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During memory formation, structural rearrangements of dendritic spines provide a mean to durably modulate synaptic connectivity within neuronal networks. New neurons generated throughout the adult life in the dentate gyrus of the hippocampus contribute to learning and memory. As these neurons become incorporated into the network, they generate huge numbers of new connections that modify hippocampa
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Together with response time the force of responses to stimuli can provide important clues about cognitive and affective processes. However, while there has been much discussion of factors involved in the accurate measurement of response time (RT), key issues and assumptions in assessment of response force (RF) have been far less studied. Here, hierarchical Bayesian analysis is used to examine the
The paper examines the metaphysical ideas employed to embed Hellenistic astrology in an Indian religious and cultural context, relating them to questions of causality, determinism and moral freedom. These ideas are contrasted against the largely Thesophical adaptation of the same concepts, which in the 19th and 20th centuries formed the emerging modern astrology in Europe, and which led it to aban
Robots interacting with other agents in rich information landscapes and complex dynamic physical environments require sophisticated and robust concept and knowledge management capabilities if they are to solve problems, communicate, learn and exhibit intelligent behaviours. In this paper we describe how conceptual spaces provide a powerful substrate upon which to build effective concept and knowle
To meet the demands of high electrical efficiencies in combination with low emissions for gas turbine-based power plants, wet cycles have gained new interest. The combustion chamber is a key component in such a power plant. Detailed investigations are necessary to gain insight into the formation of hazardous emissions such as CO and NOx. In this paper, computational fluid dynamics (CFD) has been e
In Statistical Shape Modeling, a dense correspondence between the shapes in the training set must be established. Traditionally this has been done by hand, a process that commonly requires a lot of work and is difficult, especially in 3D. In recent years there has been a lot of work on automatic construction of Shape Models. In recent papers (Davies et al., Medical Image Computing and Computer-Ass
Astrocytes play a critical role during the development and the maintenance of the CNS in health and disease. Yet, their lack of accessibility from fetuses and from the brain of diseased patients has hindered our understanding of their full implication in developmental and pathogenic processes. Human pluripotent stem cells (PSCs) are an alternative source to obtain large quantities of astrocytes in
Objective Intrauterine growth restriction (IUGR) is a recognized risk factor for neurological deficits later in life. Abnormal fetal blood flow in the presence of IUGR helps to distinguish fetuses with true growth impairment from those that are small but normally grown. This study aimed to evaluate the influence of IUGR with abnormal fetal blood flow on cognitive function and psychological develop
This article examines the modern concept of literary value. Since the late 18th century, the problem of literary value has been regarded, from the point of view of the so called double discourse of value, as a presupposed opposition between material and spiritual ”economies”. Many Romanticist and Modernist authors believe that literature – and in a broader sense art and aesthetics – constitute a v
The flexibility demands in manufacturing are severe, e.g., for rapid-change-over to new product variants, while robots are flexible machines that potentially can be adapted to a large variety of production tasks. Task definitions such as explicit robot programs are hardly reusable from an application point-of-view. To improve the situation, a knowledge-based approach exploiting distributed declara
The mechanism of atomic and molecular ionization in intense, ultra-short laser fields is a subject which continues to receive considerable attention. An inherent difficulty with techniques involving the tight focus of a laser beam is the continuous distribution of intensities contained within the focus, which can vary over several orders of magnitude. The present study adopts time of flight mass s
Trends towards distributed power generation and the deregulation of energy markets are increasing the requirement for software tools that optimize power generation plant design and operation. In this context, this paper describes the GTPOM (thermo-economic optimization of whole gas turbine plant) European project, funded in part through the European Commissions 5th Framework Programme, focusing on
