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Obesity is a complex disease with multiple well-defined risk factors. Nevertheless, susceptibility to obesity and its sequelae within obesogenic environments varies greatly from one person to the next, suggesting a role for gene x environment interactions in the etiology of the disorder. Epigenetic regulation of the human genome provides a putative mechanism by which specific environmental exposur
Sweden was the first country in the world to introduce rules on transparency in public activities - the principle of public access to official records was introduced as early as 1766 as part of the Freedom of the Press Act of 1766. This legislation, which was unique at the time, has since meant that Sweden has had public access to official records and transparency as the main rule for public activ
This review presents the status and outlook for shared energy systems (SES) and fifth-generation district heating and cooling (5GDHC). It provides an overview of the technical and functional knowledge encompassing design and development, operational and system architecture, and control and decision support systems of these technologies. The review also presents different tools and models found in
Telecommunications industries are investing tremendously to meet the ever-increasing demands for higher data rates and capacity. In particular to develop standardization for 5G, which is expected around 2020. The existing spectrum for traditional mobile networks is limited to highly occupied bands at microwave frequencies below 6 GHz. It is expected that 5G will use millimeter-waves to enable high
This research platform gathers scholars from a number of disciplines to interrogate the complex ideological, historical, and practical interactions between Christianity and nationalism. The platform understands both terms broadly; it investigates various forms of Christianity and different shapes of nationalism — through political, economic, sociological, historical, theological and philosophical
Analysis of the debates in the Swedish press concerning the controversies around the open-air art exhibition "Sculptura-97" in Falkenberg.
Human cathelicidin antimicrobial protein hCAP18/LL-37 is an effector molecule of the nonspecific innate immune system. hCAP18/LL-37 is present in leukocytes and is expressed in skin and other epithelia, where it is upregulated in association with inflammation and injury. In addition, antimicrobial proteins including cathelicidins have been proposed to play a role in the nonspecific defense against
Monoamine and acetylcholine neurotransmitters from the autonomic nervous system (ANS) regulate insulin secretion in pancreatic islets. The molecular mechanisms controlling neurotransmitter signaling in islet β cells and their impact on diabetes development are only partially understood. Using a glucose-intolerant, MafA-deficient mouse model, we demonstrate that MAFA controls ANS-mediated insulin s
Forskningsämnet förlags- och bokmarknadskunskap studerar förlag, bokmarknad, försäljningssystem, digitalisering av böcker, läsning, litteraturens plats i samhället samt sociala, ekonomiska och praktiska aspekter av böcker och litteratur. Ämnets frågor, metoder och teorier härstammar från en rad olika discipliner, exempelvis litteraturvetenskap, bokhistoria och kulturstudier, digital humaniora, medPublishing Studies as a research field include publishers, book markets, sales systems, book digitization, reading, the role of literature in society, and the social, economic, and practical aspects of books and literature. Its topics, methods and theories originate from various disciplines, including comparative literature, book history, cultural studies, digital humanities, media and communicati
Anders Bjartell är forskargruppsledare för den här forskargruppenTranslational research on prostate cancer: Identification of molecular targets for development of new therapies in chemo- and hormone resistant prostate cancer. This includes: 1) In vitro studies and animal models. 2) Development and validation of biomarkers in tissue, blood and urine including circulating tumor cells. 3) Biobanking. 4) Clinical studies on imaging biomarkers for prognosis, predict
Näthinnan (Retina) är en del av det centrala nervsystemet och består till största delen av specialiserade nervceller. Vid degenerativ näthinnesjukdom, t.ex retinitis pigmentosa, åldersrelaterad makuladegeneration, näthinneavlossning och glaukom förstörs nervceller vilket resulterar i idag icke behandlingsbar synnedsättning. Traditionellt undersöks ofta sjukdom och behandling inom CNS experimentellTraditionally, experimental neuronal research is conducted on single cells after disruption of the tissue. A more pertinent approach to the complex CNS is to consider cells, extracellular matrix, and cell junctions as a tissue continuum through which mechanical and biochemical information is bidirectionally communicated. Our research is focused on retinal cell interactions in health and disease, a
Avdelningen består av etnologi (se ämnesbeskrivning nedan)The research in ethnology has two primary orientations, both of which work with historical as well as contemporary perspectives. The first orientation focuses on practices of everyday life – that is to say the study of what people do in their daily lives and how such activities constitute the grounds for different cultural patters of thought and societal values. Research in this area of study prob
Botswana has figured widely as the exceptional African growth success story and has been frequently cited in scholarship that supports the view that African and other less developed economies are capable of rapid economic growth as long as the internal institutional framework and development policies are right. A shortcoming of the literature on African economic performance to date is that it has
We examine energy and CO2 intensities (energy use / GDP and CO2 emissions / GDP) in Sweden and Spain during the last two hundred years. The first aim is to establish reliable and comparable time-series. We include all energy that involves some human effort in its capture. Therefore, not only do we include modern energy carriers such as coal, oil, and electricity, but also we aim to account for fir
The building sector is responsible for more than 40% of the energy use and 32% of carbon dioxide emissions in the European Union (EU). Previous research has shown that the present rate of energy retrofit and refurbishment in Europe is far below (< 50%) than that is required to meet the EU’s building related energy efficiency goals for 2020.Appropriate policy interventions for deep renovation is pe
