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Popular Abstract in Swedish De flesta produkter som vi dagligen använder tillverkas genom att utnyttja fossila råvaror som olja, kol och naturgas. Ett stort problem är att dessa råvaror bara finns i begränsade mängder i naturen, vilket medför att de förr eller senare tar slut. Dessutom medför förbränning av fossila råvaror att det bildas miljöskadande gaser (t.ex. koldioxid) som ansamlas i atmosfäOne of the major challenges facing the world today is the reduction of our dependency on fossil resources as their exploitation has severe negative effects on the environment. One way of realizing this is to utilise the components of lignocellulosic biomass to a greater extent as feedstock for various industrial products. However, such utilisation requires the extraction of the biopolymers from th

BACKGROUND CONTEXT: Several studies report a favorable short-term outcome after nonoperatively treated two-column thoracic or lumbar burst fractures in patients without neurological deficits. Few reports have described the long-term clinical and radiological outcome after these fractures, and none have, to our knowledge, specifically evaluated the long-term outcome of the discs adjacent to the fra

Metabolic stress is a phenomenon often discussed in conjunction with recombinant protein production in Escherichia coli. This investigation shows how heterologous protein production, and the presence of host cell proteases is related to: i) IPTG induction, ii) cell mass concentration at the time of induction and iii) the presence of metabolites (glutamic acid or those from TSB) during the post ind

Background: Combination lipid-lowering therapy (LLT) after myocardial infarction (MI) achieves lower low-density lipoprotein cholesterol (LDL-C) levels and better cardiovascular outcomes vs statin monotherapy. As a result, global guidelines recommend lower LDL-C but, paradoxically, advise treatment through a stepwise approach. Yet the need for combination therapy is inevitable as <20% of patients

The power extracted by reverse electrodialysis (RED) is often limited by the high resistance of low concentration compartment. This work aims to address this issue by demonstrating a reverse electrodeionization (REDI) design that can facilitate the ion transport and alleviate so called spacer shadow effects. In total, three different stack designs were assembled by substituting the conventional sp

BACKGROUND: The rationale for ethnic differences in bladder cancer (BCa) susceptibility is an important open question. In this study, we raised the hypothesis that the APOBEC3-rs1014971 variant associated with BCa risk and APOBEC-mutagenesis probably contribute to ethnic differences. METHODS: We calculated the ethnicity-stratified 5-year age-adjusted incidence rates of BCa using the US SEER databa

Abstract Co-operation difficulties in the work place can be a problem serious enough. Co-operation difficulties can occur between employee and employer, as well as employees among themselves. Irrespective of between which individuals the co-operation difficulties occur, it will have negative consequences. These can consist of, for example that individuals might suffer mentally, inproductivity and

Tetra Pak is continuously working to increase the efficiency of the whole organisation. There is currently a general demand to improve by 20%. The number is not to be taken literately since efficiency is not defined nor is it specified how it should be measured. At Tetra Top the interpretation is that it is important to focus on efficiency and that it is up to individuals how and when it can be at

Background: Cognitive impairment is common following out-of-hospital cardiac arrest (OHCA), but the nature of the impairment is poorly understood. Our objective was to describe cognitive impairment in OHCA survivors, with the hypothesis that OHCA survivors would perform significantly worse on neuropsychological tests of cognition than controls with acute myocardial infarction (MI). Another aim was

Background: The failing heart is traditionally described as metabolically inflexible and oxygen starved, causing energetic deficit and contractile dysfunction. Current metabolic modulator therapies aim to increase glucose oxidation to increase oxygen efficiency of adenosine triphosphate production, with mixed results. Methods: To investigate metabolic flexibility and oxygen delivery in the failing

Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-year period. Methods: Patients with follow-up and tumor samples, treated between 1990 and 2010, in 93 centers/9 countries. Samples w

BACKGROUND: Breast cancer in young adults has been implicated with a worse outcome. Analyses of genomic traits associated with age have been heterogenous, likely because of an incomplete accounting for underlying molecular subtypes. We aimed to resolve whether triple-negative breast cancer (TNBC) in younger versus older patients represent similar or different molecular diseases in the context of g

Popular Abstract in Swedish För att minska CO2-utsläppen från godstransporter har politiker i Europa under de senaste tio åren framhävt att det krävs ett skifte i transportslag för europeiska transporter, från flyg- och lastbilstransporter till mer miljövänliga tåg- och sjötransporter. Intermodala väg-järnvägstransporter, där en kombination av tåg och lastbil använts för att förflytta lösa standarAmong policy-makers in Europe the modal shift - a shift från polluting modes of freight transport to less polluting modes - has been a popular suggestion for reducing CO2-emissions of transportation. In particular, intermodal road-rail solutions, where a combination of road and rail transport is utilized to move trailers and containers, have been stressed as an important measure to reach de desire

Importance: This follow-up study of extremely preterm (EPT) children (<27 weeks' gestational age [GA] at birth) revealed major eye and visual problems in 37.9% (147 of 388) of all EPT infants and in 55.4% (67 of 121) of the most immature subgroups at 6.5 years of age. These major eye and visual problems were strongly associated with treatment-requiring retinopathy of prematurity (ROP).Objectives:

An ongoing continuous process of automatization of the production lines is used in industry to reduce production costs. Automatization of quality control should be seen as part of a cost reduction process, as well as of quality control of the welding. Mostly the time-consuming and expensive checking procedure of the weld joint is carried out off-line by an experienced welding operator. The need fo

Popular Abstract in Swedish Hormonerna vasopressin och oxytocin frisätts från hypofysens baklob. Hypofysen är en körtel, som är belägen på undersidan av hjärnan och utsöndrar en rad olika hormoner vilka i sin tur påverkar och reglerar aktiviteten i en mängd andra organ. Vasopressin medverkar till regleringen av vatten- och saltbalansen i kroppen, men verkar också sammandragande på icke-viljestyrdVasopressin and oxytocin seem to have pivotal roles in the pathophysiology of primary dysmenorrhoea and preterm labour. Prostaglandins are also involved in the regulation of uterine activity with different receptors mediating both stimulation and relaxation. We explored different aspects of synthesis, release and receptor pharmacology of vasopressin and oxytocin. We also tested a vasopressin and o

Objective: The aim of this systematic review and meta-analysis (SR-MA) was to identify signaling molecule profiles and blood-derived biomarkers in migraine and cluster headache (CH) patients. Background: Currently no migraine and CH valid biomarkers are available. Blood tests based on biomarker profiles have been used to gather information about the nervous system. Such tests have not yet been est