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Recognizing individual variability is essential for developing targeted, personalized medical interventions. Vocal fatigue is a prevalent symptom and complaint among occupational voice users, but its identification has yielded mixed results. Vocal fatigue is a complex issue with heterogeneous biophysiological responses to vocal demands among individuals. This research aims to classify individuals
Background: Older adults are underrepresented in suicide prevention research, even though suicide rates are higher in this age group (65+) than in any other age group in many countries worldwide. There are few clinical intervention studies that target this age group. A promising preventive intervention is the Attempted Suicide Short Intervention Program (ASSIP). Given differences in suicidal behav
Geomagnetic field models constrained by direct observations extend back some 400 years and the magnitude of decadal to centennial variations that they display is often assumed to be typical of the secular variation over longer timescales. Here we present archaeomagnetic directions from layered Neolithic hearths in Orkney, dating to around 3000 BCE, that challenge this assumption. Combining stratig
OBJECTIVES: This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To assess the benefits and harms of immunosuppressants with or without corticosteroids compared to corticosteroid monotherapy for the treatment of IgG4-related disease in people 18 years or older.
The microbiota colonizes each barrier site and broadly controls host physiology1. However, when uncontrolled, microbial colonists can also promote inflammation and induce systemic infection2. The unique strategies used at each barrier tissue to control the coexistence of the host with its microbiota remain largely elusive. Here we uncover that, in the skin, host-microbiota symbiosis depends on the
This chapter provides a brief overview of the aims of this book, how it is structured and the various chapters to be found therein. It summarises the main arguments made by the contributing experts, who come from both EU competition law as well fundamental rights backgrounds. It further provides an analysis of the new directions in digitalisation and their implications for future research.
Efficient and rapid host cell invasion is a prerequisite for an intracellular parasitic life style. Pathogens typically induce receptor-mediated endocytosis and hijack the force-transducing system of a host cell to gain access to a replication-competent niche. In striking contrast, apicomplexan parasites such as Plasmodium, the causative agent of malaria, and the human and animal pathogens Toxopla
Dopaminergic (DA) neurons exhibit significant diversity characterized by differences in morphology, anatomical location, axonal projection pattern, and selective vulnerability to disease. More recently, scRNAseq has been used to map DA neuron diversity at the level of gene expression. These studies have revealed a higher than expected molecular diversity in both mouse and human DA neurons. However
We use high-resolution (35pc) hydrodynamical simulations of galaxy formation to investigate the relation between gas accretion and star formation in galaxies hosted by dark matter haloes of mass at. At high-redshift, cold-Accreted gas is expected to be readily available for star formation, while gas accreted in a hot mode is expected to require a longer time to cool down before being able to form
Virtual Reality (VR) as a complementary tool for medical practitioners in the assessment and rehabilitation of people who have suffered a traumatic brain injury (TBI) is discussed. A pilot-study has been undertaken on a prototype VR assessment tool. The design involved nine occupational therapists with expertise in the care of traumatic brain injured patients and one (computer experienced) patient
We present a web-based method for mapping various relations between agents that have been involved in an emergency response operation. The method is based on combining a web-questionnaire with telephone interviews and it provides an efficient way of collecting large amount of information concerning the agents. By using the resulting network of agents it is possible to perform various network analy
Broadening conventional sociological concerns, this paper establishes a social psychological account of queer theory, and an associated understanding of subject formation, in order to examine the relationship between the continuously emerging self and the dressed body by taking its departure in the concept and phenomenon of cross-dressing. Focusing the interrelationship between bodily gestures and
The Bible appears regularly in Margaret Atwood’s novels, from The Edible Woman in 1969 to The Testaments in 2019. Atwood’s characters do not tend to be religious, but like most people in the Western world, they encounter the Bible in schools, at funerals, in headlines, advertisements, and occasionally from religious people themselves. Atwood’s Bible is a Christian Bible, the references running fro
