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Introduction: The use of pharmacokinetic assessment for optimal prophylactic dosing of factor concentrates in haemophilia has gained increasing enthusiasm over the last decade. However, blood sampling on several occasions is burdensome and limited sampling using population-based PK is appealing. Aim: To compare the pharmacokinetics and dosing recommendations for prophylaxis using six-point single
The term gastrointestinal neuromuscular disease describes a clinically heterogeneous group of disorders of children and adults in which symptoms are presumed or proven to arise as a result of neuromuscular, including interstitial cell of Cajal, dysfunction. Such disorders commonly have impaired motor activity, i.e. slowed or obstructed transit with radiological evidence of transient or persistent
In this work the synthesis of waterborne polyurethane/nanosilica nanocomposites by using two differ-ent strategies is presented, starting from a vinyl terminated polyurethane prepolymer (PUP) based onisophorone diisocyanate and polypropylene glycol, and varying the nanosilica content. In one case, thePUP was dispersed in an aqueous solution containing glycerol-functionalized colloidal nanosilica p
Background: Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their attitudes towards possible future mass screening. Methods: All adolescents (n =
Objective To determine coverage and generalisability of data in the Swedish Biologics Register ARTIS. Methods Patients with adult onset rheumatoid arthritis (RA) were identified in the National Patient Register and the Swedish Rheumatology Quality Register, including the ARTIS cohort of patients exposed to biological agents. Exposure to etanercept and adalimumab between 2006 and 2008 was determine
The aim was to investigate whole-body and red marrow absorbed doses in treatments of neuroblastoma (NB) and adult neuroendocrine tumors (NETs) with (131)I-metaiodobenzylguanidine and to propose a simple method for determining the activity to administer when dosimetric data for the individual patient are not available.
New basis sets of the atomic natural orbital (ANO) type have been developed for the lanthanide atoms La-Lu. The ANOs have been obtained from the average density matrix of the ground and lowest excited states of the atom, the positive ions, and the atom in an electric field. Scalar relativistic effects are included through the use of a Douglas-Kroll-Hess Hamiltonian. Multiconfigurational wave funct
The effects of a driver assistance system for keeping safe speed and safe distance (referred to as SASPENCE) on driver behaviour, reactions and acceptance were evaluated in a test carried out in 2006. Twenty test drivers, recruited by ads, drove two times (once with the system off and once with the system on) in real traffic conditions along a 50 km long test route containing urban and rural roads
Background and purpose Treatment of displaced femoral neck fractures in Sweden has shifted towards more arthroplasties, especially hemiarthroplasties. We describe the hemiarthroplasty population in Sweden 2005 through 2009. Methods Since 2005, the Swedish Hip Arthroplasty Register has registered hemiarthroplasties on a national basis. We assessed hemiarthroplasty procedures in the Register 2005-20
Radiochromic film, polymer gel and radiochromic plastic are three different kinds of dosimeters developed for radiation therapy and suitable for optical readout. In this study, different optical CT scanners are used to scan the dosimeters to find out if they could be used as multi-purpose scanners, i.e. for readout of the different kinds of dosimeters. Promising results are found but further devel
Mapping coastal inlets and their catchment areas is essential for management of the coastal zone. The coastal inlets are important channels of exchange of nutrients, water and sediment between the land and sea. They are also important elements of the coastal hydrological system and play a vital role in controlling the water flow into the sea during floods. Blocking of the coastal inlets is one of
Genome-wide association studies have recently identified at least 15 susceptibility loci for systemic lupus erythematosus (SLE). To confirm additional risk loci, we selected SNPs from 2,466 regions that showed nominal evidence of association to SLE (P < 0.05) in a genome-wide study and genotyped them in an independent sample of 1,963 cases and 4,329 controls. This replication effort identified fiv
In this study, the production of enantiomerically pure (1R,4S,6S)-6-hydroxy-bicyclo[2.2.2]octane-2-one ((-)-2) through stereoselective bioreduction was used as a model reaction for the comparison of engineered Saccharomyces cerevisiae and engineered Escherichia coli as biocatalysts. For both microorganisms, over-expression of the gene encoding the NADPH-dependent aldo-keto reductase YPR1 resulted
Händelser – Sida 4 – Biologibloggen Hoppa till huvudinnehåll Om Biologibloggen Tillgänglighet Kontakt Sök Sök Stäng Meny Biologibloggen Biologiska institutionen | Lunds universitet Arkiv för kategorin Händelser Sida 4 / 58 maj 21, 2025 | Inger Ekström Dagordning för styrelsemötet den 28/5 -25 Den 28 maj klockan 13.15 har institutionsstyrelsen möte i Stora Konferensrummet i Ekologihuset. Följande s
https://biologi.blogg.lu.se/category/handelser/page/4/ - 2026-06-26
Akustophores är rörelse av partiklar/celler under inverkan av ljud. Partikel- och cell separation är en applikation som kan utföras av akustophores. Detta är en viktig teknik eftersom den kan avslöja viktig information om sjukdomar och celler och därigenom förbättra valet av behandling inom sjukvården. Genom att utnyttja ljud, så kan celler och partiklar i en lösning separeras efter deras specifikAcoustophoresis is the migration of particles/cells under the influence of sound. Particle and cell separation is an application that can be performed by acoustophoresis. This is an important technique since it can reveal important information about diseases and cells and thereby possibly improve the choice of treatment in healthcare. By utilizing sound, cells and particles in a suspension can be
Encapsulation systems have long been studied, and the designs have varied in both capsule material as well as the type of cargo. The intended use have ranged from nanoreactors to delivery systems. This work presents an encapsulation system consisting of protein capsule and a protein cargo. The capsule is a redesigned hepatitis B virus capsid protein, in which the luminal extension has been altered
This research addresses the potential of political comedy and satire as television genres in the construction of democracy and civic culture in Colombia. Through a set of elite interviews with representative individuals in the media, political humor and media scholarship circles of the country; and through genre-based and political, economical and cultural analyses, this research underscores the r
Title (in English): Retail and Consumer Perceptions on Paper Packaging for Flour in Indonesia –with Insights on Perceptions of Environmental Sustainability Title (in Swedish): Handelns och konsumenternas uppfattningar om pappersförpackningar för mjöl i Indonesien - med insikter om hur de uppfattar miljömässig hållbarhet Author: Anindyaningrum Chrisant Rystiasih Divison: Packaging Logistics
Today there are still single family houses with direct electric heating systems, even though this is an expensive and inefficient way of heating a house. It is common to install an air-to-air heat pump that requires less electricity to produce the same amount of heat as a direct electricity heating system. These heat pumps do not produce any energy for domestic hot water since the water is heated
