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BACKGROUND: Abiraterone acetate plus prednisone significantly improved radiographic progression-free survival compared with placebo plus prednisone in men with chemotherapy-naive castration-resistant prostate cancer at the interim analyses of the COU-AA-302 trial. Here, we present the prespecified final analysis of the trial, assessing the effect of abiraterone acetate plus prednisone on overall s

BACKGROUND: Antibacterial peptidyl derivative - Cystapep 1, was previously found to be active both against antibiotic-resistant staphylococci and streptococci as well as antibiotic-susceptible strains of these species. Therefore, it is a promising lead compound to search for new antimicrobial peptidomimetics.OBJECTIVES: We focused on identifying structural elements that are responsible for the bio

Ecological compensation is the latest member of a growing family of concepts aimed at reducing degradation of environmental quality. This and other concepts of the family – like ecosystem services, green infrastructure, and nature-based solutions – have been subject to a range of different interpretations and subsequent implementation practices. The result is a complex governance system with uncle

Solid grafts of autologous superior cervical ganglia (SCG) or fetal locus coeruleus (LC) were implanted unilaterally into a fimbria-fornix lesion cavity adjacent to the hippocampal formation after a 6-hydroxydopamine lesion of the intrinsic noradrenergic system. Twelve to 15 months after transplantation, one microdialysis probe was implanted in the dorsal hippocampus ipsilateral to the graft, and

The European Open Science Cloud is a pan-European initiative that aims at developing a federated infrastructure that supports scientific research and Open Science. Having the FAIR principles at the core of Open Science practices, the Environmental Research Infrastructures (ENVRIs) that operate in Europe collaborate at cluster level (the ENVRI cluster) continuously improving the FAIRness of their s

Information relating to errors in evapotranspiration (ET) products, including satellite-derived ET products, is critical to their application but often challenging to obtain, with a limited number of flux towers available for the sufficient validation of measurements. Triple collocation (TC) methods can assess the inherent uncertainties of the above ET products using just three independent variabl

The European project ‘REsilient WAter Innovation for Smart Economy’ (REWAISE) aims to establish a novel ‘smart water ecosystem’ by integrating an advanced digital infrastructure for decentralized water services and decision-making, engaging all stakeholders to highlight the actual value of water. The approach will reduce the consumption of freshwater and energy while also recovering valuable nutri

Radiation protection professionals are engaged in risk communication with various stakeholders to contribute to risk awareness, trust building, informed risk decisions, and advice for action. The newly launched IRPA guideline on risk communication has the objective to enthuse communication on radiation protection and provide experiences and techniques regarding this task. However, radiation protec

This conceptual chapter investigates how knowledge moves across different “social fields” (Bourdieu, 2005b). We propose a certain social Gestalt new knowledge discussion creates the dialogically constructed antenarrative field. An antenarrative field is a social space for knowledge exchange where agents speculate on future scenarios’ potential for realization, and our notion of the antenarrative f

The World Energy Council ranks the Danish energy system among best in the world judging by the energy trilemma criteria: energy security, energy equity, and sustainability. District heating (DH) and CHPs are pivotal for this ranking. This brief historical account illustrates how a mix of historical events, collective societal experiences, cultural and political values inform the Danish history of

Importance: Meningioma is the most common subsequent neoplasm following cranial irradiation among survivors of childhood cancer, but there are still uncertainties regarding the magnitude of the radiation dose-response association, potential modifiers of radiation risks, and the role of chemotherapy. Objective: To evaluate meningioma risk in survivors of childhood cancer following radiotherapy and

This article is about psychiatric patients’ life stories. I explore how best to handle patient narratives in the history of medicine and, more specifically, in the history of psychiatry. By applying a narrative and phenomenological analysis – seldom used in historical studies of psychiatry and psychiatric care – the aim is a new understanding of patient stories both as historically situated and as

