Search results

Recently, the single nucleotide polymorphism (SNP) identified as rs1260326, in the glucokinase regulatory protein (GCKR), was associated with hypertriglyceridemia in adults. Because accumulation of triglycerides in hepatocytes represents the hallmark of steatosis, we aimed to investigate whether this variant might be associated with fatty liver (hepatic fat content, HFF%). Moreover, because recent

There is a widespread belief that EU underperforms in the commercialization of publicly funded research and that the appropriate policy response is to transfer the ownership of intellectual property rights to Universities. This paper assesses the validity of these twin beliefs. In addressing the first, we limit ourselves to Sweden which still retains its "Teacher's Exemption" model. In spite of co

The plausibility of sympatric speciation has long been debated among evolutionary ecologists. The process necessarily involves two key elements: the stable coexistence of at least two ecologically distinct types and the emergence of reproductive isolation. Recent theoretical studies within the theoretical framework of adaptive dynamics have shown how both these processes can be driven by natural s

Resilience is often promoted as a boundary concept to integrate the social and natural dimensions of sustainability. However, it is a troubled dialogue from which social scientists may feel detached. To explain this, we first scrutinize the meanings, attributes, and uses of resilience in ecology and elsewhere to construct a typology of definitions. Second, we analyze core concepts and principles i

Workplace incivility has been shown to affect the individual and organization negatively. Studies have also indicated that workplace incivility is a relatively common phenomenon in Sweden. In connection with the pandemic, working life has become increasingly digital, which has normalized video meetings. Therefore, more knowledge is requested about workplace incivility in digital meetings. This pre

Introduction: Trauma stress and neuro-inflammation caused by surgery/anaesthesia releases cytokines. This study analysed impact of Auditory Evoked Potential Index (AAI) depth-of-anaesthesia titration on the early plasma IL-6 release after eye surgery under general anaesthesia. Method: This is a subgroup analysis of a prospective randomized study on the effect of auditory evoked potential guided an

The city of Helsingborg in Sweden has since 2010 been conducting a development work of its social housing programme. The city has built up a Housing First service, which today comprises 60 tenants, and has good results. Through two pilot projects, the city has also tried to develop the other parts of the social housing programme that previously was built on the staircase model. The ambition was to

Analyses of intraspecific genetic structure can promote the conservation of genetic diversity of rare or declining plant species by enabling identification of proper management units. Here we investigate the genetic structure of the annual hemiparasitic herb Rhinanthus angustifolius to evaluate the genetic distinctness of two currently described subspecies and three habitat-related groups of popul

Timber-concrete composite structures (TCCs) are widely gaining interest in Europe and America, because of its high strength and low energy-consumption structure. The key design point of timber-concrete composite structures are to ensure the reliability of the shear connectors. The objective of this paper was to predict structural response with finite element (FE) analysis and provide shear propert

Aims. The glycosphingolipid beta-galactosylceramide-3-O-sulfate (sulfatide) is present in the secretory granules of the insulin producing beta-cells and may act as a molecular chaperone of insulin. The final step in sulfatide synthesis is performed by cerebroside sulfotransferase (CST) (EC 2.8.2.11). The aim of this study was to investigate whether two single nucleotide polymorphisms (SNP), rs2267

Neutrophilic granulocytes contain the 55 kDa bactericidal/permeability-increasing protein (BPI). BPI binds to lipopolysaccharides (LPS), and exerts bacteriostatic and bactericidal effects against a wide variety of Gram-negative bacterial species. We have investigated the subcellular location of BPI in immature and mature neutrophils using cryotechnique for immunoelectron microscopy. BPI was found

Inflammation and ischemia have a synergistic damaging effect in the immature brain. The role of tumor necrosis factor (TNF) receptors 1 and 2 in lipopolysaccharide (LPS)-induced sensitization and tolerance to oxygen-glucose deprivation (OGD) was evaluated in neonatal murine hippocampal organotypic slices. Hippocampal slices from balb/c, C57BL/6 TNFR1(-/-), TNFR2(-/-), and wild-type (WT) mice obtai

Background: Use of bio-based diesel is increasing in Europe. It is currently produced from oilseed crops, but can also be generated from lignocellulosic biomass such as straw. However, removing straw affects soil organic carbon (SOC), with potential consequences for the climate impact of the biofuel. This study assessed the climate impacts and energy balance of biodiesel production from straw usin

Looking at two historical romances by women writers, Kathleen Graves’ Exile: A Tale of Old Tasmania (1945) and Isabel Dick’s Wild Orchard (1946), this article seeks to examine narratives of an early nineteenth-century Van Diemen’s Land that are apparently at odds with the 1940s Tasmania it was to become. Drawing on Giorgio Agamben’s “state of exception” as the theoretical underpinnings for this es

Aim: To investigate the prevalence of general and back pain in children with cerebral palsy and the relationships between scoliosis and back pain. Methods: Cross-sectional register study based on data from the Swedish Cerebral Palsy Follow-Up Programme. Descriptive analyses and logistic regression to regress age, sex, gross motor function, windswept, hip extension and source of report on the prese

J-wave pattern has been recognized as an arrhythmic risk marker, particularly in myocardial infarction patients. Mechanisms underlying J-wave development in ischemia remain unknown. In myocardial infarction model, we evaluated activation time delay as a prerequisite of J-wave appearance and predictor of ventricular fibrillation. Body surface ECGs and myocardial unipolar electrograms were recorded

Objective To compare several methods of missing data imputation for function (Health Assessment Questionnaire) and for disease activity (Disease Activity Score-28 and Clinical Disease Activity Index) in rheumatoid arthritis (RA) patients. Methods One thousand RA patients from observational cohort studies with complete data for function and disease activity at baseline, 6, 12 and 24 months were sel