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Bacterial extracellular vesicles (EVs) are shed during growth by the respiratory pathogens Pseudomonas aeruginosa and Haemophilus influenzae. Vesicles trigger release of antimicrobial compounds and proteins of the complement, which are partly regulated by vitronectin. We hypothesized that vitronectin is elevated in the lungs during pneumonia, that respiratory epithelial cells produce vitronectin u
Background: Previous studies have reported an increased fracture risk after bariatric surgery. Objective: To investigate the association between different bariatric surgery procedures and fracture risk. Methods: Incidence rates and hazard ratios for fracture events were analysed in the Swedish Obese Subjects study; an ongoing, nonrandomized, prospective, controlled intervention study. Hazard ratio
Our mission is to establish a major trans-faculty bio-imaging center at Lund University (Lund University Bioimaging Center), combining knowledge in the fields of medical physics, preclinical and clinical medicine, chemistry, technology and applied mathematics in order to develop imaging methods for the advanced study of human morphology, cellular metabolism and physiological function in health and
Why the performance of local value-adding firms supplying to mining MNCs in Zambia’s liberalized economy seems more constrained was the investigated problem. I conducted a multiple case study research involving 15 firms located on Copperbelt Province. Local value-adding firms are cardinal to national industrial development through their backward linkage role to mines. However, their performance is
#090. Noise is interrupting my practice: Silence is when my reaction is quiet. Silence is my protest against the way things are, for piano and amplification (2014)
Epilepsy is a devastating neurological disorder characterized by synchronous neuronal activity, which manifests as epileptic seizures. It usually develops after an initial insult, such as head trauma or stroke, which triggers the epileptogenic process. During epileptogenesis, the affected brain regions undergo multiple changes in connectivity and gene expression, and among the most affected genes
This thesis explores how the heterotopic and liminal dimensions of Munich’s Oktoberfest produced differentiated visitor experiences, and how spatial, temporal, ritual, and social dynamics mediate feelings of authenticity, communitas, and belonging across visitor types. Adopting an interpretivist, social constructionist approach, the thesis combines semi-structured interviews with 15 participants a
Objective: Investigate the role of metabolic syndrome and obesity in incident osteoarthritis (OA). Methods: Prospective cohort study with up to 11 years follow-up. From a general population cohort of 28,786 individuals from Sweden aged 45 to 75, we selected individuals without OA diagnosis and without joint pain during the year prior to the baseline. Metabolic syndrome was defined at baseline by t
The present thesis aims to assess the efficacy of the GDPR in managing personal data breaches in healthcare. To fulfil its purpose, we have analysed the legal basis for processing sensitive personal health data and we have set the following research question: To what extent does the GDPR prevent personal health data breaches as well as mitigate their impact on data subjects? In order to conduct
Epidemiological studies reveal growing evidence that most cases of Alzheimer`s Disease (AD) likely involve a combination of genetic and environmental risk factors. Identifying and validating these risk factors remains one of the most critical scientific challenges. Several diseases appear to have strong implications for neurodegeneration leading to dementia. This risk encompasses different forms o
