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Is the EQ-5D a Valid Instrument to Assess Health Related Quality of Life of Psoriasis Patients?

The purpose of this paper was to investigate whether EQ-5D is a valid measure of Health Related Quality of Life of psoriasis patients. The objective was carried out by investigating the correlation between the EuroQol EQ-5D and two other Health Related Quality of Life measures, Dermatology Life Quality Index and a Visual Analogue Scale assessed by the patient, as well as two clinical outcome measu

"Islamofobi är det nya skrämselordet" En idénalays av den kritisk humanistiska diskursen

In Sweden opinions are strongly divided on the issue of integration. In a study from 2007 four parallel discourses on integration in the Swedish debate were identified. They are labeled the liberal-, the social democratic-, the structural discrimination discourse and finally a discourse of assimilation. A fifth is discussed briefly – the critical humanist position. In this report I take a closer l

Risk Analysis and Management of IT Systems: Practice and Challenges

Risk analysis is important for safety-critical IT systems and services, both in public and private organizations. However, the actual practices and the challenges of risk analysis in these contexts have not been fully explored. This paper investigates the current practices of risk analysis by an interview-based investigation. This study investigates several factors of the risk analysis process, e.Risk analysis is important for safety-critical IT systems and services, both in public and private organizations. However, the actual practices and the challenges of risk analysis in these contexts have not been fully explored. This paper investigates the current practices of risk analysis by an interview-based investigation. This study investigates several factors of the risk analysis process, e.

Comparing Life Cycle Costing and Performance Part Costing in Assessing Acquisition and Operational Cost of New Manufacturing Technologies

Even if practitioners want to adopt new manufacturing technologies, there is a lack of comprehensive tools to support their decisions, regarding both cost and sustainability. This paper reviews and compares the practical use of Life Cycle Costing (LCC) with a performance part costing (PPC) model, chosen based upon the criteria of providing in-depth analysis capabilities and the prospect of integraIn today’s business environment, the trend towards more product variety and customization is unbroken. Due to this development, the need of agile and reconfigurable production systems emerged to cope with various products and product families. To design and optimize production systems as well as to choose the optimal product matches, product analysis methods are needed. Indeed, most of the known m

Benchmarking Medical Research - Aggregating Publications using Medical Subject Headings (MeSH-terms)

As the interest in research performance analysis using bibliometrics increases, more specialised tools are developed. In cases when verified publication data is not available; data is normally collected and aggregated using subject or organisational criteria. The journal subject areas in Thomson Reuters/ISI are often used, but can be poor in their precision and granularity. In an attempt to improv

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries : a multicentre, international, prospective cohort study

Background: Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anoma

DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously

We report the development of a platform of dual targeting Fab (DutaFab) molecules, which comprise two spatially separated and independent binding sites within the human antibody CDR loops: the so-called H-side paratope encompassing HCDR1, HCDR3 and LCDR2, and the L-side paratope encompassing LCDR1, LCDR3 and HCDR2. Both paratopes can be independently selected and combined into the desired bispecifWe report the development of a platform of dual targeting Fab (DutaFab) molecules, which comprise two spatially separated and independent binding sites within the human antibody CDR loops: the so-called H-side paratope encompassing HCDR1, HCDR3 and LCDR2, and the L-side paratope encompassing LCDR1, LCDR3 and HCDR2. Both paratopes can be independently selected and combined into the desired bispecif

Satisfaction among non-conveyed patients and significant others when discharged at the scene by the ambulance service: an exploratory cross-sectional survey

BackgroundThe ambulance service is facing an increased number of calls and ambulance assignments. Between 12 and 42% of all assignments result in non-conveyance to the Accident and Emergency Department. However, there is limited knowledge regarding satisfaction among patients and significant others when patients are assessed as non-urgent and discharged at the scene. Therefore, the aim of the studBackgroundThe ambulance service is facing an increased number of calls and ambulance assignments. Between 12 and 42% of all assignments result in non-conveyance to the Accident and Emergency Department. However, there is limited knowledge regarding satisfaction among patients and significant others when patients are assessed as non-urgent and discharged at the scene. Therefore, the aim of the stud

