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Introduction: The aim of this study was to estimate the incidence of recurrent pregnancy loss (RPL). The prevalence of RPL defined as three or more consecutive miscarriages before gestation week 22, is often stated to be 1%. To our knowledge no study has estimated the incidence of RPL, which might be more informative and clinically relevant than the prevalence. Material and methods: This retrospec
Objective. To assess lung cancer risk in systemic lupus erythematosus (SLE), relative to demographics, drug exposures, smoking, and disease activity. Methods.We analyzed data from 14 SLE cohorts. We calculated adjusted HR estimates for lung cancer in SLE, relative to demographics, smoking, time-dependent medication exposures, and cumulative disease activity [mean adjusted SLE Disease Activity Inde
Huntington's disease (HD) is a devastating, inherited neurodegenerative disorder caused by an expanded CAG repeat in the huntingtin gene. Peripheral symptoms, such as skeletal muscle wasting, progressive weight loss, altered body composition and endocrine disturbances exist alongside neurodegeneration. Both the mutant gene and protein are expressed in cells and tissues throughout the body.Weight l
Climate warming raises the question whether high-latitude landscape still function as net carbon (C) sinks. By compiling an integrated C balance for an intensely studied subarctic catchment, we show that this catchment's C balance is not likely to be a strong current sink of C, a commonly held assumption. In fact, it is more plausible (71% probability) that the studied catchment functions as a C s
Julian D. Mortenson has written an article for the most recent issue of the American Journal of International Law which he has furnished with the title "The Travaux of Travaux: Is the Vienna Convention Hostile to Drafting History?" The article suggests a reading of Articles 31 and 32 of the 1969 Vienna Convention on the Law of Treaties that is radically different from the one generally assumed. As
In this paper, I evaluate some recent attacks on Williamson's claim that knowledge is the most general factive stative propositional attitude. Two types of approaches are discussed: The first approach attempts to show that there are factive mental states denoted by factive mental state operators that are not cases of knowing. The second approach aims to show that there are factive mental states th
Thermodynamics connects our knowledge of the world to our capability to manipulate and thus to control it. This crucial role of control is exemplified by the third law of thermodynamics, Nernst's unattainability principle, which states that infinite resources are required to cool a system to absolute zero temperature. But what are these resources and how should they be utilized And how does this r
In Arabidopsis thaliana, winter is registered during vernalization through the temperature-dependent repression and epigenetic silencing of floral repressor FLOWERING LOCUS C (FLC). Natural Arabidopsis accessions show considerable variation in vernalization. However, which aspect of the FLC repression mechanism is most important for adaptation to different environments is unclear. By analysing FLC
Is a suction cup at the bottom of a bathtub subject to an upward force from the surrounding water, even if there is no water under it? A student question, posted in a teacher facebook group on a Monday morning, led to a discussion involving 21 comments with 225 replies offered by 16 teachers during the next few days, including several simple experiments, as well as modeling, to evaluate different
Background: The diagnostic accuracy of colon capsule endoscopy (CCE) depends on a well-cleansed bowel. Evaluating the cleansing quality can be difficult with a substantial interobserver variation. Objectives: Our primary aim was to establish a standard of agreement for bowel cleansing in CCE based on evaluations by expert readers. Then, we aimed to investigate the interobserver agreement on bowel
Laboratoriet för metabola störningar och leversjukdomar leds av Philipp Kaldis, som är professor vid Institutionen för kliniska vetenskaper och vice koordinator för Lunds universitets Diabetescentrum (LUDC). Nya data tyder på att upp till 30% av befolkningen lider av leversjukdomar inklusive icke-alkoholorsakad fettleversjukdom (NAFLD), som kan vidareutvecklas till icke-alkoholorsakad steatohepatiThe metabolic disorders and liver disease laboratory is headed by Philipp Kaldis, who is a Professor in the Department of Clinical Sciences and a vice-coordinator of the Lund University Diabetes Centre (LUDC). Recent data suggests that up to 30% of the population suffers from liver diseases including non-alcoholic fatty liver disease (NAFLD), which can further develop to non-alcoholic steatohepati
1. We measured the abundance and biomass of filter-feeding microcrustacean zooplankton and calculated their grazing impact on phytoplankton biomass during summer in five shallow, mesotrophic to eutrophic lakes. For three of the lakes data exist both from years with dense submerged vegetation and low turbidity (the clearwater state), as well as from years characterised by sparse vegetation and high
Digitaliseringen har ändrat samhället på många sätt. Idag delar människor med sig av all sorts information om sig själva och andra under nästan alla timmar på dygnet. Människor har anpassat sig till ett samhälle där de känner sig manade att hela tiden vara uppkopplade och representerade på internet. På senare tid har dock människor börjat inse att spridandet av information på internet kan ge oanadDigitalization has changed society in many ways. One of the results of the development of the online world is that people have formed the habit of sharing all sorts of information about themselves and others to everyone around them at all times. People have adapted to a society where they feel a compulsion to be repeatedly connected and represented on digital networks. However, individuals have st
The aim was to explore health in relation to the home as experienced by very old, single-living Swedish people. Applying a grounded theory approach, 40 men and women aged 80-89 were interviewed in their own homes. Data analysis revealed the main theme, "The home is the hub of health", comprising two categories, "The home as support for health", and "Having an inner driving force to maintain health
As capitalist society remains incapable of addressing climate breakdown, one measure is waiting in the wings: solar geoengineering. No other technology can cut global temperatures immediately. It would alleviate the symptoms of the crisis, not its causes. But might it be combined with radical emissions cuts? This essay, the first instalment of two, scrutinises the rationalist-optimist case for geo
