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Familial isolated GH deficiency type II (IGHD-II) is an autosomal dominant disorder that has been previously shown in some patients to be caused by heterogeneous GH gene defects that affect GH messenger RNA (mRNA) splicing. We report here our finding of multiple G-->A transitions of the first base of the donor splice site of IVS 3 (+ 1G-->A) in IGHD II subjects from three nonrelated kindreds from
BACKGROUND: Despite oral anticoagulation, patients with atrial fibrillation (AF) remain at risk of ischemic stroke and systemic embolism (SE) events. For patients whose residual risk is sufficiently high, additional therapies might be useful to mitigate stroke risk. METHODS AND RESULTS: Individual patient data from 5 landmark trials testing oral anticoagulation in AF were pooled in A Collaboration
Pneumococcal surface protein A (PspA) is an important virulence factor in Streptococcus pneumoniae that binds to lactoferrin and protects the bacterium from the bactericidal action of lactoferricins—cationic peptides released upon lactoferrin proteolysis. The present study investigated if PspA can prevent killing by another cationic peptide, indolicidin. PspA-negative pneumococci were more sensiti
The objective of this paper is to demonstrate the legal implications for asylum-seekers flowing from their resort to falsified documents as a method of gaining access to the territory of asylum countries. Article 31(1) of the Refugee Convention is supposed to act as a shield against punishment for illegal entry. However, the paper identifies four issues relating to the application of Article 31 wh
A well defined set of design criteria is of great importance in the process of designing brain machine interfaces (BMI) based on extracellular recordings with chronically implanted micro-electrode arrays in the central nervous system (CNS). In order to compare algorithms and evaluate their performance under various circumstances, ground truth about their input needs to be present. Obtaining ground
Climate change affects timing of reproduction in many bird species, but few studies have investigated its influence on annual reproductive output. Here, we assess changes in the annual production of young by female breeders in 201 populations of 104 bird species (N = 745,962 clutches) covering all continents between 1970 and 2019. Overall, average offspring production has declined in recent decade
This is the first attempt to budget average current annual carbon (C) and associated greenhouse gas (GHG) exchanges and transfers in a subarctic landscape, the Lake Torneträsk catchment in northern Sweden. This is a heterogeneous area consisting of almost 4000 km2 of mixed heath, birch and pine forest, and mires, lakes and alpine ecosystems. The magnitudes of atmospheric exchange of carbon in the
Is the oncogene MYC upregulated or hyperactive? In the majority of human cancers, finding agents that target c-MYC has proved difficult. Here we report specific bacterial effector molecules that inhibit cellular MYC (c-MYC) in human cells. We show that uropathogenic Escherichia coli (UPEC) degrade the c-MYC protein and attenuate MYC expression in both human cells and animal tissues. c-MYC protein
Sasiya kom från Thailand för att läsa en master i humanekologiMeet Sasiya from Thailand.
Arbetsprocess kandidatarbete för civilingenjörer | exjobb_externa Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas
F11f ARKIV: SKÅNES MUSIKSAMLINGAR (Folklivsarkivet med Skånes musiksamlingar) Serierubrik: Video/Film (VF) Signum: F11f Löpnr Volym Tid Innehåll VF 1-VF 255 1983 – 2013 1972 – 2004 VF 1-VF 91. Video/film från fältarbeten utförda av medarbetare vid Folklivsarkivet med Skånes musiksamlingar. Även av enskilda arkivbildare och externa fältarbetare som Christer Lundh och Börje Wallin (folkdans) m fl. V
https://www.folklivsarkivet.lu.se/fileadmin/user_upload/folklivsarkivet/Musiksamlingarna_webb/Dokument/F11f.pdf - 2026-07-20
Microsoft Word - Mastersuppsatsriktlinjer 2025 Historiska institutionen Riktlinjer för uppsatsarbete på masterprogrammet - 2 - Innehåll ALLMÄNNA RIKTLINJER ................................................................................................... 3 UPPSATSKURSENS FUNKTION OCH MÅL .................................................................................... 3 ATT SKRIVA OCH VENTILER
Utbildning | Matematikcentrum Hoppa till huvudinnehåll Den här webbplatsen använder cookies för att förbättra användarupplevelsen. Genom att fortsätta använda webbplatsen samtycker du till att cookies används enligt vår cookie-policy (på LTH:s webbplats) . Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte stängas av i våra system. Dessa cookies lag
https://www.maths.lu.se/utbildning/ - 2026-07-20
BackgroundPrimary brain tumors, in particular glioblastoma (GBM), remain among the most challenging cancers. Like most malignant tumors, GBM is characterized by hypoxic stress that triggers paracrine, adaptive responses, such as angiogenesis and macrophage recruitment, rescuing cancer cells from metabolic catastrophe and conventional oncological treatments. The unmet need of strategies to efficien
Background: Emerging evidence indicates that estrogen receptor-low (ER-low)/human epidermal growth factor receptor 2 negative (HER2-) breast cancer (BC) may more closely resemble ER-negative (ER-zero, < 1%) rather than ER-positive disease in terms of biological and clinicopathological characteristics. In Sweden, ER-low (ER 1–9%) BC is managed as triple-negative breast cancer (TNBC) and is thus eli
BACKGROUND: Sexual violence against older adults in humanitarian settings is poorly documented, leading to gaps in prevention and delivery of support services. This study aimed to document differences in assault characteristics between younger and older adults, by sex and displacement and disability status and region. METHODS: This retrospective, descriptive observational, multi-country study incl
Microsoft Word - Riktlinjer Kandidatuppsatser VT 2017.doc Historiska institutionen Riktlinjer för uppsatsarbete på kandidatkursen - 2 - Innehåll ALLMÄNNA RIKTLINJER ............................................................................................... 3 UPPSATSKURSENS FUNKTION OCH MÅL .............................................................................3 Målet med uppsatskursen är
https://www.historiska.lu.se/media/utbildning/dokument/kurser/HISK01/20171/Riktlinjer_Kandidatuppsatser_VT_2017.pdf - 2026-07-21
Teknikavtalet Unionen/Sveriges Ingenjörer/Ledarna 1 april 2025–31 mars 2027 Kollektivavtal mellan Teknikarbetsgivarna och Unionen, Sveriges Ingenjörer samt Ledarna I äldre avtalstexter förekommer organisationernas tidigare namn eller förkortningar. Sveriges Verkstadsförening (VF) = Teknikarbetsgivarna Svenska Arbetsgivareföreningen (SAF) = Svenskt Näringsliv Svenska Industritjänstemannaförbundet (
High hypoxia-inducible factor-2 alpha (HIF-2 alpha) protein levels predict poor outcome in neuroblastoma, and hypoxia dedifferentiates cultured neuroblastoma cells toward a neural crest-like phenotype. Here, we identify HIF-2 alpha as a marker of normoxic neural crest-like neuroblastoma tumor-initiating/stem cells (TICs) isolated from patient bone marrows. Knockdown of HIF-2 alpha reduced VEGF exp
