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Background: The kynurenine pathway enzymes, breaking down tryptophan, are abundant in placental tissue. These metabolites are involved in immunoregulatory mechanisms, although the role of this pathway in pre-eclampsia (PE) has only begun to be characterized. Here, we determined tryptophan and metabolite levels together with the expression of kynurenine pathway enzymes and inflammatory factors in p
Dermatan sulfate epimerase 1 (DS-epi1, EC 5.1.3.19) catalyzes the conversion of d-glucuronic acid to l-iduronic acid on the polymer level, a key step in the biosynthesis of the glycosaminoglycan dermatan sulfate. Here, we present the first crystal structure of the catalytic domains of DS-epi1, solved at 2.4 Å resolution, as well as a model of the full-length luminal protein obtained by a combinati
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include the post-cardiac arrest syndrome, diagnosis of cause of cardiac a
The aim was to evaluate volume, diffusion, and perfusion metrics for better presurgical differentiation between high-grade gliomas (HGG), low-grade gliomas (LGG), and metastases (MET). For this retrospective study, 43 patients with histologically verified intracranial HGG (n = 18), LGG (n = 10), and MET (n = 15) were chosen. Preoperative magnetic resonance data included pre- and post-gadolinium co
Neurotensin regulates both satiety and breast cancer growth in the experimental setting, but little is known about its role in the development of breast cancer or cardiometabolic disease in humans.
Aim: Previous studies evaluating the relationship between sex and post-resuscitation care and outcomes following out-of-hospital cardiac arrest (OHCA) are conflicting. We investigated the association between sex and outcomes as well as neurodiagnostic testing in a prospective multicenter international registry of patients admitted to intensive care units following OHCA. Methods: OHCA survivors enr
Agriculture is key to sustainable development globally – particularly incountries where agriculture both accounts for most of the land use andprovides a livelihood for most of the population. We map out a collaborativeresearch agenda aimed at tackling the urgent but poorly understood issue ofthe role of farmer organisations in overcoming political barriers tosustainable and inclusive agricultural
AI-kommissionen föreslår 75 steg för att Sverige ska stärkas genom AI. Många av förslagen är välriktade, inte minst på utbildnings- och forskningsområdet. Det krävs tunga AI-investeringar framöver, men de får inte bara rikta in sig på teknik skriver bland annat Virginia Dignum, Professor Responsible Artificial Intelligence Umeå Universitet, Jonas Ivarsson, professor i informatik vid Göteborgs uni
OBJECTIVE: Previous literature has suggested that identifying putative differences in health care seeking patterns before death by suicide depending on age and gender may facilitate more targeted suicide preventive approaches. The aim of this study is to map health care utilisation among individuals in the two years prior to suicide in Sweden in 2015 and to examine possible age and gender differen
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity. It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority of SCLCs exhibit neuroendocrine features, an important subset of tumors lacks these properties. Genomic profiling of SCLC reveals genetic instability, almost universal inactivation of the tumor suppressor genes TP5
Background: Cardiac arrest (CA) represents the third leading cause of death worldwide. Among patients resuscitated and admitted to hospital, death and severe neurological sequelae are frequent but difficult to predict. Blood biomarkers offer clinicians the potential to improve prognostication. Previous studies suggest that circulating non-coding RNAs constitute a reservoir of novel biomarkers. The
BACKGROUND: Pre-hospital circumstances, cardiac arrest characteristics, comorbidities and clinical status on admission are strongly associated with outcome after out-of-hospital cardiac arrest (OHCA). Early prediction of outcome may inform prognosis, tailor therapy and help in interpreting the intervention effect in heterogenous clinical trials. This study aimed to create a model for early predict
OBJECTIVES: To explore treatment outcomes preferred by patients with early rheumatoid arthritis (RA) and how these change throughout the early disease stage across three European countries. METHODS: A longitudinal, qualitative, multicentre study was conducted in Belgium, the Netherlands and Sweden. 80 patients with early RA were individually interviewed 3-9 months after treatment initiation and 51
Diagnosing sepsis in critical care remains a challenge due to the lack of gold-standard diagnostics. Calprotectin (S100A8/A9) has been proposed as a diagnostic marker to identify sepsis in critically ill patients. This study evaluated the diagnostic performance of calprotectin and C-reactive protein (CRP) to distinguish between sepsis and non-sepsis on intensive care unit (ICU) admission. Admissio
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations (CoSTR) pubished by the International Liaison Committee on Resuscitation (ILCOR). The topics cover
19MOD2_Nordrum & Cimbritz_inspirationskonferens_LN LTH:s 13:e Pedagogiska Inspirationskonferens, 4 december 2025 Abstract— In this roundtable, we will discuss the role of the kappa, the framing text in a compilation thesis, in STEM doctoral education. Based on two runs of the new course Framing your research – thesis frames and knowledge contribution for doctoral students at LTH and a focus group
https://www.lth.se/fileadmin/cee/genombrottet/konferens2025/D2_Nordrum_Cimbritz.pdf - 2026-06-09
8bMOD_Thoni_2025_LTH_Conference_final LTH:s 13:e Pedagogiska Inspirationskonferens, 4 december 2025 Abstract—Education for Sustainability (EfS) has been promoted by the United Nations for more than a decade and is something that Lund University values highly. Operationa- lization of EfS requires time, resources, and training for educators. However, educators are increasingly under pressure and hav
https://www.lth.se/fileadmin/cee/genombrottet/konferens2025/D4b_Thoni.pdf - 2026-06-09
MolinaBesch_Olsson2016 LTHs 9:e Pedagogiska Inspirationskonferens, 15 december 2016 Abstract — In a world where technical knowledge gets outdated in an ever increasing speed, it is important that engineering education provides students not only with broad technical competences but also with so-called soft skills such as communications skills, leadership skills and team-working skills. When it come
https://www.lth.se/fileadmin/lth/genombrottet/konferens2016/22_Molina-Besch_Olsson.pdf - 2026-06-09
Upptecknaren 2017 FOLKLIVSARKIVET UPPTECKNAREN 2017 Upptecknaren 2017 FOLKLIVSARKIVET | LUNDS UNIVERSITET Förord Att skvallra och sprida rykten om kungen – pågående forskning om medierade skandaler Mia-Marie Hammarlin och Lars-Eric Jönsson (sid. 4) Nyhetskonsumtion Anton Öhman (sid. 6) Fästingar – biologi och folktro Göran Sjögård (sid. 11) Frågelistverksamheten vid Folklivsarkivet Gabi Louisedott
https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/upload/Upptecknaren/Upptecknaren_2017.pdf - 2026-07-16
Bookphoria with Victoria - On Education - The Raoul Wallenberg Institute of Human Rights and Humanitarian Law Skip to content Search for: Search Button Home About Us Who We Are Our History About Raoul Wallenberg Our Theory of Change Staff Opportunities Annual Reports Whistleblower Our work What we do Multi-Disciplinary Research Higher Education Strategic Advice and Analysis Outreach Evaluation of
https://rwi.lu.se/blog/bookphoria-with-victoria-on-education/ - 2026-07-16
