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There have been several water main breaks attributed to fire hydrant operations despite the persistent guidance from stakeholders to operate the hydrants “slowly.” Traditional water hammer simulations for determining the safe operational times for every hydrant can be tedious and impractical for most water utilities. While the rapid operation of certain hydrants can generate excessive pressures, m

Renal dysfunction is a major risk factor for premature death and has been studied extensively. A new renal syndrome, shrunken pore syndrome (SPS), confers higher mortality in all studied populations. SPS is a condition in which cystatin C-based estimation of glomerular filtration rate (eGFRcystatin C) is ≥ 60% than creatinine-based estimation of glomerular filtration rate (eGFRcreatinine). We aime

Although endometriosis is considered an inflammatory disease, no reliable diagnostic biomarkers exist for use in clinical practice. The aim was to investigate the inflammatory profile in endometriosis using an exploratory approach of inflammation-related proteins. Patients with laparoscopy-verified endometriosis (N = 172), women with microscopic colitis (N = 50), healthy controls (N = 31), and age

Despite global modern economic growth, most countries remained stuck in persistent poverty. Jeffrey Sachs suggested considering poverty itself as the explanation for persistent levels of poverty and low growth. The theory is based on the existence of poverty traps, which keep families and countries caught in poverty. This research contributes to the poverty trap literature by evaluating the effect

Talent Management is a vague concept that is covering everything from recruiting, developing and retaining talents within organisations. A constant challenge in this field is to develop new generations within the workforce to fit what the organisation needs in order to do business. Generations are said to be shaped after historical and political factors that are impacting their behaviors and requi

Background: In a previous smaller study, we found evidence of a diminished global coagulation capacity after maximal exercise in patients with severe haemophilia A (HA). Aim: To validate these results, we repeated the study in a larger cohort. We also examined if the exercise-induced increased levels of von Willebrand factor (VWF) might prolong the effect of factor concentrate administered just be

Attribution has become a recurring issue in discussions about Loss and Damage (L&D). In this highly-politicised context, attribution is often associated with responsibility and blame; and linked to debates about liability and compensation. The aim of attribution science, however, is not to establish responsibility, but to further scientific understanding of causal links between elements of the

The authors analyzed the relationship between treatment, local recurrence, and metastases in a population‐based series of 375 patients with soft tissue sarcoma of the extremities and the trunk wall. Treatment was inadequate (marginal excision alone) in 107 patients, local recurrence occurred in 112, and 128 patients developed metastases. Local recurrence was 3.5 times more common after inadequate

The LIN28B RNA binding protein exhibits an ontogenically restricted expression pattern and is a key molecular regulator of fetal and neonatal B lymphopoiesis. It enhances the positive selection of CD5+ immature B cells early in life through amplifying the CD19/PI3K/c-MYC pathway and is sufficient to reinitiate self-reactive B-1a cell output when ectopically expressed in the adult. In this study, i

Mitochondria play essential roles in plant metabolism, supporting both development and stress responses. To maintain a healthy pool of mitochondria, several quality control systems are in place. Selected degradation of mitochondria by autophagy -mitophagy- has been extensively studied in yeast and animals, but information on mitophagy components in plants is limited. The ‘Friendly Mitochondria’ (F

Background: Perioperative fluid overload has been reported to increase complications after a variety of operative procedures. This study was conducted to investigate the incidence of fluid retention after pancreatic resection and its association with postoperative complications. Methods: Data from 1174 patients undergoing pancreatoduodenectomy between 2010 and 2016 were collected from the Swedish

Horizontal gene transfer by conjugative plasmids plays a critical role in the evolution of antibiotic resistance. Interactions between bacteria and other organisms can affect the persistence and spread of conjugative plasmids. Here we show that protozoan predation increased the persistence and spread of the antibiotic resistance plasmid RP4 in populations of the opportunist bacterial pathogen Serr

Background: The pathogenesis of COPD is complex and remains poorly understood. The European Respiratory Society Study on Chronic Obstructive Pulmonary Disease (EUROSCOP) investigated long-term effects of budesonide; 18% of the COPD participants were atopic. So far effects of atopy on the long-term course of COPD have not been elucidated. Methods: Factors related to the presence of atopy (positive

Studiens fokus är på skogsbränderna i Sverige år 2018, då tio gånger mer markyta påverkades av bränder än genomsnittet under föregående år. Syftet med studien är att undersöka en bred forskningsfråga: har vägar en påverkan på storleken hos den brända ytan i en löpeld? Studien bygger på tidigare forskning om hur spridningen av löpeld påverkas av vägar. Bland olika statistiska metoder valdes slutligThis study focuses on the Swedish wildfire season of 2018, when the country incurred ten times more than the average burnt area that occurred in previous years. The study aims to address a broad research question: Do roads influence the size of the burned area? This study fills the gap in research on the effects of roads in the spatial patterns of wildfires. Moreover, the research hopes to include