Search results

Several organic cations, such as guanidino compounds and polyamines, have been found to accumulate in plasma of patients with kidney failure due to inadequate renal clearance. Here, we studied the interaction of cationic uremic toxins with renal organic cation transport in a conditionally immortalized human proximal tubule epithelial cell line (ciPTEC). Transporter activity was measured and valida

Giant bamboo plantations are currently being established in the Southern Africa region and can be considered as potential lignocellulosic feedstock for the production of second generation bioethanol. In this study, giant bamboo internodal material was subjected to sulphur dioxide (SO2) impregnated steam pretreatment prior to enzymatic hydrolysis. The effect of temperature, residence time, and acid

Background: A delay in surgical nerve repair results in impaired nerve function in humans, but mechanisms behind the weakened nerve regeneration are not known. Activating transcription factor 3 (ATF3) increases the intrinsic growth state of injured neurons early after injury, but the role of long-term changes and their relation to axonal outgrowth after a delayed nerve repair are not well understo

Nanoparticles made from recombinant proteins offer excellent potential for several nanotechnological applications. However, only a very limited number of proteins are currently being used for such purposes due to limited availability and stability. Therefore, we have investigated the enamel matrix protein amelogenin as a new alternative protein for use as recombinant nanoparticles. Amelogenin is a

Precision error of dual-energy X-ray absorptiometry exceeds the expected annual rate of bone loss in the elderly. The capacity to detect changes in areal bone mineral density (aBMD; g/cm(2)) over a 5-yr period was assessed. Six hundred ninety-one women, 75.2 (0.1)yr, from the Malmö OPRA-study, were measured using Lunar DPX-L (GE Lunar, Madison, WI), and 211 men, 74.7 (3.2)yr, from the Malmö Mr Os-

BACKGROUND: Degranulation of eosinophils in target tissues is considered a key pathogenic event in major chronic eosinophilic diseases. However, because of a lack of appropriate methods, little is known about degranulation of eosinophils in common eosinophilic diseases. METHODS: Using transmission electron microscopic (TEM) analysis, a novel approach has been devised and validated to quantify eosi

This thesis highlights the research and development of a new plastic-scintillator detector for time-of-flight measurements in relativistic heavy-ion beam experiments. The detector makes possible the identification of different ion species on flight distances as short as a few meters. The novelty lies in the design approach of using many moderately fast, independent measurements of every physical e

A shear-enhanced, cross-flow ultrafiltration module was used to separate cells and proteins from the fermentation broth. Three (fermented) media were studied: rich medium, rich medium with hydrolytic enzymes added after fermentation, and wheat flour hydrolysate. To find a membrane with as high a flux as possible, but still capable of separating cells and proteins from the lactic acid containing br

A recently developed ultrasound phase-locked echo-tracking system makes it possible to measure non-invasive pulsatile vessel diameter changes, and, in combination with blood-pressure measurement, to calculate pressure strain elastic modulus (Ep) and stiffness (beta). The reproducibility in measurements of pulsatile diameter changes with this system was evaluated. Also the precision of indirect blo

Popular Abstract in Swedish Avhandlingen består av tre delar. Den första, Från utbildningsmarknad till of-fentlig utbildning. Svensk flickskola 1874-1962, behandlar dels integrationen av flickornas sekundärutbildning i den offentliga utbildningsorganisationen, dels förstärkningen respektive försvagningen av denna speciellt genuskodade utbild-ning. Sekundärutbildningen har varit könssegregerad och The thesis is divided into three sections. The first, “From an education market to public education. The Swedish girls’ school 1874-1962”, deals with the integration of girls’ secondary education into the public education system, as well as with the strengthening and weakening of this special, gender-coded education. Secondary education was gender segregated and integration involved a process of s

The aim of this population-based prospective study was to determine the incidence of limb fracture by site and gender in different regions of Europe. Men and women aged 50-79 years were recruited from population registers in 31 European centers. Subjects were invited to attend for an interviewer-administered questionnaire and lateral spinal radiographs. Subjects were subsequently followed up using

In Sweden and elsewhere in the world the construction industry has encountered criticism due to its lower productivity gains in comparison to other industries. This is why continual improvement of processes and forms of cooperation are important, as is utilisation of technologies giving greater efficiencies. The focus in Sweden has mainly been on the construction of multifamily buildings, both bec

Traumatic brain injury (TBI) constitutes a global epidemic. Overall outcome is poor, with mortality ranging from 10 to 70% and significant long-term morbidity. Several experimental reports have claimed effect on traumatic edema, but all clinical trials have failed. Antisecretory factor, an endogenous protein, is commercially available as Salovum®, which is classified as a medical food by the Europ

Warm periods in Earth's history offer opportunities to understand the dynamics of the Earth system under conditions that are similar to those expected in the near future. The Middle Pliocene warm period (MPWP), from 3.3 to 3.0 My B.P, is the most recent time when atmospheric CO2levels were as high as today. However, climate model simulations of the Pliocene underestimate highlatitude warming that

From the 6th to the 9th of November 2016, in the meeting hall of Centro Nacional de Aceleradores(University of Seville, Seville, Spain) took place the “II International Conference onRadioecological Concentration Processes (50 years later)” under the joint organization of theUniversities of Seville (Spain) and Gothenburg (Sweden). With this event, the organization try tocommemorate the fifty years

BACKGROUND:: Iraqi-born immigrants residing in Sweden are at high risk for type 2 diabetes, obesity and hyperlipidemia compared with native Swedes. Paradoxically, hypertension is less prevalent in this immigrant population. The aim of this study was to investigate differences in renal function and further if differences in blood pressure (BP) levels were associated with differences across ethnicit

The Neptunian satellite system is unusual, comprising Triton, a large (∼2700 km) moon on a close-in, circular, yet retrograde orbit, flanked by Nereid, the largest irregular satellite (∼300 km) on a highly eccentric orbit. Capture origins have been previously suggested for both moons. Here we explore an alternative in situ formation model where the two satellites accreted in the circum-Neptunian d

Objectives To investigate, using a Dutch model, whether and under what variables framed for other European countries screening for human papillomavirus (HPV) is preferred over cytology screening for cervical cancer, and to calculate the preferred number of examinations over a woman's lifetime. Design Cost effectiveness analysis based on a Dutch simulation model. Base case analyses investigated the

Spatial distribution information on population density is essential for understanding urban dynamics. In recent decades, remote sensing techniques have often been applied to assess population density, particularly night-time light data (NTL). However, such attempts have resulted in mapped population density at coarse/medium resolution, which often limits the applicability of such data for fine-sca

BACKGROUND: The possible excess of congenital malformations in infants born after in vitro fertilization (IVF) has been much discussed in the literature, with controversial conclusions. This population based study is aimed at analyzing the presence of congenital malformations in a large group of infants born after IVF and to compare malformation risk both with that of all infants born and accordin