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When it comes to random walk on the integers Z, the arguably first step of generalization beyond simple random walk is the class of one-sidedly continuous random walk, where the stepsize in only one direction is bounded by 1. Moreover, the time until state 0 is hit by left-continuous random walk on Z has a direct connection to the total progeny in branching processes. In this article, the probabil
Global climate change is one of the greatest environmental threats facing humanity and it is affecting every country on every continent. Recent evidence confirms a close liaison between climate change induced hazards and the built environment, as the built environment demonstrates a high fragility and vulnerability to hazardous situations. The impact of climate change is particularly pertinent to
Alzheimer’s disease, the most common form of dementia, is characterized by progressive cognitive decline and the accumulation of amyloid-beta (Aβ) and tau neurofibrillary tangle (NFT) pathology. The medial temporal lobe (MTL) is one of the earliest sites of NFT pathology, crucial for memory functioning, and is made up of cytoarchitectonic and functionally different subregions. These subregions are
BACKGROUND: Malignancies of the liver and bile ducts are associated with high recurrence rates after surgery and poor prognosis when disseminated. Medical treatment has been improved in recent years, with chemotherapy, targeted therapy and checkpoint inhibitors offering opportunities to influence the course of the diseases. Many patients do not benefit from treatment, however, and predictive and p
Current trends aim at improving the surface integrity of aerospace Ni-based superalloys by reducing the temperature rise in the cutting zone in order to minimize tool wear, as well as reducing the thermally induced tensile residual stresses on the machined surface. The manufacturing industry is also driven by developing high performance sustainable machining processes. Cryogenic machining (CM) usi
SI Engine knock is caused by autoignition in the unburnt part of the mixture (end-gas) ahead of the propagating flame. Autoignition of the end-gas occurs when the temperature and pressure exceeds a critical limit when comparatively slow reactions - releasing moderate amounts of heat - transform into ignition and rapid heat release. In this paper the difference in the heat released in the end-gas
CERTEC intends to develop an autonomous grasping function, but first user requirements have to be studied. Therefore, user trials have been carried out on the RAID workstation (Robot to Assist the Integration of the Disabled) at the Rehabcentrum Lund-Orup in Höör, Sweden. This paper will describe the control methods used in these trials as well as the results of the trials.
PURPOSE: In the context of oncologic therapy for children, radiation therapy is frequently indicated. This study identified the frequency of and reasons for the development of high-grade acute toxicity and possible sequelae.MATERIALS AND METHODS: Irradiated children have been prospectively documented since 2001 in the Registry for the Evaluation of Side Effects After Radiation in Childhood and Ado
This article proposes a critical legal analysis of the jurisprudence of the Inter-American Court of Human Rights regarding indigenous peoples’ rights to lands, participation, and consultation. It focuses on the role that cultural diversity as a legal standard has played in the recognition of the indigenous peoples’ right to consultation and participation in all matters that directly affect them, a
Fetal guinea-pig epiphyseal chondrocytes were isolated enzymatically, aggregated, and the aggregates maintained in organ culture. As revealed by light and electron microscopy, the cultures produced a typical cartilaginous matrix, but no calcification occurred. Exposure of aggregating cells, or preformed aggregates, to colchicine or vinblastihe at 10-5 M concentration led to disappearance of the mi
