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The role of T cells in the mouse collagen-induced arthritis (CIA) model for rheumatoid arthritis is not clarified, and different results have been reported concerning the role of CD4 and CD8 T cells. To address this issue, we have investigated B10.Q mice deficient for CD4 or CD8. The mice lacking CD4 were found to be less susceptible to disease, but not completely resistant, whereas the CD8 defici

This study presents a thermodynamically consistent continuum damage model for fiber-based materials that combines elastoplasticity and damage mechanisms to simulate the nonlinear mechanical behavior under in-plane loading. The anisotropic plastic response is characterized by a non-quadratic yield surface composed of six sub-surfaces, providing flexibility in defining plastic properties and accurac

The principal noise source for a jet engine is associated with the jet exhaust. The acoustical field that is generated by a jet engine before the take-off is considered. The turbulent jet and the mixing of the hot exhaust gas with the cold surrounding air forms an acoustical source. The compressible Navier-Stokes equations describe both flow field as well as sound generation. The acoustic theory u

This paper presents a pilot study on the prosodic marking of a contrastive topic in Southern Swedish. A test sentence was elicited in three experimental conditions: initial focus; final focus; contrastive topic (initial word) plus focus (final word). F0 patterns were analysed in recordings of 10 speakers. A majority of the speakers distinguished clearly between the conditions, but speakers employe

There are a number of interpretations of the concept “integration” in Product Development (PD). Different sources tend to use different terminologies for describing the same phenomenon of integration, or use the same term for different purposes. This paper strives to capture the essence of the concept of “integration” within a product development project by looking for what is integrated and how i

Purpose: The aim of this study is to explore teachers’ experience and understanding of classroom communication after participating in a speech-language pathologist (SLP) led in-service training on classroom communication. Method: This qualitative study used a focus group approach to explore how teachers describe their classroom communication. Twenty primary-school teachers participated. Thematic a

Topology optimization is used to design phononic bandgap materials that are tunable by mechanical deformation. A periodic media is considered, which due to the assumption of length scale separation, allows the dispersion relations to be obtained by analyzing a single unit cell subjected to Floquet–Bloch boundary conditions. A finite macroscopic deformation is applied to the unit cell to affect its

Proteomics Data Collection (ProDaC) is an EU-funded Coordination Action within the 6th framework programme. It aims to simplify the publication, dissemination and utilization of proteomics data by establishing standards that will support broad data collection from the research community. As a part of ProDaC, regular workshops are organized on a half-yearly basis to enable communication and discuss

Purpose: An elevated sense of vocal effort due to increased vocal demand is frequently reported by patients with voice disorders. However, effects of vocal warm-up on self-assessed vocal effort have not been thoroughly examined. A recently developed version of the Borg CR-10 Scale facilitates vocal effort assessments, following different vocal warm-up tasks. Methods: Effects of a short (5 min) voc

The Secret Diaries of Miss Anne Lister (2010) and Gentleman Jack (2019–2022) are both television dramas based on the private journals of Anne Lister (1791–1840). The diaries were not only partly written in code but make use of idiosyncratic terms, and  the two adaptations deal in different ways with the language used in the diaries. This essay examines the language of Anne Lister’s diaries and com

For the first time, an IP created in China has become a global consumer craze. And it happened entirely without central planning.

Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in vaccination, autoimmunity, and cancer. Here, we use fate mapping, functional analyses, and comparative cross-species transcriptomics to show that RORγt+ DCs are a co

This chapter, authored by Oksana Mont, explores the sharing of idle household goods through tool and toy libraries, contrasting them with traditional book libraries funded by local governments. Unlike book libraries, tool and toy libraries face challenges in developing sustainable business models while maintaining community-focused values. Drawing from the "Urban Sharing: Sustainability and Instit

Recognizing individual variability is essential for developing targeted, personalized medical interventions. Vocal fatigue is a prevalent symptom and complaint among occupational voice users, but its identification has yielded mixed results. Vocal fatigue is a complex issue with heterogeneous biophysiological responses to vocal demands among individuals. This research aims to classify individuals

Background: Older adults are underrepresented in suicide prevention research, even though suicide rates are higher in this age group (65+) than in any other age group in many countries worldwide. There are few clinical intervention studies that target this age group. A promising preventive intervention is the Attempted Suicide Short Intervention Program (ASSIP). Given differences in suicidal behav