Fast-track Sociology? Reflections on Research During a Pandemic

When the coronavirus spread globally in early 2020, many governments issued national lock downs of schools, institutions, and businesses. As the epidemic turned into a pandemic, the health crisis also became a societal crisis, and many universities and research foundations issued COVID-19 grants to study the societal implications of the crisis. In this article, we discuss sociological research dur

Snoilskys Svenska bilder i skolan och kulturminnets förändringar

The article investigates the reception of Carl Snoilsky’s Svenska bilder (Swedish Pictures) in Swedish schools, from the 1890s until today, in the light of the concept of cultural memory. For more than half a century, Snoilsky’s cycle of poems, depicting important events and figures in Sweden’s early modern history, belonged to the literary school canon; three special school editions were publishe

From Apathy to Activism: Tracing the Changing Political Attitudes and Behaviours among Young Kenyans

This thesis investigates the evolving political attitudes and behaviours toward democracy among young Kenyans, examining whether they are becoming increasingly apathetic toward democracy or are evolving innovative democratic behaviours. Using a mixed-methods approach, the research combines quantitative data from Afrobarometer surveys with qualitative interviews with Kenyan youths conducted during

Economic Growth, Innovation and Government R&D: A Case Study on the German Nuclear Sector

This paper looks at the potential economic outcomes of Germany’s Anti- Nuclear policies, especially the policies of the early 2000’s and those made in 2011 in the wake of the Japanese nuclear disaster at Fukushima, in which research and development (R&D) funding has been increasingly shifted away from the nuclear sector. This paper discusses the German case after it is established through theo

The Granger causal relationship between energy consumption and economic growth for eight European countries

Motivated by the rising importance of today’s environmental issues and more specifically the role of energy conservation policies, the current study investigates the Granger causal relationship between energy consumption and economic growth in eight European countries. Using a large dataset that overall spans from 1800-2009 the study employs the Toda-Yamamoto procedure and cointegration analysis w

Studies of removal of 210Po, 234U, 238U and 137Cs in man by dialysis

Mat som kontaminerats av radionuklider genom till exempel radioaktivt nedfall kan ge höga stråldoser till kroppen. Nuklider med långa halveringstider kan ackumuleras i kroppen och ge en hög tidsintegrerad absorberad dos. Personer med kronisk njursvikt kan erhålla höga stråldoser efter intag av radionuklider eftersom många radionuklider utsöndras via njurarna. I den här undersökningen har vi studerHigh internal radiation doses can result from food, contaminated by radionuclides from for example nuclear fallout. Nuclides with long half-lifes can accumulate in the body and give a high time-integrated absorbed dose. Persons with end-stage renal disease can receive high absorbed doses after intake of radionuclides, since many radionuclides are mainly excreted by the kidneys. In this study the d

Echoes of Distress: Maternal Malaise and the Pathways of Intergenerational Socioeconomic Outcomes

This study investigates how early exposure to maternal mental distress shapes offspring’s long‐ term socioeconomic pathways by leveraging the 1970 British Cohort Study. Maternal distress was measured when the cohort members were aged 5, 10, and 16 years via the 24-item Malaise Inventory. Structural Equation Modeling is employed to estimate (1) the direct effect of maternal malaise on offspring’s a

The emotion regulation of performance work

This chapter explores performances of emotion regulation through a dramaturgical lens, focusing on occupations with high performative demands. While reviewing research and theorizing on performance, we point to key intersections between sociological studies on emotion management and psychological studies on emotion regulation. First, we focus on the scaffolding of performance, how the script and t

Concizumab prophylaxis in people with haemophilia A or haemophilia B without inhibitors (explorer8) : a prospective, multicentre, open-label, randomised, phase 3a trial

Background: Concizumab is an anti-tissue factor pathway inhibitor monoclonal antibody in development as a once-daily, subcutaneous prophylaxis for patients with haemophilia A or haemophilia B with or without inhibitors. We aimed to assess the efficacy and safety of concizumab in patients with haemophilia A or B without inhibitors. Here we report the results from the confirmatory analysis cutoff. M