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Reindeer husbandry has long been a central element of the traditional livelihood and culture of indigenous Sami people in northern Sweden. However, it faces several challenges from competing land uses, primarily forestry. Different forest conditions are desired by forestry and reindeer husbandry to accommodate each sectors’ distinct interests, promoting high timber and pulp production or improved
The global pandemic of Covid-19 has drastically changed the behaviour of citizens around the world. This research aims to identify actions that ensure low-carbon, inclusive forms of mobility that respond to the behavioural changes during Covid-19. The city of Hamburg, Germany, and its problems with transport-related emissions and socio-economic inequalities serve as a representative case study. Th
Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improvi
The thesis explores the interaction between patent rights for Standard Essential Patents(SEP) and competition law, particularly Article 102 of the Treaty on the Functioning of the European Union(TFEU), within the context of the European Union(EU) , and compares this interaction with the relevant provisions in the proposed EU SEP regulation COM(2023)232. Three research questions will be discussed:
This thesis addresses the complexities of the situation of the Roma in Romania and Spain and the challenges of including isolated groups in society. The main texts used for comparison come from the Council of Europe’s expert bodies: the European Commission Against Racism and Intolerance (ECRI), the Advisory Committee (ACFC) under the Framework Convention for the Protection of National Minorities (
The essential spectrum of the singular matrix differential operator of mixed order determined by the operator matrix [GRAPHICS] is studied. Investigation of the essential spectrum of the corresponding self-adjoint operator is continued but; now without assuming that the quasi-regularity conditions are satisfied. New conditions that guarantee that the operator is semi-bounded from below are derived
Hereditary defects of the von Willebrand factor (VWF) gene cause von Willebrand's disease (VWD) which shows great variability dependent on the nature and location of the mutation. We here describe the characteristics of a substitution of methionine for threonine 1156 in the D3 domain of the VWF, i.e. the domain involved in the intracellular multimerization of pro-VWF dimers. A VWD patient withseve
The early B cell factor (EBF) is a transcription factor shown crucial for the development of B lymphocytes. The protein is expressed from the earliest stages of B cell development until the mature B cell stage, but the control elements responsible for the regulation of the gene are unknown. In this study, we report of the identification of a promoter region flanking the EBF gene. Several transcrip
Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
This paper reports on a search for narrow resonances in diboson production in the [Formula: see text] final state using [Formula: see text] collision data corresponding to an integrated luminosity of [Formula: see text] fb[Formula: see text] collected at [Formula: see text] TeV with the ATLAS detector at the Large Hadron Collider. No significant excess of data events over the Standard Model expect
Stem cells are unspecialized cells able to divide and produce copies of themselves and having the potential to differentiate, i.e. to produce other cell types in the body. Because of the latter ability, the scientists investigate their possible use in regenerative medicine. Especially embryonic stem cells have huge therapeutic potential because they can give rise to every cell type in the body as
The cystatin C gene (CST3) encodes a low-molecular-weight cysteine proteinase inhibitor belonging to family II of the cystatin super family and is mutated in cases of hereditary cystatin C amyloid angiopathy (HCCAA). CST3, which along with other family II cystatin genes is a member of the cystatin gene family, has been assigned to chromosome 20. To investigate the genomic organization on chromosom
Background: The national programs for the harmonization of hemoglobin (Hb)A(1c) measurements in the US [National Glycohemoglobin Standardization Program (NGSP)], Japan [Japanese Diabetes Society (JDS)/Japanese Society of Clinical Chemistry (JSCC)], and Sweden are based on different designated comparison methods (DCMs). The future basis for international standardization will be the reference system
The Archean basement in the northeastern part of the Kaapvaal craton is intruded by a large number of mafic dykes, defining three major dyke swarms, which collectively appear to fan out from the Bushveld Complex. Herein we present U-Pb baddeleyite ages for two of these dyke swarms, the northwest trending Badplaas Dyke Swarm and the east-west trending Rykoppies Dyke Swarm, and infer their correlati
Palaeomagnetic and geochronological studies on mafic rocks in the Lake Ladoga region in South Russian Karelia provide a new, reliably dated Mesoproterozoic key paleopole for the East European Craton (Baltica). U-Pb dating on baddeleyite gives a crystallisation age of 1452 +/- 12 Ma for one of the studied dolerite dykes. A mean palaeomagnetic pole for the Mesoproterozoic dolerite dykes. Valaam sill
A search has been made for supersymmetry in a final state containing two photons and missing transverse momentum using the ATLAS detector at the Large Hadron Collider. The search makes use of 3.2fb-1 of proton-proton collision data collected at a centre-of-mass energy of 13 TeV in 2015. Using a combination of data-driven and Monte-Carlo-based approaches, the Standard Model background is estimated
Objective: In a randomized clinical trial (COU-AA-301), abiraterone acetate (Zytiga®) was shown to be superior to prednisone in the treatment of metastatic castration-resistant prostate cancer (mCRPC). However, the value of abiraterone treatment for patients with mCRPC in clinical practice in Sweden is not known. The aim of this study was to compare the outcomes and treatment patterns of abiratero
Annually laminated sediments of Lake Woserin in north-eastern Germany are investigated using sedimentological and palynological methods. They facilitate high-resolution reconstruction of environmental and land-use change during ca. 7000–4000 cal. BP. Between 6100 and 5800 cal. BP, changes in woodland composition and structure are evident which coincide with a change in subsistence strategy, that i
