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Affymetrix GeneChip technology and quantitative real-time PCR (Q-PCR) were used to examine changes in gene expression in the adult murine substantia nigra pars compacta (SNc) following lentiviral glial cell line-derived neurotrophic factor (GDNF) delivery in adult striatum. We identified several genes that were upregulated after GDNF treatment. Among these, the gene encoding the transmembrane prot
Antibiotic resistance is currently an extensive medical challenge worldwide, with global numbers increasing steadily. Recent data have highlighted wastewater treatment plants as a reservoir of resistance genes. The impact of these findings for human health can best be summarized using a One Health concept. However, the molecular mechanisms impacting resistance spread have not been carefully evalua
Human telomerase reverse transcriptase (hTERT) is a critical factor in unlimited cell proliferation and immortalization, with numerous studies demonstrating that high expression of hTERT is a poor prognostic factor in various types of cancer. Ubiquitin-conjugating enzyme E2D 3 (UBE2D3) is a member of the E2 family, and participates in the ubiquitin proteasome pathway to regulate basic cellular act
BACKGROUND: Survivin regulates cell division and inhibits apoptosis. Liver regeneration is a complex process involving both proliferation and apoptosis. The role of survivin is not well elucidated and no data exist in humans.METHODS: Seventy per cent liver resection was used to investigate liver regeneration in rats. Survivin was identified by means of reverse transcriptase polymerase chain reacti
Huminfra är en svensk nationell infrastruktur som stödjer digital och experimentell forskning inom humaniora. Huminfra leds av Humanistlaboratoriet vid Lunds universitet och omfattar 12 noder fördelade på 11 lärosäten och organisationer. Huminfra finansieras av Vetenskapsrådet och av noderna i konsortiet. Den webbaserade informationsplattformen huminfra.se sammanställer och länkar till svenska dHuminfra is a Swedish national infrastructure supporting digital and experimental research in the Humanities. Huminfra is a consortium consisting of 12 nodes across 11 universities and organisations, coordinated by Lund University Humanities Lab. Huminfra is funded by the Swedish Research Council, and the consortium nodes. The web-based information platform huminfra.se compiles and links to Swedi
Kvinnor med svår knäskada mår sämre än män – Vetenskap och Hälsa Hoppa till innehåll Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kvinnor med svår knäskada mår sämre än män 2010-05-21 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Kvinnor som drabbas av en allvarlig knäskada
https://www.vetenskaphalsa.se/kvinnor-med-svar-knaskada-mar-samre-an-man/ - 2026-07-17
IL-8 is a major human neutrophil chemoattractant at mucosal infection sites. This study examined the C-X-C chemokine response to mucosal infection, and, specifically, the role of macrophage inflammatory protein (MIP)-2, one of the mouse IL-8 equivalents, for neutrophil-epithelial interactions. Following intravesical Escherichia coli infection, several C-X-C chemokines were secreted into the urine,
ClpP is the proteolytic subunit of the ATP-dependent Clp protease in eubacteria, mammals and plant chloroplasts. Cyanobacterial ClpP protein is encoded by a multigene family, producing up to four distinct isozymes. We have examined the importance of the first ClpP protein (ClpP1) isolated from the cyanobacterium Synechococcus sp. PCC 7942 for acclimation to ecologically relevant UV-B and low-tempe
C4b-binding protein (C4BP) regulates the classical pathway C3-convertase of the complement system. Human C4BP is composed of seven identical subunits (alpha-chains) and one unique one (beta-chain). Both types of chains contain homologous repeats called complement control proteins (CCPs); the alpha-chain contains eight CCPs and the beta-chain three. Each alpha-chain contains a binding site for C4b
In recent years the concept of “Blue carbon” has brought attention to the importance of Mangroves, Seagrass and Saltmarsh ecosystems in carbon cycles. Concerns over climate change has had countries commit to decreasing CO2 emissions, often using natural processes to sequester CO2. This trend has often followed a market approach through creating a monetary value and market for CO2. This Climate Fin
BackgroundDespite the fact that eldercare services are organizationally part of social work in Sweden, the social work practice is disappearing and older people are expected to take the responsibility for their own well-being. In this context, they have to create their own sense of meaningfulness in their everyday life, despite being subject to social care services.Methods As part of a research pr
