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In vitro reassembled aggregates of cartilage proteoglycan (aggrecan) were studied by glycerol spraying/rotary shadowing electron microscopy and compared to the corresponding native (i.e. never dissociated) structures. In both cases a tightly packed central filament structure was observed consisting of the hyaluronate binding region (HABR) of the proteoglycan, link protein (LP) and hyaluronate (HA)
A new approach to the design of time windows is presented for detection of transient-evoked otoacoustic emissions (TEOAE). The windows are designed with reference to a minimum mean square error criterion involving the correlation properties of the ensemble of responses. Latency information is introduced in the detection process by windowing at different scales that result from wavelet decompositio
Popular Abstract in Swedish Tekniken för vitreoretinal kirurgi har utvecklats betydligt de senaste åren, både vad gäller metodik och instrumentering. Allt fler sjukdomstillstånd i näthinnan kan nu behandlas. För att utveckla dessa metoder vidare, och även öka kunskapen bakom verkningsmekanismen för deras effektivitet, är standardiserade djurmodeller där både funktion och histologi kan utvärderas aThe field of vitreoretinal surgery has expanded greatly over the last decades. A continuous refinement of surgical methods and instruments has increased the number of treatable retinal disorders. Vitrectomy, retinectomy and laser treatment are all part of the modern surgical arsenal. In order to further develop and refine these methods, and also to improve the knowledge of the mechanisms behind th
Abstract. My main claim is that explanations are fundamentally about relations between concepts and not, for example, essentially requiring laws, causes, or particular initial conditions. Nor is their linguistic form essential. I begin by showing that this approach solves some well-known old problems and then proceeds to argue my case using heuristic analogies with mathematical proofs. I find that
Out-of-plane nuclear motion stimulated in the core-excited state and symmetry breaking due to this nuclear motion have been investigated for B Is excitation in the BF3 molecule by a combination of three different experimental methods: angle-resolved ion-yield spectroscopy, vibrationally resolved resonant Auger electron spectroscopy and quadruple-ion coincidence momentum-imaging technique. (C) 2002
The subject of this thesis is the pushforward map on compactly supported distributions induced by a smooth mapping. Being the adjoint of the natural pullback operation on the class of smooth functions, the pushforward map is always well-defined, and as such it must be regarded as one of the fundamental operations of distribution theory. This thesis has two main aims: The first of these is to give
The genomes that organisms transmit between generations contain information about different kinds of functions. The genome with the "best" mix and number of genes for these functions is the one that natural selection favours. Here I introduce a new way to model simple organisms with genes for external and internal functions, and use it to study the evolution of genome size. The external functions
This paper presents an analysis of phase noise in multiphase LC oscillators, and measurement results for several CMOS quadrature-voltage-controlled-oscillators (QVCOs) working in the 2-GHz frequency range. The phase noise data for a so-called BS-QVCO (-140 dBc/Hz or less at 3 MHz frequency offset from the carrier, for a power consumption of 20.8 mW and a figure-of-merit of 184 dBc/Hz) show that ph
Popular Abstract in Swedish Utformningen av fattigvården och de arbetskrav man ställer på mottagarna har alltid varit kontroversiella frågor i socialpolitiken, såväl under fattig- och arbetshusens tidsålder under 1800-talet, som i nuvarande diskussioner om socialbidrag och aktivering av bidragstagarna. Den första delen av avhandlingen diskuterar begreppen fattigdom, marginalisering och social utesManagement of poor relief and work demands have been controversial questions in social policy during the workhouse era of the nineteenth century as well as in current discussions on social assistance and activation of recipients. The first part contains a discussion on the concepts of poverty, marginalisation, and social exclusion, and continues with an overview of activation policies for recipien
Eleven healthy women with regular menstrual cycles were examined with a combination of two-dimensional real-time ultrasound and color and spectral Doppler techniques on the 7th day after follicular rupture, and on the 1st, 2nd, 3rd and 4th days of menstrual bleeding. Both uterine arteries, arteries in the stroma and hila of both ovaries, in the wall of the largest follicle of the non-dominant ovar
Falling birth rates within the European Union have given rise to a number of studies, trying to analyse and interpret why women (and men) choose not to have (many) children. One attempt in this direction is made by an ongoing EU-project, involving eight countries, including Sweden. Qualitative interviews focusing on couples' decisions to have- or not have - children have been carried out in each c
The evolution of dispersal was investigated in an adaptive individual-based metapopulation model, which allowed for demographic and environmental stochasticity. The individual dispersal behaviour was determined by a one-locus genotype subjected to simple inheritance and mutation. Dispersal behaviour could therefore evolve through the genotype–phenotype mapping and the selection regimes stemming fr
Dextran-conjugated EGF (EGF-dextran) has a potential use for targeted radionuclide therapy of tumors that overexpress the epidermal growth factor receptor (EGFR). There are plans to treat both bladder carcinomas and malignant gliomas with local injections of radiolabeled EGF-dextran since these tumors often express high levels of EGFR. In this report we show that EGF and EGF-dextran differentially
Popular Abstract in Swedish Sjukgymnaster har behandlat patienter i samband med kirurgisk behandling sedan början på 1900-talet och den dominerande uppgiften har varit att förebygga lungkomplikationer och blodproppar samt att bedöma behovet av vidare rehabilitering efter utskrivning. Den medicinska utvecklingen går emellertid snabbt framåt och sjukgymnasten har en utmanande uppgift i att utveckla The overall aim of this work was to study the influence of surgery on energy expenditure (EE) during working capacity measurements and during walking. In the first study the aim was to investigate whether two different devices were sensitive enough to reveal differences in energy expenditure during treadmill walking, and if the measurements were reproducible. It was shown that an airflow of 42.5
Purpose. In previous studies of subretinal transplantation in rabbits, the host photoreceptor layer seemed to prevent the bridging of neuronal fibers between the graft and the host retina. The current study was undertaken to determine whether the same phenomenon occurs in transplants to the subretinal space of the vascularized retina of rats. Bridging of fibers was examined in transplants to anima
As the ‘third wave’ progressed it has been argued that democratisation should be analysed in terms of partial regimes rather than with multidimensional concepts of democracy. This article analyses the democratic qualities of one such partial regime, albeit arguably the core dimension of representative democracy: multiparty elections. The analysis focuses on the three basic democratic values of ele
