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Abstract Background. Proteinuria is the hallmark of glomerular disease and non-selective proteinuria is often associated with progression to renal failure. The predictive value of urine IgG excretion was studied comprehensively in patients with nephrotic syndrome. In the present follow-up study, we examine the predictive value of IgG-uria in patients with idiopathic glomerular diseases with a wide
Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1
Dark matter accounts for about 85% of all matter in the Universe, yet its particle nature remains unknown. The Light Dark Matter eXperiment (LDMX) is a proposed fixed-target missing-momentum experiment that intends to probe the predominantly experimentally uncharted MeV-GeV mass range for "light dark matter". A significant challenge for LDMX is to efficiently veto rare photo-nuclear back
The houses from the million homes program are in severe need of renovation. A problem that arises when housing companies renovate are extreme rent increases. In many instances it exceeds the tenants’ payment ability. Resulting in a renoviction process where the tenant has no choice but to move. This study aims to examine how the housing company Fastigheter AB Trianon has worked with these necessar
Reducing microorganisms by UV light is has been commonly used for drinking water for many years. In other liquid products like apple juice it is a rather novel application. The advantages would be that quality parameters like aromas and vitamins are less affected by the UV treatment compared to a heat treatment. Furthermore it would probably be cheaper, as the lamps need less electrical energy tha
The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage
Venous thromboembolism (VTE) clusters in families, but the familial risk of VTE has only been determined in first-degree relatives. This nationwide study aimed to determine the familial risk of VTE in first-, second- and third-degree relatives of affected individuals. The Swedish Multi-Generation Register was linked to Hospital Discharge Register data for the period 1987-2009. This was a case-coho
Objective. To analyse the management of muscle-invasive bladder cancer in a population-based national register, and specifically to investigate the role of curative therapy (i.e. cystectomy or radiotherapy) in relation to patient, tumour and hospital characteristics. Material and methods. The Swedish Bladder Cancer Register covers more than 90% of all patients in the country who have been diagnose
Background and Purpose-Although many stroke patients are young or middle-aged, risk factor profiles in these age groups are poorly understood. Methods-The Stroke in Young Fabry Patients (sifap1) study prospectively recruited a large multinational European cohort of patients with cerebrovascular events aged 18 to 55 years to establish their prevalence of Fabry disease. In a secondary analysis of pa
Cathepsin E (CTSE), an aspartic proteinase, is differentially expressed in the metaplasia-dysplasia-neoplasia sequence of gastric and colon cancer. We evaluated CTSE in Barrett's esophagus (BE) and cancer because increased CTSE levels are linked to improved survival in several cancers, and other cathepsins are up-regulated in BE and esophageal adenocarcinoma (EAC). A total of 273 pretreatment tiss
Objectives High-risk human papillomavirus (hrHPV) is the primary cause of cervical cancer. As Chlamydia trachomatis is also linked to cervical cancer, its role as a potential co-factor in the development of cervical intraepithelial neoplasia (CIN) grade 2 or higher was examined. Methods The placebo arms of two large, multinational, clinical trials of an HPV6/11/16/18 vaccine were combined. A total
BACKGROUND: Insulin resistance was found in some but not in all previous studies of non-diabetic first degree relatives of Type 2 diabetic patients. Small study groups, ethnic differences and/or non-optimal techniques may explain the conflicting results. AIM: To study the impact of a family history of Type 2 diabetes on insulin action in a large group of non-diabetic Europeans using the 'gold stan
The neutron beam at the Studsvik facility for boron neutron capture therapy (BNCT) and the validation of the related computational model developed for the MCNP-4B Monte Carlo code are presented. Several measurements performed at the epithermal neutron port used for clinical trials have been made in order to validate the Monte Carlo computational model. The good general agreement between the MCNP c
With the post-Kyoto climate negotiations underway, global emissions must be cut by 66% by, 2050 according to the IPCC, to prevent further damage to the environment. In order for this emission cut to be possible, all nations have to be a part of these negotiations. The Kyoto Protocol and the UNFCCC is the natural starting point for a new climate regime that must be established. Through a literatur
With the development of society the risks have become more complex and difficult to overview. Not least because of the inter¬dependencies that exist between them. This master thesis aims to study critical societal functions dependencies in the primary care in Skåne and to investigate the possibility of intro¬ducing some kind of basic security levels in those functions. The study includes four main
Connecting science to political agenda-setting is essential for a sustainable transition and acceptable politics. This task is complicated by phenomena like post-truth, for which facts are a non-issue. However, post-truth is not the only issue. The practice of political spin, in which the significance of facts is reconstructed according to specific interests poses another threat to scientific cred
The purpose of this thesis is to further the knowledge of the Internet’s effect on trade. The study is conducted by examining the specific example of the introduction of the SAT-3/WASC submarine Internet cable in Benin. The research is conducted by using a Difference in Difference estimator and observing the treatment effect of the Internet cable on the country’s exports. Previous studies have mo
Although there is a well-researched theoretical tradition to explain institutional trust, very little research has been done in authoritarian countries in general, and MENA countries more specifically. This study aims to fill this gap in the literature by identifying the factors that explain institutional trust in Algeria, focused more specifically on Algeria’s armed forces as one of the powerbrok
