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Endocrine resistant breast cancer is a major therapeutical challenge and accurate selection of patients susceptible to certain types of anti-hormonal treatment strategies is pivotal. Discovery of novel biomarkers potentially predicting treatment response as well as the clinical course of breast cancer is essential to effectively improve therapies and diagnosis. The main goal of this thesis was to
This paper contains a joint ESHG/ASHG position document with recommendations regarding responsible innovation in prenatal screening with non-invasive prenatal testing (NIPT). By virtue of its greater accuracy and safety with respect to prenatal screening for common autosomal aneuploidies, NIPT has the potential of helping the practice better achieve its aim of facilitating autonomous reproductive
We evaluated clinical significance of serum alpha-fetoprotein (AFP)-IgM immune complexes, in comparison with free AFP, on the diagnosis of primary hepatocellular carcinoma (HCC). Serum levels of AFP-IgM immune complexes and free AFP were determined by the ELISA method and electrochemiluminescence, respectively, in 103 healthy controls, 74 patients suffering from primary HCC, 27 patients suffering
In conjugated polymers the concept of spectroscopic units belonging to different spatial segments of the chain, which are responsible for the spectroscopic properties of the polymer, has been used to explain the spectral heterogeneity and the excitation migration by (Forster type) hopping transfer. In the present work we study the possible mechanism of segmentation of polythiophene into spectrosco
Popular Abstract in Swedish Avhandlingens titel är ju "Redovisning av goodwill". Därför kan det vara lämpligt att fråga sig vad de orden betyder i detta sammanhang. Goodwill har här inte den vanliga betydelsen av det goda anseende som exempelvis ett företag åtnjuter. Det är istället en benämning på skillnaden mellan värdet på hela företaget och summan av värdena på de enskilda tillgångarnaEvery conceivable manner of accounting, in the same country, at the same time! This is how-with no great exaggeration-the accounting of goodwill in Sweden in the late 1980s might well be described. Many companies still followed the Accounting Act, amortizing their goodwill over no more than ten years. Some, however, referred to the rules in the United States, extending the amortization peri
I projektet har ett verktyg eller metod för bestämning av risk i vårdavdelningar tagits fram. Verktyget, Brandskyddsvärdering av vårdavdelningar (BSV-vård) kan användas för att bestämma den relativa säkerheten för olika avdelningar vad avser brand. Meningen är att BSV-vård skall kunna användas som ett komplement vid brandsyn. Verktyget kan också tjäna som checklista vid nyproduktion då den också g
This thesis deals mainly with biocatalysed methods for stereoselective reduction. D-(S)-chlorolactic acid was produced by both microbial and electromicrobial reduction of chloropyruvate using whole cells of Proteus vulgaris and an artificial electron mediator. The electron donor was formate, hydrogen gas or the cathode in an electrochemical cell. Since chloropyruvate was susceptible to mediator de
This dissertation is about the antagonistic conceptions of men’s violence against women – rape, incest and physical assault – as has been expressed by different actors in Sweden from 1975 – 2000. Mainly, my interest lies in how and why these conceptions have been articulated. During the studied period the attention to men’s violence against women as a question of gender, has grown remarkably. For
The purpose of this study was to describe how life changes in psychotherapists’ own lives have affected their work. The topic was explored with a qualitative approach. The method was reflecting conversation. The result mainly illustrated how psychotherapists’ life changes and crises had affected them personally, rather than professionally. The psychotherapists mainly shared how life changes had le
År 2021 reformerades lagstiftningen gällande barns rätt att komma till tals i frågor om vårdnad, boende och umgänge. I 6 kap. föräldrabalken tillkom 2 b § som stadgar att barnet ska få information och ges möjlighet att framföra sina åsikter i frågor om vårdnad, boende och umgänge. Barnets åsikter ska tillmätas betydelse i förhållande till barnets ålder och mognad. Detta är den rättsliga utgångspun
I Sverige är straffbarhetsåldern 15 år vilket innebär att barn under 15 år kan begå brott men inte lagföras. En förundersökning kan då inte inledas. I stället kan en så kallad § 31 – utredning inledas vid de grövsta våldsbrotten. Till skillnad från vid en förundersökning saknas det idag rättsliga förutsättningar för målsägande att få juridiskt biträde vid en § 31 – utredningen. I utredningen ”FörbIn Sweden, the age of criminal responsibility is 15, which means that children under 15 can commit crimes but not be prosecuted. When this happens, a preliminary investigation, should not be held, but a so-called § 31 investigation can be held for the most severe crimes of violence. Unlike in the case of a preliminary investigation, there are currently no legal conditions for the injured party to
Feminist foreign policy initiatives have since they first appeared weathered criticism when put in relation to an active weapons export often to non-democratic states violating women’s rights. This paper then examines the Swedish case by using argumentation analysis as method to test the moral commitments of Sweden’s foreign policy initiative against recent arms deals. It was made to explore the p
This study aimed to investigate how counselors in primary care address the topic of suicide in conversations with patients. The intention was to examine whether the patient’s gender or age influenced how healthcare counselors inquire about suicide or address mental health issues. The method chosen for this study was qualitative interviews with seven counselors working in primary care in Sweden. In
Given the calls to examine accelerators across different regions and contexts, we ask the research question: How do accelerators adapt to institutional, social, and spatial constraints of emerging and established ecosystems? With this research question, we conduct qualitative research to understand how two different accelerators, one located in Skåne, Sweden and another located in Dhaka, Banglades
