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In many reports the improvements of the actors in the construction sector have been requested. One explicit factor that has been called for is an increase in cooperation and communication between the different actors. The Swedish construction sector in general has not been swift in accepting new process improvements as they have been put forward by academics or government. There are many possible

We need to understand the major signalling events in human B cell differentiation in order to be able to regulate the generation of human antigen specific antibodies. This study has focused on the signalling mechanisms involved in generation of germinal centre reaction and secretion of specific antibodies by human B cells, using different in vitro immunisation technologies. Naive human B cells tha

Nontypeable Haemophilus influenzae (NTHi) is a commensal microbe often isolated from the upper and lower respiratory tract. This bacterial species can cause sinusitis, acute otitis media in preschool children, exacerbations in patients suffering from chronic obstructive pulmonary disease, as well as conjunctivitis and bacteremia. Since the introduction of a vaccine against H. influenzae serotype b

Understanding implications on firm performance from the emergence of Internet of Things (IoT) is critical in order for firms to make rational decisions regarding business model configurations and investments in IoT. The transition between the current state and widespread adoption and diffusion of IoT is expected to be complex, and standardization is one of multiple barriers discussed in research r

Flexible multibody dynamics (FMD) has found many applications in control, analysis and design of mechanical systems. FMD together with the theory of structural optimization can be used for designing multibody systems with bodies which are lighter, but stronger. Topology optimization of static structures is an active research topic in structural mechanics. However, the extension to the dynamic case

Many animals are known to preferentially mate with partners that are dissimilar at the major histocompatibility complex (MHC) in order to maximize the antigen binding repertoire (or disease resistance) in their offspring. Although several mammals, fish or lizards use odour cues to assessMHCsimilarity with potential partners, the ability of birds to assessMHC similarity using olfactory cues has not

Remains of a basilican round church were discovered in 1877–78 in Tønsberg, Norway, and identified as the Premonstratensian monastery church of Saint Olav. The round church has been interpreted as fortified with several floors using Nylars on Bornholm in Denmark as a model – or as symbolic copy of Holy Sepulchre in Jerusalem, although Templar churches have also been mentioned as models. The church

Globally, an enormous number of polluted areas are in need of remediation to prevent adverse effects on health and environment. In situ remediation and especially the monitoring thereof needs further development to avoid costly and hazardous shipments associated with excavation. The monitoring of in situ remediation actions needs easier and cheaper nondestructive methods for evaluation and verific

Sepsis and invasive bacterial infection is a major cause of human disease and death worldwide. Streptococcus pyogenes is one of the major pathogens responsible for bacterial infections, which range from mild to severe and life threatening conditions. S. pyogenes contains a cell wall anchored M protein, which is an important virulence factor that can interact with many cells of the immune system. O

Biological soft tissues exhibit non-linear complex properties, the quantification of which presents a challenge. Nevertheless, these properties, such as skin anisotropy, highly influence different processes that occur in soft tissues, for instance wound healing, and thus its correct identification and quantification is crucial to understand them. Experimental and computational works are required i

Background: Derivatized celluloses, such as methylcellulose (MC) and hydroxypropyl methylcellulose (HPMC), are of pharmaceutical importance and extensively employed in tablet matrices. Each batch of derivatized cellulose is thoroughly characterized before utilized in tablet formulations as batch-to-batch differences can affect drug release. The substitution pattern of the derivatized cellulose pol

Lasers and masers have numerous uses in today’s society. Improving our understanding of the underlying physics and its application is thus of great importance. In this paper, the physics of a three-level maser when treated as a heat-engine was investigated: certain levels were coupled to thermal-reservoirs, effectively allowing for pumping without an external bias. The thermodynamical treatment fo

Vision is often considered to top the hierarchy of the senses, reflected for example in the high relative frequency of vision verbs, in comparison to other perception verbs. Results from some previous studies, however, have shown that there is greater cross-linguistic variation concerning perception language than previously thought, emphasising other sense modalities than vision. This thesis condu

Detta är en kvalitativ studie som avhandlar ämnesintegration och hur det kan tillämpas av lärare i musik och engelska. Den ger även en inblick i hur lärare jobbar med det centrala innehållet i musik, med specifikt fokus på den del som kallas musikens sammanhang och funktion. Fyra lärare med ämneskombinationen musik och engelska har intervjuats. Jag har även gjort litteraturstudier för att få en dj

Human pigmentation is a complex phenomenon commonly believed to serve a photoprotective function through the generation and strategic localization of black insoluble eumelanin biopolymers in sun exposed areas of the body. Despite compelling biomedical relevance to skin cancer and melanoma, eumelanin photoprotection is still an enigma: What makes this pigment so efficient in dissipating the excess

Complement components and their cascade of reactions are important defense mechanisms within both innate and adaptive immunity. Many complement deficient patients still remain undiagnosed because of a lack of high throughput screening tools. Aiming towards neonatal proteome screening for immunodeficiencies, we used a multiplex profiling approach with antibody bead arrays to measure 9 complement pr

To date, there have been several detections of high-mass black hole binaries in both the Milky Way and other galaxies. For some of these, the spin parameter of the black hole has been estimated. As many of these systems are quite tight, a suggested origin of the spin is angular momentum imparted by the synchronous rotation of the black hole progenitor with its binary companion. Using Cygnus X-1, t

Antibody array-based technology is a powerful emerging tool in proteomics, but to enable global proteome analysis, antibody array layouts with even higher density has to be developed. To this end, we have further developed the first generation of a nanoarray platform, based on attoliter sized vials, attovials, which we have characterized and used for the detection of complement factor C1q in human