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Proteins fold on a mu s-ms time scale. However, the number of possible conformations of the polypeptide backbone is so large that random sampling would not allow the protein to fold within the lifetime of the universe, the Levinthal paradox. We show here that a protein chain can fold efficiently with high fidelity if on average native contacts survive longer than non-native ones, that is, if the d
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As stakeholders struggle to reconcile calls for accountability and pressures for increased patient safety, criminal prosecution of surgeons and other health-care workers for medical error seems to be on the rise. This paper examines whether legal systems can meaningfully draw a line between acceptable performance and negligence. By questioning essentialist assumptions behind 'crime' or 'negligence
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This article presents one example of how masculinity and hierarchy are exercised through violence in organizations. It draws on the empirical data of 15 episodes from the US reality television series Hell’s Kitchen, in which 15 cooks compete for the job of Chef in one of celebrity chef Gordon Ramsay’s restaurants. Ramsay’s task is to lead the cooks towards a hegemonic masculinity valid in the rest
Pablo Pastor Vidal
Doktorand Kontaktinformation E-post: pablo [dot] pastor_vidal [at] jur [dot] lu [dot] se Telefon: +46 46 222 11 89Organisation Juridiska institutionen Rumsnummer: 230 Hämtställe: 56 WebbplatsPablo Pastor Vidals profil i Lunds universitets forskningsportalAndra roller Forskare Mänskliga rättigheter Profilområdesmedlem LU profilområde: Mänskliga rättigheter Forskare Folkrätt Publikationer Visar av p
https://www.jur.lu.se/pablo-pastor-vidal - 2026-06-29
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The inherent limitations of a specific pencil beam model have been studied when applied to a cylindrical geometry simulating the neck region. A comparison is made between measured and calculated absorbed dose in a cylindrical phantom. The goal is to quantify the deviations in the absorbed dose level, i.e., the dose per monitor unit, when photons are used for the treatment of head and neck tumours.
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The clinical diagnosis Of Multiple system atrophy (MSA) is fraught with difficulty and there are no pathognomonic features to discriminate the parkinsonian variant (MSA-P) from Parkinson's disease (PD). Besides the poor response to levodopa, and the additional presence of pyramidal or cerebellar signs (ataxia) or autonomic failure as major diagnostic criteria, certain other clinical features known
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The expected annual cost (in the year 2000 prices) for a 30-year-old patient with average individual and treatment characteristics for on-demand EUR 51 832 (95% CI: 44 324-59 341) and for prophylaxis EUR 146 118 (95% CI: 129 965-162 271), was obtained from panel-data analysis of an 11-year retrospective panel of 156 patients with severe haemophilia in Norway and Sweden. Costs included haemophilia-
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A novel disposable high-density matrix assisted laser desorption/ionization (MALDI) target plate made either from polymethylmethacrylate (PMMA) or polycarbonate (PC) is presented where thousands (1200-1600) of samples can be deposited and subsequently, analyzed by MALDI-time of flight (TOF) mass spectrometry. Good reproducibility, was obtained across the plate regardless of position on the target
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Instabilities in planetary systems can result in the ejection of planets from their host system, resulting in free-floating planets (FFPs). If this occurs in a star cluster, the FFP may remain bound to the star cluster for some time and interact with the other cluster members until it is ejected. Here, we use N-body simulations to characterize close star-planet and planet-planet encounters and the
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In a recent paper we presented a procedure for optimal analyticalcontrol of several deformable mirrors based on only the measured guidestar wavefronts. The expected performance was evaluated for variousguide star configurations using up to three deformable mirrors. Forsimplicity the guide stars were assumed to be infinitely distant. Inthis paper we address the effect of using laser guide stars in
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Emissions from the combustion of fossil fuels contribute to the greenhouse effect around the globe. It is therefore of great interest to reduce the use of fossil fuels and revert to some form of biofuel. Lignin, extracted from kraft black liquor, has the potential to become a significant contributor to the biofuel market. A modern pulp mill has an energy surplus that can amount to 7 GJ per tonne o
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Using judges and stage actors as instructive polar types this article elucidates factors that influence the inclination to empathise. Both come in close contact with dramatic life stories on an everyday basis but approach empathy from contrasting vantage points: emotional distance versus emotional engagement. Similarities between these polar types can thus disentangle some of the factors that inflUsing judges and stage actors as instructive polar types this article elucidates factors that influence the inclination to empathise. Both come in close contact with dramatic life stories on an everyday basis but approach empathy from contrasting vantage points: emotional distance versus emotional engagement. Similarities between these polar types can thus disentangle some of the factors that infl
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Climate change presents significant threats to human health, especially for low-income urban communities in the Global South. Despite numerous studies of heat stress, surprisingly little is known about the temperatures actually encountered by people in their homes, or the benefits of affordable adaptations. This paper examines indoor air temperature measurements gathered from 47 living rooms withi
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Social trust is a moral resource with a normatively highly desirable pay-off. Previous research argues that universal welfare state programmes ‘make’ social trust whereas means-testing programmes ‘break’ it. Despite its important implications for welfare-state design, comparative longitudinal evidence for this hypothesis is scarce. To test whether within-country changes in social trust are associa
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There is limited understanding of how education initiatives geared toward faculty and support staff can foster a capacity for long-term and integrated societal engagement and collaboration within higher education institutions. Using the experiences from a cross-disciplinary pilot course in Sweden, the current study aims to identify features that explicate how skills and academic rigor for engaging
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The Storage Location Assignment Problem (SLAP) has a significant impact on the efficiency of warehouse operations. We propose a multi-phase optimizer for the SLAP, where the quality of an assignment is based on distance estimates of future-forecasted order-picking. Candidate assignments are first sampled using a Markov Chain accept/reject method. Order-picking Traveling Salesman Problems (TSPs) ar
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Background: The period after a child is discharged from hospital is generally described as challenging for the parents. Their satisfaction with the health services received is an important indicator of the quality of care. eHealth devices are increasingly used in health care to support communication with parents. Differences in levels of parental satisfaction by modality of provided care or by par
