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Despite its importance, rural groundwater quality in Rwanda remains insufficiently monitored. This study aimed to investigate the groundwater quality, its health implications as well as how management can be improved to reduce the health risks of rural boreholes in the Nyagatare district in Rwanda. In total 61 boreholes were visited and 48 groundwater samples were collected. Analysis was conducted
This thesis examines how outnovation is enacted within design entrepreneurship, with fashion design entrepreneurship as the empirical context. It analyses how value formed through design practice may contribute to sustainable competitive advantage. Understood as an alternative innovation logic centred on authenticity, nostalgia, simplicity, and sustainability, outnovation offers a counterpoint to
Immunotherapy aims to enhance the immune system’s response to cancer. Different immunotherapies exist, such as cytokine therapies and immune checkpoint inhibitors. The FDA has approved immunomodulatory drugs, such as Proleukin, a recombinant IL-2 cytokine, Nivolumab, and Avelumab, which are immune checkpoint inhibitors. However, these drugs lead to side effects in patients known as immune-related
The ECJ’s judgment of 27 January 2021 in the case C-595/18 P (the ”Goldman Sachs case”) has caused a big buzz in the ever growing Private Equity sector. It confirmed the ruling of the GCEU of July 2018 case T-419/14 which in turn confirmed the Commission’s decision according to which Goldman Sachs has been held liable for an antitrust infringement committed by one of its portfolio companies. In al
The issue of corporate accountability for human rights has gained significant attention in recent years, driven by increasing globalisation, complex corporate structures, and the public’s growing awareness of the harmful effects of business activities. Alongside the rising prominence of human rights on the international agenda, the issue of environmental impacts of corporations has also become mor
Cash holding strategy is an important financial decision for firms. It is highly related to firms’ operation and development because cash is an important guarantee to meet the business payment and investment opportunity. However, some scholars believe that due to agency problems, too much cash holdings are likely to produce negative impact on enterprise value. Compared to listed firms on Chinese A
People’s ability to learn holds a promise for sustainability as learning is seen to enable change; yet, the prevalence of norms and values in society that reinforce unsustainability may severely challenge this process. The debate on what role learning can play is centered around the question whether people can learn from others and if so, how to enhance it. More precisely, who has to learn what fr
This thesis poses structural and behavioural competition problems in digital markets in terms of core platforms services provided by the gatekeepers under the proposed Digital Markets Act by the European Commission, where such problems are the most evident. This thesis analyses whether existing competition and more sector-specific legal tools are functional to address these problems. Traditional l
Examining the relation between Swedish households’ debt, property price and interest rates are important when forming monetary policy implications. Several studies have examined the driving factors of household debt and property price, however the results are inconclusive. This thesis differs from previous research as it includes the variable interest to income ratio, instead of debt ratio, as the
Bumblebees and other pollinators are important contributors to the ecosystem service of pollination of wild plants and crops. As in many pollinating insects, their abundance and diversity have declined in recent years, due to loss of natural habitats and fragmentation associated with urbanization and agricultural intensification. However, in urban areas, green space management beneficial to pollin
The present thesis explores the requirement of the waiting period to grant family reunification to Third Country Nationals from the perspective of human rights law. It examines how this requirement, which currently forms a significant part of immigration policies within European member states, may impact TCNs' Right to family life under the European Convention on Human Rights (ECHR) and EU
Access to water is taken for granted in water abundant countries like Sweden, but safe water supply is increasingly threatened by droughts. This thesis analyses how the Swedish water sector responded to the unprecedented drought in 2018, by analysing water security discourse through the framework “What’s the problem represented to be?”. It explores implications of the drought on water policy and h
The recent advent of 3DSG in the computer vision domain has brought powerful high-level representations of 3D environments. These representations strive to mimic human perception and facilitate the extraction of meaningful insight from visual data. This research has led to framework like Hydra, which creates a real-time, persistent spatial perception system that creates a complete 3D map of their
The objective of this report is twofold: to optimise the extraction method of lignin from spruce altering a few process parameters and to investigate the use of lignin as a hydrophobic barrier in food applications. The process used was STEX (steam explosion) pretreatment followed by enzymatic hydrolysis and MWL (milled wood lignin) extraction using a mixture of dioxane-water. The lignin was then c
The planetary system around the naked-eye star v2 Lupi (HD 136352; TOI-2011) is composed of three exoplanets with masses of 4.7, 11.2, and 8.6 Earth masses (M⊕). The TESS and CHEOPS missions revealed that all three planets are transiting and have radii straddling the radius gap separating volatile-rich and volatile-poor super-earths. Only a partial transit of planet d had been covered so we re-obs
Cell replacement therapies for Parkinson's disease (PD) based on transplantation of pluripotent stem cell-derived dopaminergic neurons are now entering clinical trials. Here, we present quality, safety, and efficacy data supporting the first-in-human STEM-PD phase I/IIa clinical trial along with the trial design. The STEM-PD product was manufactured under GMP and quality tested in vitro and in viv
Life on Earth was sharply disrupted 66 Ma ago as an asteroid hit the sea-floor in what is today Yucatan Peninsula, Mexico. Approximately 600 km(3) of sedimentary rock were vapourized, ejected into the atmosphere and subsequently deposited globally as an ejecta apron and fallout layer. Proximal ejecta deposits occur in Belize and southern Mexico where the so called Albion island spheroid bed is sup
Background: Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro- and nanodosimetry, imaging, radiation protection, and nuclear medicine. Geant4 is continuously evolving, so it is crucial to have a system that benchmarks this Monte Carlo code for medical physics against reference data and to perform regression testing. Aims: To
Although animals are born with a protective immune system, even the innate immune system is under development from birth to adulthood and this development may be affected by sex and growth. However, most knowledge comes from captive animals or long-lived slow growing species. Moreover, little is known about how innate immune function, the important first line of defence, develops during early life
