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β-Mannan degradation by gut bacteria - Characterization of β-mannanases from families GH5 and GH26
Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s
Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata
The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers
Long-term tobacco smokers with chronic obstructive pulmonary disease (COPD) or chronic bronchitis display an excessive accumulation of neutrophils in the airways; an inflammation that responds poorly to established therapy. Thus, there is a need to identify new molecular targets for the development of effective therapy. Here, we hypothesized that the neutrophil-mobilizing cytokine interleukin (IL)
TLR4-mediated release of heparin-binding protein in human airways : a co-stimulatory role for IL-26
Late Pleistocene glacial history of Jameson Land, central East Greenland, derived from cosmogenic (10)Be and (26)Al exposure dating
Abstract in Undetermined Previous work has presented contrasting views of the last glaciation on Jameson Land, central East Greenland, and still there is debate about whether the area was: (i) ice-free, (ii) covered with a local non-erosive ice cap(s), or (iii) overridden by the Greenland Ice Sheet during the Last Glacial Maximum (LGM). Here, we use cosmogenic exposure ages from erratics to reconc
Environmental factors influencing growth of and exopolysaccharide formation by Pediococcus parvulus 2.6
Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells
MMP-26 mRNA and estrogen receptor alpha co-expression in normal and pathological endometrium
Vanin-1 T26I polymorphism, hypertension and cardiovascular events in two large urban-based prospective studies in Swedes.
Endometrial expression of the estrogen-sensitive genes MMP-26 and TIMP-4 is altered by a substitution protocol without down-regulation in IVF patients.
BACKGROUND: The aim of this study was to analyse the effects of an estradiol (E2)–progesterone substitution protocol on the endometrial expression of estrogen-sensitive genes during the peri-implantation period. METHODS: Peripheral blood and endometrial biopsies were obtained from 13 infertile women both in a natural cycle (NC), on days 5 and 7 after ovulation (NC5, NC7), and in an artificial (sub
Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 beta-(1,4)-Mannanases from Podospora anserina Reveal Differences upon Manno-oligosaccharide Catalysis
t(3;21)(q26;q22) with AML1 rearrangement in a de novo childhood acute monoblastic leukaemia
Epithelial expression of matrix metalloproteinase-26 is elevated at mid-cycle in the human endometrium
Eotaxin-3 (CCL26) exerts innate host defense activities that are modulated by mast cell proteases
BackgroundDuring bacterial infections of the airways, a Th1-profiled inflammation promotes the production of several host defense proteins and peptides with antibacterial activities including -defensins, ELR-negative CXC chemokines, and the cathelicidin LL-37. These are downregulated by Th2 cytokines of the allergic response. Instead, the eosinophil-recruiting chemokines eotaxin-1/CCL11, eotaxin-2
