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How do science teachers perceive student engagement and its importance for teaching and what strategies do they use to create it? When 21 experienced science teachers in 4 focus groups discussed these questions, they brought up behavioural aspects, but also less visible emotional and cognitive aspects, as well as reciprocal aspects of teacher and student engagement. One teacher described engagemen
Both the European Convention for the Protection of Human Rights and Fundamental Freedoms (ECHR) and the Charter of Fundamental Rights of the European Union (CFR) include the right to a fair trial by an independent and impartial tribunal established by law. The exact meaning of the phrase ‘an independent and impartial tribunal established by law’ has developed in case law. In this article, I analys
The article sheds light on the significant fundraising and relief activities for Ireland during the Great Famine (1845–50) initiated in 1847 by the Italian philosopher and cleric Antonio Rosmini and his network in Savoy-Piedmont, Lombardy-Venetia and England. By analysing Rosmini's philosophical and political writings, the article demonstrates that Rosmini considered aid in times of crisis as an a
This article analyses the participation of individuals, networks and international organizations in transnational fundraising aimed at providing humanitarian relief aid. Focusing on fundraising campaigns organized in the Italian states in favour of Ireland in 1847, when the Great Famine scourged its population the most, the article highlights the agency of the fundraisers in setting in motion an e
The Old Romance continuations of Latin sic, such as Old French si and Old Italian sì, involve four different functions, all of which are referred to here as sic. The first one, which is closest to the original Latin usage, is that of a lexical adverbial, while the other three are functional elements introducing main clauses: the second sic follows elements preposed to the verb, the third one intro
Standing at a crossroads, where ongoing 'slowbalisation' coincides with new forces such as the outbreak of the Covid-19 pandemic, heightened geopolitical tensions, the emergence of disruptive technologies and the increasing urgency of addressing environmental challenges, many important questions remain unsolved regarding the nature and impact of the current economic globalisation. This special iss
This article combines the methodological approaches and insights of two scholars working in distinct regions of the early modern world, namely West Africa and Central Asia, to consider border-making outside of Europe before the nation state. Using borders to understand historical developments is not unprecedented and decades of borderland studies have shown how borders result from, and are affecte
Woolly mammoths had a set of adaptations that enabled them to thrive in the Arctic environment. Many mammoth-specific single nucleotide polymorphisms (SNPs) responsible for unique mammoth traits have been previously identified from ancient genomes. However, a multitude of other genetic variants likely contributed to woolly mammoth evolution. In this study, we sequenced two woolly mammoth genomes a
Following years of increasing bureaucracy and micro-management, there is a need for more trust in the judgement of street-level professionals and citizens in the public administration. After an intense debate in Sweden for several years, the Swedish Government launched a trust reform in 2016. This was organized around a government commission, called the Trust Commission. At the centre of its work
After a 7-year slowdown in economic growth in the previous decade, LAC opened this decade with the adverse effects of Covid. The economic slowdown and the health crisis jeopardized the SDGs’ implementation in the region. In this chapter, the authors revisit the old question of whether the previous decade of LAC is another lost decade, mainly adding the environmental dimension to the economic and s
Aquaporin-9 (AQP9) is a facilitator of glycerol and other small neutral solute transmembrane diffusion. Identification of specific inhibitors for aquaporin family proteins has been difficult, due to high sequence similarity between the 13 human isoforms, and due to the limited channel surface areas that permit inhibitor binding. The few AQP9 inhibitor molecules described to date were not suitable
Seventy-four addictive alcoholic subjects were investigated shortly after a period of excessive drinking and were compared with 18 alcoholic subjects who had not been drinking for at least six months. No difference was observed in total white cell count or number of circulating granulocytes. Lymphocyte count was significantly lower in alcoholics whose last alcoholic bout had been three months or m
Neurodegenerative disorders (NDDs) such as Huntington's disease (HD) and the spectrum of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are characterized by progressive loss of selectively vulnerable populations of neurons. Although often associated with motor impairments, these NDDs share several commonalities in early symptoms and signs that extend beyond motor dysfunction
The engram encoding the interval between the conditional stimulus (CS) and the unconditional stimulus (US) in eyeblink conditioning resides within a small population of cerebellar Purkinje cells. CSs activate this engram to produce a pause in the spontaneous firing rate of the cell, which times the CS-conditional blink. We developed a Bayesian algorithm that finds pause onsets and offsets in the r
