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Wear in forming tools and contact problems between sheet-metal and tool-material are common problems in manufacturing industries and sheet-metal-parts production. In this paper recent tool material experiences are presented. Quantitative determination of wear has been performed using micro hardness indentions made on the tool surface prior to pressings and thereafter measured. Wear tests are perfo
A historical analysis of Christian revivalist movements in England, Wales, Scotland and North America illustrating points of convergence and divergence with the Korean Christian revival of 1907.
Hipparcos observations of double stars, mainly A and F primaries, aremodelled in order to check the statistics of double-star solutions inthe Hipparcos Catalogue and to set quantitative limits on binarydistributions. The number of companions per primary is estimated to 0.25+/-0.05 for semi-major axes from 1 to 10 AU, and to 0.43 +/-0.20 for therange 10--100 AU. The total multiplicity found is betw
Seventeen globular clusters in the Large and Small Magellanic Clouds were observed in the mid-infrared wavelength region with the ISOCAM instrument on board the Infrared Space Observatory (ISO). Observations were made using the broadband filters LW1, LW2, and LW10, corresponding to the effective wavelengths of 4.5, 6.7, and 12 mum, respectively. We present the photometry of point sources in each c
Background: Standard anti-proliferative chemotherapy is relatively ineffective against slowly proliferating androgen-independent prostate cancer cells within metastatic sites. In contrast, the lipophilic cytotoxin thapsigargin, which causes apoptosis by disrupting intracellular free Ca2+ levels, is effective against both proliferative and quiescent (i.e., G(0)-arrested) cells. However, thapsigargi
Genotyping of hepatitis C virus (HCV) is important because of its clinical and epidemiological implications. We report here the distribution of HCV genotypes in various patient groups in Finland using a rapid and reliable HCV typing method based on restriction fragment length polymorphism (RFLP) of the amplified DNA from the 5' non-coding region of the genome. The reaction product from the primary
BACKGROUND: Cancer prevalence-the proportion of people in a population with a diagnosis of cancer-includes groups with widely differing cancer care needs. We estimated the proportions of the prevalent colon cancer cases requiring initial care, terminal care and follow-up. PATIENTS AND METHODS: Prevalence by year since diagnosis was estimated from incidence and vital status data on 243,471 colon ca
Previously we reported the presence of anti-idiotypic antibodies (anti-Id) specific to autoantibodies against GAD65 (GAD65Ab) in healthy individuals while the activity of anti-Id directed to GAD65Ab in T1D patients was significantly lower. These anti-Id recognize the antigen binding site of GAD65Ab, thus preventing their binding to GAD65. Here we characterized the IgG subclass profile of these ant
Several physics courses are given at Lund Institute of Technology. In the basic courses on ray and wave optics, holography has played an important role both in stimulating the students to curiously investigate the optical world and as an important visualisation of some obvious and interesting parts of the courses. To meet the need for basic laboratory experience, a holographic laboratory has been
We investigated the quality of life (QoL) of newly diagnosed persons with cancer aged 65 years at baseline and 3 months after, in relation to age, contact with the healthcare system, activities of daily living, hope, social network and support using the European Organization for Research and Treatment of Cancer QLQ-C30, Katz ADL, Nowotny's Hope Scale, and the Interview Schedule for Social Interact
The Chemotaxis Inhibitory Protein of Staphylococcus aureus (CHIPS) binds and blocks the C5a receptor (C5aR) and formyl-peptide receptor (FPR). This way, CHIPS is a potent inhibitor of the immune cell recruitment associated with inflammation. Truncation of the protein and the introduction of mutations, shifts the expression towards the insoluble fraction of Escherichia coli, whereas the wild-type p
The lifetimes of three short-lived levels belonging to the 4f(9) 6p configuration and of two long-lived levels of the 4f(9) 5d configuration of Dy iii have been measured for the first time using time-resolved laser-induced fluorescence techniques. They are in good agreement with theoretical values calculated within the framework of a pseudo-relativistic configuration interaction approximation. Usi
Aim: This study aims to investigate cardiac structure and function in patients with asymptomatic primary hyperparathyroidism (pHPT) and if there is any relation to severity regarding serum levels of calcium (Ca) and parathyroid hormone. Methods and Results: We consecutively included 50 patients (mean age 62.9 +/- 11 years, 45 women) with clinically diagnosed pHPT. We prospectively recruited 50 hea
Purpose: The purpose of the study was to identify serum microRNAs providing a link between male subfertility and metabolic syndrome (MetS) and validate their diagnostic potential. Methods: Sera were analyzed for fertility and MetS-related parameters in subfertile men (n = 79) and controls (n = 38). Literature review identified miR-155-5p, miR-122-5p, miR-200a-3p, and miR-200c-3p which previously w
We investigated the role of the major histocompatibility complex (MHC) region in the specificity of autoimmunity by analysing specifically the development of sialadenitis, but also insulitis, nephritis and autoantibody production in autoimmune-prone nonobese diabetic (NOD) mice where the MHC H2g7 haplotype had been exchanged for the H2q (NOD.Q) or H2p (NOD.P) haplotype. The exchange of H2 haplotyp
Goodpasture disease (GP) is defined by the presence of anti-glomerular basement membrane (anti-GBM) antibodies and rapidly progressive glomerulonephritis. Besides anti-GBM, many patients with GP produce anti-neutrophil cytoplasmic antibodies (ANCA). For elucidation of the pathophysiologic significance of ANCA in this setting, epitope and antigen specificity of the anti-GBM antibodies and antigen s
Steady-state absorption and femtosecond time-resolved spectroscopic studies have been carried out on astaxanthin dissolved in CS2, methanol, and acetonitrile, and in purified alpha-crustacyanin. The spectra of the S-0 -> S-2 and S-1 -> S-n transitions were found to be similarly dependent on solvent environment. The dynamics of the excited-state decay processes were analyzed with both single wavele
