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Organic acids, central to terrestrial carbon metabolism and atmospheric photochemistry, are ubiquitous in the troposphere in the gas, particle, and aqueous phases. As the dominant organic acids in the atmosphere, formic acid (FA, HCOOH) and acetic acid (AA, CH3COOH) control precipitation acidity in remote regions and may represent a critical link between the terrestrial carbon and water cycles by
Background: There is a paucity of instruments designed to evaluate the multiple dimensions of the workplace as an educational environment for undergraduate medical students. Aim: The aim was to develop and psychometrically evaluate an instrument to measure how undergraduate medical students perceive the clinical workplace environment, based on workplace learning theories and empirical findings. Me
Objective: Autism spectrum disorders are considered to be among the most heritable mental disorders, a notion based on surprisingly sparse data from small clinical studies. Population-based studies of the heritability of other neuro-psychiatric disorders and comorbidities among them have also been sparse. The authors sought to address both of these issues. Method: Parents of all Swedish 9- and 12-
This article seeks to outline a conceptual landscape that can assist us to better grasp how urban communities torn and traumatised by violent conflicts remain divided in peace and resistant to liberal peacebuilding efforts. It suggests that peacebuilding needs to be urbanised to better address and mitigate tensions and ethnocratic spatial practices in divided cities. The urban is suggested as a pr
Reproductive factors influence the risk of developing epithelial ovarian cancer (EOC), but little is known about their association with survival. We tested whether prediagnostic reproductive factors influenced EOC-specific survival among 1025 invasive EOC cases identified in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, which included 521 330 total participants (ap
It has been unclear whether ischemic stroke induces neurogenesis or neuronal DNA rearrangements in the human neocortex. Using immunohistochemistry; transcriptome, genome and ploidy analyses; and determination of nuclear bomb test-derived (14)C concentration in neuronal DNA, we found neither to be the case. A large proportion of cortical neurons displayed DNA fragmentation and DNA repair a short ti
Since the non-military dissolution of the political union with Norway in 1905, the myth of Sweden as a peace-power state, often with religious motivations, has been actual, and continuosly re-activated. In his ecumenical-political actions, Archbishop Nathan Söderblom was one of the most outstanding actors. Later, the political martyrdom of Count Folke Bernadotte, Dag Hammarskjöld, Raoul Wallenberg
In recent years questions concerning whether and how networks between small and medium-sized enterprises (SMEs) can serve as platforms for inter-organizational collective learning have attracted interest. In the present paper it is argued that two prerequisites for this are recognition of common needs and goals that contribute to the construction of a collective identity and the presence of promot
Background: Current information on the role of internists in the European countries is scarce. This report describes the results of a survey of the practice of internists in Europe. Methods: Two online questionnaire-based surveys were carried out by the European Board of Internal Medicine, one on the practice of internists and the other on postgraduate training in internal medicine. The national i
Inhibitors for galectin-1 and -3 were synthesized from thiodigalactoside and lactosamine by derivatization of the galactose C3. Introduction of 4-phenyl-1H-1,2,3-triazol-1-yl substituents at the thiodigalactoside C3 by CuAAC, targeting arginine-arene interactions, increased the affinity to 13 nM but yielded little selectivity. The builder 4-(4-phenoxypheny1)-1H-1,2,3-triazol-1-yl substituent, howe
During Botswana's four decades of high levels of growth the agricultural sector has lagged behind, with smallholder productivity being especially poor. This paper applies an equity perspective: its main claim is that one important explanation for the current lack of agricultural development is the unequal distribution of agricultural resources. It takes into account both the national institutional
Exome sequencing studies in complex diseases are challenged by the allelic heterogeneity, large number and modest effect sizes of associated variants on disease risk and the presence of large numbers of neutral variants, even in phenotypically relevant genes. Isolated populations with recent bottlenecks offer advantages for studying rare variants in complex diseases as they have deleterious varian
The developing high-resolution chronostratigraphy of the Cambrian provides an updated age model for various geologic and biotic events that occurred during this critical period of Earth history. Broad, time-specific patterns of lithofacies, such as organic-rich deposits, and biofacies appear to be consistent across all Cambrian paleocontinents. Records of important evolutionary events including fi
Structural features of neurons create challenges for effective production and distribution of essential metabolic energy. We investigated how metabolic energy is distributed between cellular compartments in photoreceptors. In avascular retinas, aerobic production of energy occurs only in mitochondria that are located centrally within the photoreceptor. Our findings indicate that metabolic energy f
The main aim of the study was to explore the extent to which familial hypercholesterolemia (FH) influences the life of the patients affected. The study employed a qualitative analysis of semi-structured interviews with 23 outpatients who were being treated following a diagnosis of heterozygous FH at a tertiary hospital in Göteborg, Sweden. Some interviewees reported concerns related to their medic
Ambiguous practices and identities of NGOs have become a source of increasing concern for all involved in development intervention. But apart from pointing at dishonest marketing and unfortunate unintended consequences of donors’ support, how can we understand these ambiguities? Based on an ethnographic study of local Bangladeshi NGOs, the article explores actions and behaviour of grassroots NGO s
The surface speciation of orthophosphate ions on goethite has been studied as a function of pH, time, total phosphate concentration, and ionic medium by means of diffuse reflectance FTIR spectroscopy. The samples were prepared in accordance with a distribution diagram of surface species as calculated from thermodynamic data. In agreement with the thermodynamic model three dominating surface comple
The changes in interface structure and chemical composition of a 99.995% pure nickel/yttria-stabilised zirconia (YSZ) interface were examined after heat treatment at 1000 °C in 97% H2/3% H2O with and without polarisation. Impedance spectroscopy was used for electrochemical characterisation. The results were compared to earlier investigations of a less pure nickel/YSZ interface. The pure interface
The anaphylatoxin C3a is a proinflammatory mediator generated during complement activation. The tight control of C3a receptor (C3aR) expression is crucial for the regulation of anaphylatoxin-mediated effects. Key factors regulating constitutive expression of the C3aR in the mast cell line HMC-1 and receptor induction by dibutyryl-cAMP in monomyeloblastic U937 cells were determined by functional ch
