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The cytokine TGFβ1 induces epidermal Langerhans cell (LC) differentiation from human precursors, an effect mediated through BMPR1a/ALK3 signaling, as revealed from ectopic expression and receptor inhibition studies. Whether TGFβ1‒BMPR1a signaling is required for LC differentiation in vivo remained incompletely understood. We found that TGFβ1-deficient mice show defective perinatal expansion and di
Rural destinations like Kullahalvön are becoming more and more popular as tourists look for authentic local experiences. However, the synergy between stakeholder engagement and rural branding has not received much attention in studies. We explore the complexities of destination branding and stakeholder collaboration in Kullahalvön in this qualitative study. By means of a comprehensive document ana
A major interest in the gall-inducing thrips of Australia began with the discovery that some species have eusocial colonies. The origin of social castes remains one of the outstanding questions in evolutionary biology. The inference of the ancestral stage from study of solitary species is important to understanding the evolutionary history of semiochemicals in social species. Here we investigated
Cyclic nucleotide phosphodiesterases (PDEs) are important regulators of signal transduction processes mediated by cAMP and cGMP. One PDE family member, PDE3B, plays an important role in the regulation of a variety of metabolic processes such as lipolysis and insulin secretion. In this study, the cellular localization and the role of PDE3B in the regulation of triglyceride, cholesterol and glucose
Gruppen driver forskning kring mätning och behandling av svår kronisk andnöd (dyspné) samt behandling av kronisk andningssvikt. Gruppen har nära samarbete med ledande forskare nationellt och ett internationellt forskningsnätverk kring klinisk dyspnéforskning. Studier inkluderar epidemiologiska analyser, Cochrane meta-analyser, kliniska kohortstudier samt randomiserade kontrollerade behandlingsstudThe research group focuses on the mechanisms, measurement and treatment of severe chronic breathlessness (dyspnea) and management of chronic respiratory failure. The research is conducted in close collaboration with leading researchers nationally and an international research network. Studies include epidemiological analyses, Cochrane meta-analyses, clinical cohorts and randomized controlled trial
Enheten för psykiatrisk epidemiologi och folkhälsa studerar ämnesområden som exempelvis psykossjukdomar, suicidologi, beroendetillstånd och neuropsykiatriska tillstånd med klassiska och moderna epidemiologiska metoder. Dessa frågor belyses dels utifrån ett kliniskt perspektiv med traditionella frågeställningar gällande riskfaktorer, utfall, överlevnad och farmakoepidemiologi, dels utifrån ett folkThe Unit for Psychiatric Epidemiology and Public Health studies subject areas such as psychotic disorders, suicidology, substance use disorders, and neuropsychiatric conditions using classical and modern epidemiological methods. These issues are examined both from a clinical perspective, with traditional research questions regarding risk factors, outcomes, survival, and pharmacoepidemiology, and f
Martin Sunnqvist, Eva Lindell- Frantz, Eduardo Gill-Pedro, Linnea Wegerstad, Vladislava Stoyanova, Yana Litins'ka, Suppleanter: Marja Liisa Öberg, Per Nilsen, Marcus Utterström
Enheten för forskningsdata (Research Data Office, RDO) stöttar forskare vid Lunds universitet i hela forskningsprocessen genom att ge vägledning till rätt stöd,verktyg och tjänster för hantering av forskningsdata. Enheten har en samordnande roll och ska verka för att stärka kvaliteten och genomslaget i forskningen, exempelvis genom att stötta forskare att göra data mer tillgänglig, säker och hållbLund University Research Data Office (LU RDO) supports researchers at Lund University throughout the research process by providing guidance on the right support, tools and services for managing research data. The office has a coordinating role and will work to strengthen the quality and impact of research, for example by supporting researchers to make data more accessible, secure and sustainable,
Soils play a critical role in the carbon (C) cycle by regulating the atmospheric carbon dioxide (CO2) levels, and correspondingly the Earth’s climate. However, there are still countless questions of how biological and geochemical soil processes affect the C cycle. To be able to predict future implications on the Earth’s climate, we need to understand these processes. Globally, soils store more C tIron oxide nanoparticles are involved in several important biogeochemical processes. The interfaces between aqueous solutions and iron oxide nanoparticle surfaces are found everywhere in nature, and the chemical and microbial processes occurring at these complex interfaces control e.g. nutrient and contaminant availability and transport. Recently, it has been shown that certain ectomycorrhizal (EC
The exclusive economic right of communication to the public granted to authors in respect of their works, as enshrined in Article 3(1) of the Information Society Directive 2001/29/EC, has been the focal point of extensive litigation, surpassing any other provision within European Union (EU) copyright legislation. Undertaking legal dogmatic research, this thesis seeks to delineate the scope of Arti
This thesis investigates how the cinematographic techniques implemented during eating and sex scenes in movies involving queer characters affect the feelings of the spectator. In more detail, it proposes to elaborate on the emphasis placed on carnal pleasure and the corporeal sensation of queer characters with a specific focus on the corporeal reaction provoked in the viewer. The elaboration is bu
This article explores the advocacy activities of the Church of Sweden. The historical co-optation of the Church by the state, a Lutheran theological heritage, and a trend from “voice to service” within Swedish civil society might discourage stronger political activism by the Church. The following research questions are answered: How does the extent of the advocacy activities of the Church of Swede
Popular Abstract in Swedish Strålbehandling har sedan länge visat sig vara en bra metod för att behandla patienter med cancer. Den nya teknik som har introducerats under de senaste åren har möjliggjort ökade stråldoser till än mer begränsade volymer. Samtidigt innebär detta att ökade krav ställs på att man försäkrar sig om att den volym man bestrålar är den volym som innehåller tumörceller och attMethods for ensuring that the intended volume receives the intended absorbed dose in radiotherapy have been investigated. In order to optimise radiation treatment of cancer, geometric variations in the treatment chain need to be controlled. Furthermore, hazards potentially leading to unintended irradiation need to be controlled. While the required methods for optimisation of irradiation are divers
Forskargruppen bedriver forskning kring förutsättningar och rehabilitering för ett hälsosamt liv där rörelse och aktivitet är i fokus. Forskning som bedrivs i gruppen syftar också till att förbättra förståelsen för påverkan på människans strukturer, funktioner, aktiviteter och delaktighet i omgivande Iiv. Forskagruppens arbete omfattar hela kedjan från hälsopromotion till rehabilitering, genom heResearch within the group concerns conditions and rehabilitation for a healthy life, with a focus on movement and activity. Research within the group also aims to improve understanding of effects on human structure, functions, activities, and participation in society. Research within the group includes the line from health promotion to rehabilitation, throughout the lifespan. Other areas are work-
Med vår forskning vill vi förstå och främja människors psykiska hälsa, aktivitet och delaktighet och bidra till att människor kan leva ett så meningsfullt liv som möjligt och delta i samhället trots psykisk ohälsa. Att utveckla, utvärdera och implementera återhämtningsinriktade insatser som ger stöd i olika livssituationer och miljöer är därför centralt. Vi vänder oss till olika målgrupper såsomWith our research, we want to understand and promote persons’ mental health, activity and participation and as a result help them to live as meaningful lives as possible and participate in society despite mental ill health. Developing, evaluating and implementing recovery-oriented interventions that help in different life situations and in different environments is therefore critical. We address
