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Aims/hypothesis We sought to establish the molecular and pathological changes predisposing diabetic and non-diabetic patients to the development of carpal tunnel syndrome (CTS). Methods The posterior interosseous nerve (PIN) was biopsied in 25 diabetic and 19 non-diabetic patients undergoing carpal tunnel decompression for CTS. Detailed morphometric and immunohistological analyses were performed i
Background:Three prospective studies have evaluated the association between dietary acrylamide intake and endometrial cancer (EC) risk with inconsistent results. The objective of this study was to evaluate the association between acrylamide intake and EC risk: for overall EC, for type-I EC, and in never smokers and never users of oral contraceptives (OCs). Smoking is a source of acrylamide, and OC
In this study, we investigate for the first time the efficiency of an environmentally sustainable extraction technique (pressurized liquid extraction, PIE) in conjunction with a fast separation technique (ultra-high performance liquid chromatography, UHPLC) coupled to a selective mass spectrometry (MS) detector (quadrupole time-of-flight, qTOF) to extract, separate and quantify fifteen intact-gluc
To describe, at patient-level detail, the determining events and factors involved in the development of a country's HIV-1 epidemic.
In recent years much interest has been shown in the process of thermohaline mixing in red giants. In low- and intermediate-mass stars this mechanism first activates at the position of the bump in the luminosity function, and has been identified as a likely candidate for driving the slow mixing inferred to occur in these stars. One particularly important consequence of this process, which is driven
Cloud microphysics is substantially affected by aerosol loading and the resulting changes in the reflective properties of the clouds can significantly affect the global radiation budget. A study of how marine low-level clouds over Barents Sea and the northern parts of the Norwegian Sea are affected by air mass origin has been performed by combining ground-based aerosol measurements with satellite
Low-energy-electron emission from resonant Auger final states via intermolecular Coulombic decay (RA-ICD) has previously been described as a promising scenario for controlling radiation damage for medical purposes, but it has so far only been observed in prototypical atomic and molecular van der Waals dimers and clusters. Here, we report the experimental observation of RA-ICD in an aqueous solutio
Scholarship in the last decades has increasingly paid attention to the rhetoric of race and peoplehood in early Christian literature. It has been shown how the construction of Christian identity took place through ethnic reasoning, with writers using metaphors of parenthood, kinship, homeland and descent to express what it meant to be a Christian. These studies have typically focused on pre-Consta
Background Suicide is more common among males and in older age, but the understanding of sex-specific and age-specific risk indicators is limited. Objective To describe the sex-specific and age-specific prevalence of 25 suicide risk indicators in the year preceding suicide and estimate their associations with suicide. Methods Register-based population-nested case-control study in Sweden, 2009–2021
Objectives: To analyze device designs, similarities and overlaps of custom-made fenestrated arch endografts intended for mid/distal arch thoracic endovascular aortic repair. Materials and Methods: A multicenter cross-sectional study analyzing custom-made anonymized graft plans was performed. Graft plans were included from a cohort of mid/distal aortic arch repairs using custom-made fenestrated aor
The ubiquitous skin colonist Staphylococcus epidermidis elicits a CD8+ T cell response pre-emptively, in the absence of an infection1. However, the scope and purpose of this anticommensal immune programme are not well defined, limiting our ability to harness it therapeutically. Here, we show that this colonist also induces a potent, durable and specific antibody response that is conserved in human
Gallstone disease is common in the Western world, and approximately 15,000 cholecystectomies and 9000 endoscopic retrograde cholangiopancreatographies (ERCPs) are performed each year in Sweden. While being safe, the high frequency of these procedures has a significant cumulative impact on health in the community, exceeding those of many complex procedures for malignant conditions. Compliance with
Purpose: The Paleolithic Diet Fraction (PDF) estimates the proportion of absolute dietary intake derived from food groups included in the Paleolithic diet. In the Malmö Diet and Cancer Study (MDCS), higher PDF and lower systemic low-grade chronic inflammation (SLGCI) have been associated with lower cardiometabolic morbidity and mortality. We examined associations between PDF and SLGCI in the MDCS.
BACKGROUND AND OBJECTIVES: Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by 3 core symptom complexes: parkinsonism, cerebellar syndrome, and dysautonomia. Recent Movement Disorder Society (MDS) criteria allow for the clinical diagnosis of MSA based solely on motor symptoms, without requiring dysautonomia. This study aimed to evaluate the frequency and disease trajecto
Explicit finite element schemes are extensively used in industrial applications characterised by elevated strain rates and complex contact interactions. A central challenge in such simulations is the achievement of mesh-independent results while accurately capturing damage localisation and evolution. Gradient-enhanced damage models provide a robust regularisation framework. However, using a microm
Background: The dairy industry has gradually adopted cutting-edge technology in the past few years. This review explores the evolution and interventions of Artificial Intelligence (AI), Machine Learning (ML), and Industry 4.0 in the dairy industry through a systematic literature review and bibliometric analysis. Methods: The Web of Science, Scopus, etc. databases were used for bibliometric analysi
BACKGROUND: Patients receiving intraoperative ventilation during general anesthesia often have low end-tidal CO2 (etCO2). We examined the association of intraoperative etCO2 levels with the occurrence of postoperative pulmonary complications (PPCs) in a conveniently-sized international, prospective study named 'Local ASsessment of Ventilatory management during General Anesthesia for Surgery' (LAS
The impact of variations in the three-dimensional structure of the genome has been recognized, but solid cancer tissue studies are limited. Here, we performed integrated deep Hi-C sequencing with matched whole-genome sequencing, whole-genome bisulfite sequencing, 5-hydroxymethylcytosine (5hmC) sequencing and RNA sequencing across a cohort of 80 biopsy samples from patients with metastatic castrati
In this article, we use a crowd theoretical perspective to look at student crowds and how they have been managed through various subdivisions of student housing. How has the student cohort been territorialised and divided into entities according to differences in group sizes, gender, family constellations, etc., and how has housing played a role in these social differentiations? Using the history
