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Introduction: Calcium is an important ubiquitous second messenger regarding the maintenance of cellular homeostasis, and is therefore tightly regulated. Calcium induces cell death when internalised into cancer cells after permeabilization of the cell membrane by electroporation. It is established that radiation causes damage to the lipids and proteins of the cell membrane; and ionizing radiation a
The Women, Peace and Security agenda (WPS) argues for women’s rights and recognition of women’s situations in all stages of a conflict. Previous research has shown how refugee women seem to be overlooked in international legislation. Existing research considering the WPS agenda has mainly focused on issues of implementation and discourses. This study aims to explore how conceptualizations of secur
Effective and fair taxation is imperative for development and thus sustainable peace in post-conflict countries; yet there is a glaring paucity of generalizable research on the subject. Drawing on theories from Political Economy and Comparative Politics this thesis investigates how political veto powers affect these states’ ability to mobilize domestic resources. An integrated model of delayed pol
This thesis assesses aspects of the wetland development, permafrost dynamics and associated changes in carbon and nutrient cycling of the Stordalen Mire in northern Sweden. Various ecological and biogeochemical analyses of one peat and two lake sediment sequences were conducted, including analyses of organic matter and carbonate content, mosses, diatoms, testate amoebae, pigments, carbon and nitro
It is important to understand the role that different predators can have to be able to predict how changes in the predator assemblage may affect the prey community and ecosystem attributes. We tested the effects of different stream predators on macroinvertebrates and ecosystem attributes, in terms of benthic algal biomass and accumulation of detritus, in artificial stream channels. Predator richne
The age specific patterns of reproduction and mortality dictated by the life history of an organism apply to potential invaders as well as resident species of an area, but whether certain life history traits are more invasive than others is an unresolved issue. We analyze a two-population system of an invading and a resident species and test the effects of age on the probability to invade when the
The solids-flux theory has been used for half a century as a tool for estimating concentration and fluxes in the design and operation of secondary settling tanks during stationary conditions. The flux theory means that the conservation of mass is used in one dimension together with the batch-settling flux function according to the Kynch assumption. The flux theory results correspond to stationary
Background: Fragility fractures are a major health problem world wide and the numbers are growing due to ageing populations. Early identification of individuals at risk for osteoporosis and fracture, enabling preventive measures and treatment is essential. Bone strength is partly dependent on lifestyle but genetic factors account for approximately 70-80%. Parathyroid hormone (PTH) is the key regul
Popular Abstract in Swedish Grundvatten, det vatten som förekommer i hålrum i underjorden, är en av våra allra viktigaste naturresurser. Grundvattnet utgör den absolut största andelen för oss tillgängligt färskvatten och används för att producera mat och som processvatten inom olika industrier. Ungefär hälften av jordens dricksvattenförsörjning baseras på grundvattenuttag och ekosystem världen övePesticides are known to occur in groundwater worldwide. However, long-term pollution concerns and cause-effect relationships for specific regions remain limited. This thesis explores the occurrence of pesticides in south-Swedish groundwater, with the aims of providing a better knowledge basis for assessment and management of present-day and future pollution risks. The investigations are restricted
Popular Abstract in Swedish Tumörer i ben och mjukdelar är vanliga men utgör endast 1 % av alla maligna neoplasier. De elakartade tumörerna är ofta utmanande att diagnostisera pga deras relativt likartade morfologi samt att de är ovanliga. Således är all tilläggsinformation värdefull och genetiska analysmetoder kan bidra med information som är användbar och i vissa fall tom avgörande för diagnostiTumors of bone and soft tissue are common but only constitute 1 % of all malignant tumors. The malignant tumors are often difficult to diagnose due to their rarity and morphological resemblance between subtypes. This makes the diagnostic process challenging. Thus, there is a need for ancillary techniques, such as genetic analyses, not only for diagnostic purposes, but also for obtaining informatio
Ship-generated waves were investigated in the Gota alv river, which is a major waterway on the Swedish west coast between the sea and Lake Vanern. Ships with a typical size of 85x15x5 m (lengthxwidthxdraft) travel at speeds between 5 and 10 knots, generating waves that cause sediment transport and erosion along the river bed and banks. Field measurements of the wave properties and turbidity were c
The effect of modulating the structure of thin pentacene (C22H14) films by a nanopatterned inert substrate, known as hexagonal boron nitride nanomesh, is reported. Films of different thickness are grown and characterized by x-ray absorption, core-level photoemission, low-energy electron microscopy, microbeam low-energy electron diffraction, and scanning tunneling microscopy. Initially the pentacen
Researchers often statistically control for means when examining individual or age-associated differences in variances, assuming that the relation between the 2 is linear and invariant within and across individuals and age groups. We tested this assumption in the domain of working memory by applying variance-heterogeneity multilevel models to reaction times in the n-back task. Data are from the CO
The polarizability and other properties have been studied for F(-), Cl(-), Br(-), and HCOO(-) in water using a combined quantum chemical statistical mechanics simulation model that explicitly takes into account the Pauli repulsion as well as the electrostatic coupling between the QM system and the classical surroundings. It is shown that the surrounding molecules significantly reduce both the pola
We prepared alpha- and beta surface phases of GaAs(0 0 1)-c(4 x 4) reconstruction by molecular beam epitaxy (MBE) using As-4 and As-2 molecular beams, respectively, and examined them by angle-resolved ultraviolet photoelectron spectroscopy (UPS) and X-ray photoelectron spectroscopy (XPS) with synchrotron radiation as an excitation source. The UPS valence band spectra and the XPS 3d core level data
Objective: To describe dietary protein intakes and their food sources among 27 redefined centres in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: Between 1995 and 2000, 36 034 persons, aged between 35 and 74 years, were administered a standardized 24-h dietary recall (24-HDR) using a computerized interview software programme (EPIC-S
Popular Abstract in Swedish Inledning I detta avhandlingsarbete studeras Mycoplasma pneumoniae (MP) och influensa virus ur olika perspektiv. Dessa två smittämnen orsakar båda årliga utbrott med luftvägsinfektioner som ibland blir omfattande epidemier. I båda fallen kan symptomen variera från lätta förkylningsbesvär till mycket svåra, ibland livshotande lunginflammationer. Infektion med MycoplasmaDiagnostic tests based on nucleic acid amplification have become available for Mycoplasma pneumoniae (MP) and influenza viruses. Here, an MP PCR test detected 100% of infections during the first three symptomatic weeks, whereas classical serology detected 21% week 1, 56% week 2, and 100% week 3. Positive PCR results were uncommon in healthy individuals. Levels of MP DNA were significantly higher i
Objective: The objective of this study was to assess the level of agreement between stroke subtype classifications made using the Trial of Org 10172 Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems. Methods: Study subjects included 13,596 adult men and women accrued from 20 US and European genetic research centers participating in the National Institute of Neurol
