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This study clarifies when Bayesian analysis provides a practical advantage, particularly in large-area searches, hazardous or inaccessible environments, and low signal-to-noise ratio (SNR) scenarios where direct source approach is not feasible. We present a PyMC-based Bayesian framework for localizing a single unshielded gamma-emitting source and estimating its activity, with the ability to switch
ObjectivesAutoantibodies against tissue transglutaminase (tTG) are serological markers of celiac disease. The aim was to study the applicability of human leukocyte antigen (HLA)-genotyping and tTG autoantibodies in the screening of celiac disease in a longitudinal birth cohort followed to age 15 years.MethodsIncluded were 13,860 HLA-DQ-genotyped children at birth and previously invited to a screen
The fields of cultural tourism and heritage management are gaining attention for their potential to be better linked, particularly in terms of practical applications. This paper proposes a taxonomy of heritage resources and related heritage-based tourism types and their linkages for specific case study areas, building on the established product class approach in cultural tourism studies. The resea
Hazardous situations involving radioactive, chemical, and other dangerous materials pose significant risks to emergency responders. In such situations, robots can support civil forces in reconnaissance and mitigation. However, this requires the development of robotic systems with novel AI-based assistance functions, operation procedures, and raises new ethical and legal questions. To address these
Background: Ageing-in-place policies have increasingly shifted elder care responsibilities onto family members. Among older cohabiting couples, one’s partner’s illness significantly impacts the other’s daily life and well-being.Aim: To explore the responsibilities and strategies of caregiving partners in older cohabiting couples from the perspectives of cohabiting caregivers.Methods: A qualitative
Green ammonia synthesis from nitrogen via photocatalysis and electrocatalysis has emerged as a pivotal research focus in sustainable chemical processes. The efficient catalytic reduction of nitrogen necessitates concurrent nitrogen activation and hydrogen evolution suppression, representing a significant challenge. In this study, CuAu bimetallic-modified TiO2 catalysts were developed and engineere
This article explores the complex relationship between performance programs in higher music education and the evolving demands of current and future professional music scenes. Drawing upon career anchor theory and enactive cognitive science, it introduces a workshop-based framework to support students in reflecting on future working life. The framework decenters ideas of entrepreneurship and marke
It has been a century since the birth of philosopher Gilles Deleuze (1925-95). At his friend’s expense, Michel Foucault once joked, saying that un jour ce siecle sera peut-etre deleuzien: “perhaps one day this century will be known as Deleuzian?” Is there truth to the notion that the present moment expresses something of a “Deleuzian aeon” for the humanities, and what are its ramifications for bib
Complexity and innovation are emerging as fundamental issues for the future of human life and society. To deal with them, different versions of systems thinking have been proposed. However, System-of-Systems (SoS) thinking, based on the biperspectival principle and human reflexivity, has not yet been clearly recognized. The unclear distinction between ‘systems’ and ‘SoS’ thinking often results in
The current paper focuses on the conceptual design and numerical analysis of a four-stage centrifugal pump for the fuel system of a turbofan engine with liquid hydrogen as fuel. Liquid hydrogen is challenging at high pressures due to its special fluid properties. The design condition for the pump is set at take-off, to raise the pressure of liquid hydrogen from 6 bars at the outlet of a low-pressu
Currently, the European Union (EU) is the “green leader”, globally, in adopting policies to support longer product lifetimes. One reason for this state of affairs is that EU Member States are adopting progressive policies, which put pressure on the EU to set EU-wide laws to replace national ones. The main reason for this situation is that national rules may lead to distortions in trade in the EU S
Based on a combination of morphometric analyses, a chloroplast DNA phylogeny, and multivariate analyses of whole genome sequence data from >300 museum samples, we discuss and evaluate the delimitation, taxonomy, and evolution of wild and escaped taxa in Mentha subgen. Mentha, focusing on the northern hemisphere. Thirteen species (Mentha aquatica, M. arvensis, M. australis, M. capensis, M. dahurica
Obesity represents a global health challenge, with a critical and urgent need for long-term, sustainable management strategies. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. At first approved for the treatment of type 2 diabetes mellitus, tirzepatide represents one of the latest clinically approved and commercia
Galactoglucomannan (GGM) has been identified as a valuable resource and can be used in fields such as oxygen barrier films, food coatings or hydrogels. This hemicellulose can be extracted from softwood using steam explosion (STEX) under mild conditions. However, the GGM-solution also contains impurities such as lignin, lignin-carbohydrate complexes, organic acids, and salts, which require further
Although groundwater serves as the predominant source of drinking water across many rural regions and certain urban areas of Rwanda, little is known about this resource. Anthropogenic impacts, such as faecal contamination, as well as geogenic water quality problems, including elevated arsenic, fluoride, iron, and manganese, are among the issues of concern for groundwater quality in Rwanda. Long-te
Conditional knockout mice are commonly used to study the function of specific genes in hematopoiesis. Different promoters that drive Cre expression have been utilized, with the interferon-inducible Mx1-Cre still being the most commonly used “deleter strain” in experimental hematology. However, different pitfalls associated with this system could lead to misinterpretation in functional studies. We
Different functions for the programming of the cross flow in asymmetrical flow field-flow fractionation were studied with the aim to find the flow conditions most suitable for the molar mass distribution analysis of high molecular weight polysaccharides. A mixture of four differently sized pullulans covering the molar mass range 5.8 x 10(3)-1.6 x 106 g mol(-1) were used as a model sample. Two type
