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Infections due to the opportunistic fungus Candida have been on the rise in the last decades, especially in immunocompromised individuals and hospital settings. Unfortunately, the treatments available today are limited. Thrombin-derived C-terminal peptide (TCP-25) is an antimicrobial peptide (AMP) with antibacterial and immunomodulatory effects. In this work, we, for the first time, demonstrate th
Aims: The aim of this cross-sectional study was to examine the prevalence of the multidimensional phenomenon of fatigue in adults with congenital heart disease. Background: Adults with congenital heart disease are a growing population, and patient-reported outcomes can provide valuable information about the patient's experience of living with CHD. Fatigue is a multidimensional phenomenon that can
The persistence of patterns of decline or stagnation in developed countries has led to a renewed interest in the study of less developed regions. This renewed interest is informed by a variety of approaches, which range from studies on the unequal distribution of economic power and resources to analysis of regional endowments, such as human capital or quality of institutions. However, a persistent
Background: Parents face mental health challenges following their child's cancer diagnosis. However, it is unknown whether parental mental illness following a childhood cancer diagnosis influences the child's mortality.Patients and methods: Using several nationwide registers in Sweden, we identified children diagnosed with cancer between ages 0 to 14 from 2005 to 2016. Parental mental illness was
OBJECTIVE: Cone beam computed tomography (CBCT) can accurately assess erosive disease in the hands, wrists and feet in established rheumatoid arthritis (RA). The aim of this study was to compare CBCT with conventional radiography (CR) for the assessment of erosions in patients with early RA.METHODS: CBCT and CR of the hands, wrists and feet of 17 patients with treatment naive early RA were assesse
The purpose of this thesis is to discuss issues related to the ongoing reconciliation process between the Church of Sweden and the Sami people, with a comparative outlook towards Norway. The question I raise is under what conditions the Church is willing to seek reconciliation. Reports and other pertinent documents published by the Church have been analysed mainly through critical reading, seeking
BackgroundTranscatheter aortic valve implantation (TAVI) is a percutaneous catheter-based treatment of aortic stenosis as an alternative to open heart valve surgery. In cases of TAVI endocarditis, the treatment possibilities may be limited as surgical removal of the infected valve may be associated with a high risk in elderly, comorbid or frail patients. The propensity of bacteria to form a biofil
Previous research indicates that higher-order thinking skills (HOTS) have an important role in L2 learning. In an online learning context, e-assessment tasks are ideally designed to target these skills. A recently conducted study by Johansson (2020) indicates that HOTS e-assessment is relatively common in Swedish online English as a Foreign Language (EFL) courses. Generally, instructors’ perceptio
In this chapter, focus is on the period 1945-1960 and the discussion is divided into three thematic sections: First, macro-economic structures including growth trends and the composition of the economies. Second, colonial budgets including state finance, fiscal capacity, and economic policy. Third, changes in occupations, incomes, and living standards primarily for the African subjects. The text p
Introduction: Atrial septal defect is the third most common CHD. A hemodynamically significant atrial septal defect causes volume overload of the right side of the heart. Preterm children may suffer from both pulmonary and cardiac comorbidities, including altered myocardial function. The aim of this study was to compare the rate of adverse events following atrial septal defect closure in preterm-
This article aims to examine the nexus between social media, anti-corruption activism and democratisation in authoritarian regime contexts. It will investigate the complex ways in which civil society actors utilise art and humour on social media platforms to engage in covert anti-corruption activism. In doing so, we will show how, in authoritarian contexts, digital (social media) activists creativ
This paper explores the asymptotic distributions of low-dimensional patterns in linear regression with regularizers such as Lasso, Elastic Net, Generalized Lasso, and SLOPE, as the number of observations n grows and the penalty increases at rate n. While the asymptotic distribution of rescaled estimation errors is well-understood, convergence of patterns lacks proof in the literature, even for Las
Background:Aseptic loosening remains a main complication following total knee arthroplasty (TKA), requiring revision surgery. Radiostereometric analysis (RSA) can assess the risk of aseptic loosening. This study evaluated the migration and segmental motion of cemented and uncemented femoral and asymmetrical tibial Persona components (Zimmer Biomet) with model-based RSA.Methods:We conducted a rando
Accurately predicting the macroscopic behaviour of heterogeneous materials, particularly in thermo-electrically coupled systems, remains a challenging problem in materials science and engineering. Against this background, this study presents a comprehensive framework for the homogenisation of electrical conductors subject to strongly coupled thermo-electrical processes in (quasi-)stationary settin
This chapter reviews the growing body of epidemiological evidence linking long-term exposure to ambient air pollution with increased risk of dementia, including Alzheimer’s disease (AD) and vascular dementia (VaD). With air pollution now recognized as a potentially modifiable risk factor, the chapter explores mechanistic pathways, such as neuroinflammation and oxidative stress, through which pollu
