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Previously, a single nucleotide polymorphism (SNP), rs9939609, in the FTO gene showed a much stronger association with all-cause mortality than expected from its association with body mass index (BMI), body fat mass index (FMI) and waist circumference (WC). This finding implies that the SNP has strong pleiotropic effects on adiposity and adiposity-independent pathological pathways that leads to in
Previous studies using echocardiography in healthy subjects have reported conflicting data regarding the percentage of the stroke volume ( SV) of the left ventricle ( LV) resulting from longitudinal and radial function, respectively. Therefore, the aim was to quantify the percentage of SV explained by longitudinal atrioventricular plane displacement ( AVPD) in controls, athletes, and patients with
In 2009, a nationwide initiative was established in order to lead and develop world-leading research in Sweden. Lund University received strategic research funding from the Swedish Foundation for Stategic Research and the Swedish Government for 12 strategic research areas (SRAs) of excellence. Of these 12 SRAs, StemTherapy (the strategic research area for Stem Cells and Regenerative Medicine) cont
Kompetenscentret AdTherM inriktar sig på analyser av termiska processer i industriella tillämpningar, inklusive termo- och elektrokemisk energiomvandling. De flesta utmaningar för industrin inom detta område är generiska och baseras på samma fysiska mekanismer. För att utveckla detta forskningsfält måste både experiment och modeller förbättras och samordnas. AdTherM är en plattform som är centreraAdTherM targets analyses of thermal processes in industrial applications, including thermo- and electrochemical energy conversion activities. Most challenges for the industry in this area are generic and based on the same physical mechanisms. To develop this field, both experiments and models need to be improved and coordinated. AdTherM is a platform centered around the models and methods used t
By use of a batch microcalorimeter of the thermopile type, heat production was measured in isolated populations of human peripheral blood cells exposed to defined immune complexes formed in vitro. It was found that most of the heat production recorded in whole blood after admixture of immune complexes occurs in the granulocytes. Under these conditions small but constantly higher activation values
We are investigating how sensory information is transformed into neural signals using the fruit fly and the yellow fever mosquito as a model system.
Anorexia nervosa is a chronic, progressive illness that is difficult to treat. Four years after diagnosis, less than 50% of patients have recovered, and 25% of anorexic patients progress to chronicity and invalidism. Because anorexia nervosa typically begins in adolescence, teenagers should be watched closely for signs that may reflect an eating disorder. In the early stages of the disease, though
To understand why immune traits affect the fitness of its host is an important part of understanding why and how immune responses evolve. In threespine stickleback (Gasterosteus aculeatus), fibrosis is an immune response evolved to combat infection of the tapeworm parasite Schistocephalus solidus. Already known is that fibrosis leads to a reduced mating success for males. Here I investigated wheth
