others contribute to the fragmentation of the state. By comparing four insurgent movements that have managed to wrest state power; the NRA, the EPLF, the NPFL, and the USC, this study finds that soc

According to international treaty law as well as international customary law, threats of (armed) force are considered as one of the gravest violations of international law. Yet, threats of force frequently occur in international relations, often lacking condemnation by the international community. There are a number of reasons to why threats of force are sometimes passed by unconsidered by the int

Antidumping is a burning topic that has been lively debated lately. The usage of antidumping has enhanced during the past decade and affects the trade flow between countries. In this thesis antidumping procedures are investigated and effects on antidumping measures are analysed and discussed. All antidumping targeted footwear has been included in the investigation. The products originate from Chin

Public diplomacy, public relations, propaganda, and strategic narratives are all under the ‘umbrella’ of soft-power and nowadays’ international relations. Strategic narratives currently represent one of the most essential tools that political actors use to increase their influence on local and foreign audiences, gain public support, and lastly achieve their foreign policy objectives. This disser

Future wireless communications will rely on multiple-input multiple-output (MIMO) beamforming operating at millimeter wave (mmWave) frequency bands to deliver high data rates. To support flexible spatial processing and meet the demands of latency-critical applications, it is essential to use fully digital mmWave MIMO beamforming, which relies on accurate channel estimation. However, ensuring power

Invasive species are currently one of the main causes of biodiversity loss across the globe and recent research has shown that the personality of an invader can have significant impacts on the invasion dynamics for that species. Therefore, this study examined the impact of personality on both competitive success and predation susceptibility of the highly invasive round goby (Neogobius melanostomus

This thesis analyses the relation between working hours and four different economic outcomes, productivity, employment, wellbeing, and fertility. The first part of the analysis focusses on regressions of five different measures of weekly average working hours on the economic outcomes, while the second part deals with extensions that makes groups based on average income and mean working hours. Whil

Vad är innovation inom en organisation, och varför kämpar så många företag med att förnya sig? Syftet med denna uppsats var att undersöka på vilka sätt etablerade företag lyckas bibehålla sin innovation och entreprenörsanda, genom att se till två huvudaspekter vilka berör ett företags kultur och struktur. Målet var också att bidra till ämnet entreprenörskap, och undersökningsfrågan besvarades genoWhat is organizational innovation, and why do so many companies struggle with their revitalization? The purpose of this thesis was to examine in which ways established companies are able to sustain their innovativeness and entrepreneurial spirit, by looking at the main aspects of the company’s culture and structure. The aim was also to contribute to the field of entrepreneurship and the question w

Given the HIV/AIDS peak in the 1980s, Uganda has been hailed as a success story after having dramatically decreased the infection rate in the 2000s. However, the country’s HIV/AIDS rate has started to increase again in recent years. At the same time, homosexual males represent a key population whose needs must be taken into account if the pandemic is to be eradicated. Therefore, the thesis focuses

In light of high turnovers and low retention a growing interest in finding solutions to retain Millennials is occurring. The mismatch between Millennials’ value systems and the organisational values systems are high and one of the reasons for Millennials to leave the organisation. Yet, fundamental questions about the relation between value systems of Generation Millennials entering the workforce a

This thesis is a comprehensive analysis of the different regulatory designs and arguments shaping French law in order to hold French businesses liable for their human rights abuses occurring in global supply chains. It focuses on the innovative law proposal on the duty of vigilance for parent and ordering companies currently debated within the French Parliament, and France’s potential to make huma

There exists a knowledge gap in the literature on how international actors address artificial intelligence (AI) in international sustainability governance. By addressing this gap and bringing a critical perspective, this paper aims to enrich discussions on AI within international relations. First, this paper shows that the development and deployment of AI-based technologies are mainly seen as an o

An important manifestation of severe COVID-19 is the ARDS-like lung injury that is associated with vascular endothelialitis, thrombosis, and angiogenesis. The intravascular innate immune system (IIIS), including the complement, contact, coagulation, and fibrinolysis systems, which is crucial for recognizing and eliminating microorganisms and debris in the body, is likely to be involved in the path

The Corona pandemic is changing the way we live and function as a society for at least the coming weeks or months. While it is a virus that does not take into account race, sex, class or age, it is also quite brutally revealing and reinforcing socio-economic inequalities which reflect the distribution of power in our societies. This, at the same time as it is showing us the strength of empathy, re