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Aims/hypothesis: Coronary artery disease (CAD) is a common complication among individuals with diabetes. A better understanding of the genetic background of CAD in this population has the potential to suggest novel molecular targets for screening, risk assessment and drug development. Methods: We performed a genome-wide association study of CAD in 15,666 unrelated individuals (3,968 CAD cases and
The metabolism of individual polyunsaturated fatty acids (PUFA) may be influenced differently by nutritional status and nutritional intake. In normal rats, radioactive arachidonic acid (20:4(n-6), is preferentially retained in tissue phospholipids compared to linoleic (18:2(n-6), or eicosapentaenoic acid (20:5(n-3). This study compares the fate of 20:4(n-6) and 20:5(n-3) acids in essential fatty a
The laccase producing fungus HC1 was isolated from a sample collected in the Bolivian Amazon region. Analysis of 5.8S and 28S rDNA, and internal transcribed spacer 1 and 2 sequences revealed that isolate HC1 belongs to genus Galerina. High production of laccase was achieved in basal salt medium supplemented with 30 g L-1 glucose, 10 g L-1 yeast extract and 0.01 g L-1 co
Increasing atmospheric carbon dioxide concentration [CO2] caused by anthropogenic activities has triggered a requirement to predict the future impact of [CO2] on forests. The Hindu Kush Himalayan (HKH) region comprises a vast territory including forests, grasslands, farmlands and wetland ecosystems. In this study, the impacts of climate change and land-use change on forest carbon fluxes and vegeta
The properties of the amyloid-beta peptide that lead to aggregation associated with Alzheimer's disease are not fully understood. This study aims at identifying conformational differences among four variants of full-length Abeta42 that are known to display very different aggregation properties. By extensive all-atom Monte Carlo simulations, we find that a variety of beta-sheet structures with dist
High-frequency in situ measurements at Gosan (Jeju Island, Korea) during November 2007 to December 2008 have been combined with interspecies correlation analysis to estimate national emissions of halogenated compounds (HCs) in East Asia, including the chlorofluorocarbons (CFCs), halons, hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), sulfur hexafluoride (SF6),
Oxidative stress plays a crucial role in the development of several liver diseases. Many natural polyphenols can attenuate oxidative stress and liver injury. In this study, a phytochemical profiling of a methanol extract from leaves of Syzygium samarangense revealed 92 compounds belonging to flavonoids, phenolic acids, condensed tannins, and ellagitannins. The S. samarangense extract exhibited a n
BACKGROUND: Adenocarcinoma at the gastroesophageal junction may be regarded as of esophageal or of gastric origin, and tumor removal may follow the principles of esophagectomy or extended gastrectomy. We determined the impact of this strategy on our patients with tumors at this site. METHODS: Baseline patient and tumor characteristics were collected, and tumors were categorized according to Siewer
PURPOSE: Preoperative percutaneous transabdominal wall biopsy may be considered to diagnose gastrointestinal stromal tumour (GIST) and plan preoperative treatment with tyrosine kinase inhibitors when an endoscopic biopsy is not possible. Hypothetically, a transabdominal wall biopsy might lead to cell seeding and conversion of a local GIST to a disseminated one. We investigated the influence of pre
This is a study of seven men that have suffered from a cruel punishment. The punishment involved getting their ear/ears cut off, prison with more torture and their families being deported from their homes to another town. My sample involved seven Iraqi men who suffered from this punishment during Saddams regime, they got this punishment because they refused to fight against Iran and Kuwait. I wen
ABSTRACTBackground and Objective: Working from a harm reduction (HR) approach underscores that addictioncare professionals (ACPs) serve people with substance use disorder in a non-judgmental environment,encouraging people to seek intervention without abstinence as the ultimate goal. This study aims toexplore and compare the attitudes toward the acceptability of harm reduction among ACPs in SouthAf
Betaine-homocysteine S-methyltransferase (BHMT) is a zinc-dependent methyltransferase that uses betaine as the methyl donor for the remethylation of homocysteine to form methionine. This reaction supports S-adenosylmethionine biosynthesis, which is required for hundreds of methylation reactions in humans. Herein we report that BHMT is activated by potassium ions with an apparent KM for K+ of about
Rapport till UMAS ledning tisdag 14/11 2006 kl 13 TEDDY årsrapport 2011 1 2012-05-14 TEDDY studien (The Environmental Determinants of Diabetes in the Young) Årsrapport 2011 TEDDY årsrapport 2011 2 2012-05-14 Innehållsförteckning Bakgrund………………………………………………………… 3 Typ 1 diabetes är en sjukdom i två steg……………………. 3 Varför får barn autoantikroppar mot sina beta-celler?...... 4 Varför får barn med autoa
https://www.teddy.lu.se/sites/teddy.lu.se/files/2011_teddy_arsrapport.pdf - 2026-07-18
GoLab får 19 miljoner av Riksbankens Jubileumsfond GoLab får 19 miljoner av Riksbankens Jubileumsfond Publicerad den 1 december 2025 Nu blir det möjligt att ta labbet till studieobjekten – och inte tvärtom. Humanistlaboratoriets GoLab kan nu förvärva mobil teknokologi som gör det möjligt för forskare att studera kognition, kommunikation och kultur i verkliga livet – som barn i klassrum, äldre i he
https://www.ht.lu.se/article/humanistlaboratoriets-golab-faar-19-miljoner-av-riksbankens-jubileumsfond/ - 2026-07-16
