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Popular Abstract in Swedish Denna avhandling är resultatet av ett doktorandprojekt vid Kvartärgeologiska avdelningen, Lunds Universitet. Syftet med undersökningen var att rekonstruera vegetations-, klimat- och havsnivåförändringar på Skagi-halvön, norra Island, under sen-Weichsel och tidig-Holocen. Nordatlantområdet genomgick en serie dramatiska klimatväxlingar i samband med övergången från den sSediment sequences from five lakes on the Skagi peninsula, northern Iceland, were subjected to mineral magnetic analysis, carbon analysis, pollen analysis, plant macrofossil analysis, diatom analysis, radiocarbon dating and tephra analysis in order to make detailed reconstructions of vegetation, climate and sea level during the Late Weichselian and Early Holocene. The main purpose was to investiga

OBJECTIVE: To identify perinatal factors associated with cerebral palsy (CP). METHODS: This was a case-control study based on the Swedish Medical Birth Registry and the Swedish Hospital Discharge Registry, including 2,303 infants born in Sweden 1984-1998 with a diagnosis of CP and 1.6 million infants without this diagnosis. Odds ratios (ORs) with 95% confidence intervals (Cis) were calculated. RES

BACKGROUND AND PURPOSE: To determine how a recently proposed clinical stroke subclassification corresponds to specific findings on computed tomography (CT) and magnetic resonance imaging (MRI) of the brain. METHODS: Two hundred twenty-eight patients with first-ever stroke were divided into four clinical subgroups: (1) total anterior circulation syndrome: both cortical and subcortical symptoms from

Popular Abstract in Swedish Variabilitet i ett läkemedels farmakokinetiska (hur ett läkemedel omsätts i kroppen) och farmakodynamiska (vilken effekt ett läkemedel har) egenskaper kan resultera i att olika individer som erhållit samma dos av ett läkemedel får olika effekter av läkemedel. Biverkningar eller utebliven effekt kan innebära allvarliga konsekvenser för den enskilda individen. VariabiliteVariability in pharmacokinetic and pharmacodynamic parameters between individuals can be due to intrinsic and extrinsic factors. In this thesis three different areas regarding sources of variability have been investigated. 1. Formulation properties as an extrinsic source of variability. Lipophilic substances often have poor oral bioavailability and high inter- and intraindividual variability. High

Essentially pure orthorhombic M1 and pseudo-hexagonal M2 phases were prepared using the precursor method. Consistent with literature the M1 phase was shown to be effective for propane ammoxidation to acrylonitrile while the M2 phase was essentially inert for propane activation. Both phases convert propene efficiently to acrylonitrile. Both phases show a significant selectivity dependence on the am

Moraxella catarrhalis is an airway pathogen whose role in infection has been increasingly recognized in recent years. Most authorities in this field now agree that M. catarrhalis causes significant morbidity and is not just a harmless commensal. The universal prevalence of BRO ?-lactamases in this pathogen is a serious concern. In addition, M. catarrhalis may be further propelled into a more promi

This thesis seeks to reveal the relationship of language and content in a Moroccan short story. These relationships are defined as such by pointing out single linguistic elements in the story’s language which reproduce a certain component of the story’s content. The main question hereby asks for the effect of the author’s language on the message itself – for, as the carrier of information, languag

The exemptions for certain activities in the public interest of art.132(1) of the VAT Directive are confined to those supplies of goods and services carried out by bodies governed by public law. Article 133 of the Directive enables the Member States to grant to bodies other than those governed by public law, in accordance with certain conditions, the exemption of those transactions related to hosp

Popular summary The fate of non-steroidal anti-inflammatory drugs The knowledge about distribution of drugs between sewage sludge, water phases and water living organisms is vital for predictions of the fate and transport routes of toxic substances to the environment. And the distribution of drugs in the environment can be used as a base for risk assessments and it also can be used to define desir

With the eruption of the sovereign debt crisis, a huge threat and disaster had been brought to the European Union, the member states and the entire euro zone. The ongoing financial crisis has made it very difficult or even impossible for some member states within the euro zone to re-finance the government debt without the third party’s assistance. Greece being one of those states is experiencing t

Creativity has been of research interest for centuries and its relationship with other constructs has been established; however, these links mostly study creativity with a single other construct. The purpose of this study was to investigate the relationship between psychological safety, tolerance of ambiguity, playfulness and creativity; they have been individually linked together but no complex m

Neuron glial 2 (NG2) cells become strongly activated in injured brain areas. The activation is characterized by increased proliferation as well as increased expression and shedding of the proteoglycan NG2 expressed on their cell surface. It is currently not known how these cells respond to low-grade neuroinflammation provoked by systemic inflammation. To investigate this, we analyzed NG2 cell prol

ABSTRACT: BACKGROUND: The two-step dilute acid hydrolysis (DAH) of softwood is costly in energy demands and capital costs. However, it has the advantage that hydrolysis and subsequent removal of hemicellulose-derived sugars can be carried out under conditions of low severity, resulting in a reduction in the level of sugar degradation products during the more severe subsequent steps of cellulose hy

In the present work we determine the adsorption site of two polyatomic molecules, methoxy and ethoxy, on Cu(100). This is accomplished by comparing experimental intramolecular vibrational modes to the corresponding modes calculated by first principle methods. We explore the three different high symmetry adsorption sites on top, bridge and hollow using several different metal clusters to represent

Purpose: Off-target binding in the skull and meninges is observed in some subjects undergoing tau positron emission tomography (PET) and could potentially differ between men and women. In this study we elucidate sex differences in tau off-target binding using three different tau PET tracers. Methods: 541 cognitively unimpaired amyloid-β negative participants underwent tau PET using [18F]flortaucip

The sustainable management of the ocean as a global food source has been prominent in recent debates due to the disproportionate rate of human consumption, depletion of fish stocks and shortcomings in conservation efforts. Criticisms from various sectors on the effectiveness of Regional Fisheries Management Organizations (RFMO) in relation to their mandates have prompted performance reviews (PRs)

Background: Gun violence is a global health problem. Population-based research on firearm-related injuries has been relatively limited considering the burden of disease. The aim of this study was to analyze nationwide epidemiological trends of firearm injuries. Methods: This is a retrospective nationwide epidemiological study including all patients with firearm injuries from the Swedish Trauma Reg