Microsoft Word - Final report from SWEAH External Advisory Board.doc 1 Second report from SWEAH External Advisory Board June 2019 Søren S.E. Bengtsen, Dorly Deeg, Lars Geschwind (chair) Introduction This is the second and final report from the SWEAH External Advisory Board (EAB). It is based on our understanding of the structures, processes and outcomes of SWEAH during the period of study (2017-20

https://www.sweah.lu.se/sites/sweah.lu.se/files/sweah_eab_second_report.pdf - 2026-06-19

Science Journals — AAAS REVIEW SUMMARY ◥ OXYGEN SENSING Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity Emma U. Hammarlund*†, Emily Flashman, Sofie Mohlin, Francesco Licausi*† BACKGROUND:Animals and land plants are the most diverse complex multicellular life-forms on Earth, and their success intricately links a capacity for adhering cells to perform

https://www.tcr.lu.se/sites/tcr.lu.se/files/2020-11-16_hammarlund_et_al_2020.pdf - 2026-06-19

929 Proficiency Testing of Human Leukocyte Antigen-DR and Human Leukocyte Antigen-DQ Genetic Risk Assessment for Type 1 Diabetes Using Dried Blood Spots Paul Dantonio, M.S.,1 Nancy Meredith-Molloy, B.S.M.T., M.T.(ASCP),1 William A. Hagopian, M.D., Ph.D.,2 Jin Xiong She, M.D., Ph.D.,3 Beena Akolkar, Ph.D.,4 Suzanne K. Cordovado, Ph.D.,1 Miyono Hendrix, B.S.,1 L. Omar Henderson, PhD.,1 W. Harry Hann

https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_08_dantonio_jdst_2010.pdf - 2026-06-19

Children are not only negatively affected by being exposed to violence themselves, but they are also affected by witnessing violence. For example, mental health issues and not getting the support that they need. In 2021, the law “barnfridsbrott” came into effect, making it illegal to allow a child to witness violence between people they have a close relationship with. This study is about the conce

Som en del i utvecklingen mot grönare och miljövänligare processer, samt ett behov av ytterst specifika reaktioner, vill AAK AB utvidga sin användning av lipaser i sin produktion av strukturerade triacylglyceroler (STAGs). AAK vill bygga upp ett bibliotek av utvärderade lipaser. Syftet med detta examensarbete är att bidra till detta bibliotek genom att karakterisera en grupp kommersiellt tillgänglAs part of a switch towards more green and environmentally friendly processes, together with a need for highly specific reactions, AAK AB wants to broaden their use of lipases in the production of structured triacylglycerols (STAGs). AAK are working on creating a lipase library where several lipases are evaluated, this master thesis aims to contribute to this lipase library by characterizing a sel

Uppsatsens syfte är att undersöka hur transformativa verk behandlas inom den svenska upphovsrätten. I centrum för informationssamhället uppenbarar sig en grundläggande motsättning mellan å ena sidan internetkulturens kultur av fri tillgång, spridning och användning, å andra sidan upphovsrättens över- gripande mål att skydda och kontrollera spridningen och användningen av upphovsrättsskyddade verk.The purpose of the essay is to examine how transformative works are treated within Swedish copyright law. At the center of the information society, a fun- damental contradiction emerges between, on the one hand, the Internet cul- ture's stamp of free access, dissemination and use, and on the other hand, cop- yright's overarching goal of protecting and controlling the dissemination and use

The aim of this study was to explore how professionals working with the evidence-based method Individual Placement and Support (IPS) reason regarding its utilization for a broader target audience than the method originally intended. Additionally, we sought to enhance the understanding of how and why an evidence-based method is modified and adapted when applied in a new setting and for a different

Bakgrund Muskelaktivering och muskelkraft i quadriceps påverkas av bland annat knävinkeln. Sambandet mellan dessa är inte fastställt. Elektromyografi (EMG) används för att undersöka muskelaktivering och ge information om muskelaktivering och muskeltrötthet. Vridmomentet beräknas genom kraft multiplicerat med hävarm. Syfte Syftet med denna studie var att undersöka aktivering av de ytliga quadriceps