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This study investigated the possibilities of identifying leading objective indicators of safety across shipping organisations. Leading objective indicators of safety are safety culture related metrics that are statistically correlated with safety performance data which enables a more proactive approach to safety management. The conclusion was that no indicators could be identified, at least no
Syftet med denna studie är att undersöka fyra nutida pianopedagogers syn på hur Frédéric Chopins pianometodik har utvecklats från kompositörens tid fram till nutid. Litteraturen som används för denna studie fokuserar på Chopins tankar om undervisning, Chopin-spel under olika tider, samt traditionsöverföring. Studien baseras på personliga intervjuer och en kvalitativ metod. Data samlas in genom intTitle: "Clever, but not Chopinesque" - A study of four contemporary piano pedagogues’views on Frédéric Chopin’s piano method through the years The purpose of this study is to investigate four contemporary piano pedagogues’ views on how Frédéric Chopin’s pedagogical piano method has developed from the time of the composer to the present day. The literature used for this study focused on C
Alla människor har ett värde som ligger i deras egenskap av att vara just människor. Men att vara människa är inte vad vi aktivt blir definierade som utan i första hand kan identiteter såsom ”elev” komma. Syftet med min uppsats är att undersöka huruvida den svenska grundskolan har en fullständig potential till att respektera sina elevers människovärde trots att de främst blir sedda som elever. FörEvery human being has a value in itself solely on the ground that they are human beings. But a human being is not what you are first and foremost defined as, but rather, for example a “pupil”. The purpose of this essay is to examine whether the Swedish elementary school has the full potential of respecting its’ pupils’ human worth. In order to achieve this I have intertwined threads from philosoph
This essay is going to bring up the terms of adaptation, mainly from book to film and the genre of vampire movies. With the book Låt den rätte komma in and the movie with the same name, I have made an analyzes based on founding out why Tomas Alfredson, the director of the movie cut out some important details from the book while making the movies script together with John Ajvide Lindquist, the auth
Området svensk modehistoria växer mer än någonsin tidigare, men det är fortfarande en liten och sårbar miljö. Få forskare ägnar sig åt modehistoria som sitt huvudsakliga expertområde. Modehistoria är ett relativt nytt forskningsområde med rötter i etnologi, konsthistoria och museiverksamhet. Idag finns det ett svenskt nätverk för modehistoria, men miljön behöver stärkas genom doktorandprojekt och The field of Swedish fashion history is expanding more than ever before, but it remains a small and vulnerable environment. Few researchers devote themselves to fashion history as their main area of expertise. Fashion history is a relatively new field of research with roots in ethnology, art history, and museums. Today, there is a Swedish fashion history network, but the environment needs to be
Sammanfattning Uppsatsens titel: Informationshypotesen - Ger förändringar av utdelningar någon information om framtida vinster? Seminariedatum: 2008-02-04 Ämne/Kurs: NEKK01 – Examensarbete kandidatnivå 15hp Författare: Stefan Setterlund Handledare: Erik Norrman Fem nyckelord: The information content of dividends, informationshypotesen, utdelningar, effektiva marknader, vinster. Syfte: Syftet med d
Innate lymphoid cells (ILCs) are a newly discovered subset of immune cells that promote tissue homeostasis and protect against pathogens. ILCs produce cytokines also produced by T lymphocytes that have been shown to affect atherosclerosis, but the influence of ILCs on atherosclerosis has not been explored. Approach and Results-We demonstrate that CD25+ ILCs that produce type 2 cytokines (ILC2s) ar
Background and Aim: An abnormal immune response to intestinal bacteria has been observed in Crohn's disease (CD). Clostridium difficile infection incidence and severity are increased in CD, but reports on the humoral response have provided conflicting results. We aimed to shed light on the possible role of C. difficile in CD pathogenesis by paying attention to the influence of immunomodulatory tre
Theory predicts democracy should reduce corruption. Yet, scholars have found that while corruption is low at high levels of democracy, it is high at modest levels, as well as low when democracy is absent. A weakness of studies that aim to explain this inverted curvilinear relationship is that they do not disaggregate the complex concepts of democracy and corruption. By contrast, this paper disaggr
Background: The optimal surgical excision margins are uncertain for patients with thick (>2 mm) localised cutaneous melanomas. In our previous report of this multicentre, randomised controlled trial, with a median follow-up of 6·7 years, we showed that a narrow excision margin (2 cm vs 4 cm) did not affect melanoma-specific nor overall survival. Here, we present extended follow-up of this cohort.
Primordial black holes formed through the collapse of cosmological density fluctuations have been hypothesized as contributors to the dark matter content of the Universe. At the same time, their mergers could contribute to the recently observed population of gravitational-wave sources. We investigate the scenario in which primordial black holes form binaries at late times in the Universe. Specific
Over the last decade, Unmanned Aerial Vehicles (UAVs) have been used for monitoring construction and operation of civil infrastructure, as well as industrial facilities and power plants. Their operational simplicity along with time-and-cost-related benefits have already rendered them attractive for structural surveying. Nevertheless, the field of UAV research currently lacks a targeted employment
The β-catenin/Wnt signaling pathway plays an important role in all stages of T cell development. Nemo-like kinase (NLK) is an evolutionary conserved serine/threonine kinase and a negative regulator of the Wnt signaling pathway. NLK can directly phosphorylate histone deacetylase 1 (HDAC1), as well as T cell factor/lymphoid enhancer-binding factor (TCF/LEF), causing subsequent repression of target g
Platelets are the primary cellular mediators of hemostasis and this function firmly acquaints them with a variety of inflammatory processes. For example, platelets can act as circulating sentinels by expressing Toll-like receptors (TLR) that bind pathogens and this allows platelets to effectively kill them or present them to cells of the immune system. Furthermore, activated platelets secrete and
Sterile liver inflammation and fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 inflammatory responses have been reported to contribute to liver pathology. However, the mechanisms controlling the balance between these responses are largely unknown. Natural killer T (NKT) cells can be activated to rapidly secrete cytokines and chemokines associated w
Staphylococcus aureus is a prominent human pathogen. Here we report that intact S. aureus bacteria activate the contact system in human plasma in vitro, resulting in a massive release of the potent proinflammatory and vasoactive peptide bradykinin. In contrast, no such effect was recorded with Streptococcus pneumoniae. In the activation of the contact system, blood coagulation factor XII and plasm
Therapeutic antibodies are the fastest growing class of drugs but suffer from a crowded target-space where many antibodies, against a few targets, are developed in parallel. The aim of this thesis is to find methods to enable discovery of novel antibody-target combinations and thereby increase the target-space. A strategy to achieve this is to use phage display antibody libraries and selection on
There is a clinical need for improved wound treatments that prevent both infection and excessive inflammation. TCP-25, a thrombin-derived peptide, is antibacterial and scavenges pathogen-associated molecular patterns (PAMPs), such as lipopolysaccharide, thereby preventing CD14 interaction and Toll-like receptor dimerization, leading to reduced downstream immune activation. Here, we describe the de
The discovery, in 2004, of extracellular traps released by neutrophils has extended our understanding of the mode of action of various innate immune cells. This fascinating discovery demonstrated the extracellular trapping and killing of various pathogens by neutrophils. During the last decade, evidence has accumulated showing that extracellular traps play a crucial role in the defence mechanisms
