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Recombinant lentiviral vectors (rLV) are powerful tools for gene transfer to the central nervous system (CNS) and hold great potential as a therapeutic gene therapy strategy for neurological disorders. Recent data indicate that rLVs are suitable for functional studies in the CNS by over expression or knock down of specific proteins. Based on a variety of lentiviruses species, different vector syst
A shorted pin circular axe-shaped antenna is analyzed for compact and dual band applications. Removing two symmetric arc-shaped areas from a simple circular patch lengthens the current path thus reduces the antenna size. Embedding and adjusting a shorting pin further shifts the resonance to a lower frequency and excites another high order mode. The frequency ratio varies between 1.639 ∼ 2.616. The
We show that an ultraviolet prepulse significantly enhances the water-window x-ray emission and brightness for a droplet-target laser plasma. By combining a 65 mJ, 120 ps, lambda = 532 nm main pulse with an up to 3 mJ prepulse, the emitted x-ray photon flux may be increased more than eight times. The resulting C VI lambda = 3.37 nm line emission is more than 3 x 10(12) photons/sr . pulse, correspo
We propose an integrated framework for the design of SOC test solutions, which includes a set of algorithms for early design space exploration as well as extensive optimization for the final solution. The framework deals with test scheduling, test access mechanism design, test sets selection, and test resource placement. Our approach minimizes the test application time and the cost of the test acc
A system arising in the modeling of oil-recovery processes is analyzed. It consists of a hyperbolic conservation law governing the saturation and an elliptic equation for the pressure. By an operator splitting approach, an approximate solution is constructed. For this approximation appropriate a-priori bounds are derived. Applying the Arzela-Ascoli theorem, local existence and uniqueness of a clas
The Transplantation Society, in collaboration with the Canadian Society of Transplantation, organized a forum on education on ODT for schools. The forum included participants from around the world, school boards, and representatives from different religions. Participants presented on their countries' experience in the area of education on ODT. Working groups discussed about technologies for educat
The introduction of Rituximab has greatly improved therapeutic options for patients with B-cell non-Hodgkin lymphoma (B-NHL). However, a substantial fraction of patients with aggressive B-NHL fails first-line therapy, and most patients with relapsing indolent B-NHL eventually acquire Rituximab resistance. Molecular understanding of the underlying mechanisms facilitates the development of pharmacol
Investigation of the differential operators with the generalized coefficients having singular support on a disjoint set of points requires the consideration of the distribution theory with the set of discontinuous test functions. Such a distribution theory for test functions having discontinuity at one point is developed. A four-parameter family of Schrodinger operators, formed by the operators wi
In this paper a robust method is presented for the combined design of STATCOM and Power System Stabilizer (PSS) controllers in order to enhance the damping of the low frequency oscillations in power systems. The combined design problems among PSS and STATCOM internal ac and dc voltage controllers has been taken into consideration. The equations that describe the proposed system have been linearize
Hand osteoarthritis (OA) is a common form of OA, for which education and exercise are considered the first-line treatment. The aim of the present study was to examine pain and perceived hand function in participants following 3 months of digitally delivered first-line treatment for hand OA. Three-hundred-and-seventy-nine of 846 participants with clinical signs and symptoms of hand OA completed the
Reducing the heterogeneity of technical lignin is essential to obtain predictable and high-performance polymeric materials that are suitable for high-value applications. Organic solvents with different polarities and solubilities can be used to fractionate lignin and reduce the complexity and diversity of its chemical structure. Among the various solvents and solvent mixtures, acetone-water mixtur
Develops the Black feminist concept of reproductive justice further in critical dialogue.Includes case studies and perspectives from Sweden, Nicaragua, Poland, Taiwan.Focuses on the historical and contemporary interplay between the state and the pro- abortion/anti-abortion movements.
The introduction of laminated timber, glulam being an example, allowed many of the disadvantages associated with solid wood to be overcome. The disadvantages in question are mainly those related to the size and shape limits of structural elements made of solid wood and to the large variability in such material properties of solid wood as strength and stiffness.In the present thesis, which comprise
Background: Biologgers have contributed greatly to studies of animal movement, behaviours and physiology. Accelerometers, among the various on-board sensors of biologgers, have mainly been used for animal behaviour classification and energy expenditure estimation. However, a general principle for the combined sampling duration and frequency for different taxa is lacking. In this study, we evaluate
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function and may be characteristic of early pulmonary disease. While standard indices like spirometry, body plethysmography, and blood gases have been utilized to assess lung function, they do not provide adequate information on regional ventilatory distribution nor function assessments of ventilation during the respira
Our aim was to compare the inter-rater agreement about transvaginal ultrasonography (TVS) with magnetic resonance imaging (MRI) with regard to diagnosing adenomyosis and for assessing various predefined imaging features of adenomyosis, in the same set of women. The study cohort included 51 women, prospectively, consecutively recruited based on a clinical suspicion of adenomyosis. MRIs and TVS vide
Background: We aim to estimate population-attributable fractions (PAF) for 13 comorbidities potentially predisposing to hepatobiliary cancer of hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cancers of the intrahepatic and extrahepatic bile ducts (ICC and ECC), and ampullary cancer. Methods: Patients were identified from the Swedish Inpatient Register from 1987 to 2018 and cancers from
Lung neuroendocrine neoplasms (NEN) are a heterogeneous population of neoplasms with different pathology, clinical behavior, and prognosis compared to the more common lung cancers. The diagnostic work-up and treatment of patients with lung- NEN has undergone major recent advances and new methods are currently being introduced into the clinic. These Nordic guidelines summarize and update the Nordic
