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Non-invasive pressure volume loops derived by cardiovascular magnetic resonance: association between area at risk or infarct size and cardiac hemodynamics at 2-6 days after myocardial infarction

BackgroundA novel non-invasive method for generation of pressure volume loops (PV-loops) using brachial blood pressure and cardiovascular magnetic resonance (CMR) imaging has recently been presented and validated (1). The non-invasive nature of this method enables calculation of PV-loops in large patient cohorts previously not feasible due to the need of invasive measurements.PurposeThe purpose of

Influence of the mannan binding module of beta-mannanase CfMan26A in the hydrolysis of mannan

Hemicellulose is next to cellulose the most abundant polysaccharide on earth and as such an important renewable resource. Mannans are the major hemicellulose in so:ftwodd and are found as storage polysaccharide in various plants. -mannanases are the main mannan degrading enzymes. In this work the -1,4-mannanase from the soilliving bacteria Cellulosamas Jimi was studied and special focus was put on

Cranked Nilsson-Strutinsky model applied to high spin states in Na22,23 : Systematics of rotational isomers and band terminations in the A=20-26 region

Previously proposed high spin states in Na22,23 are compared with calculations from the cranked Nilsson model including Strutinsky renormalization. High K rotational isomers are proposed for Iπ=6- in Na22 and 11/2+, 13/2+, and possibly 15/2+ in Na23. The positive parity yrast sequences in these two nuclei are analyzed in terms of the change from collective to single particle behavior at I=9 (22Na)

A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1

Genome-wide association studies (GWASs) have shown that common genetic variation contributes to the heritable risk of childhood acute lymphoblastic leukemia (ALL). To identify new susceptibility loci for the largest subtype of ALL, B-cell precursor ALL (BCP-ALL), we conducted a meta-analysis of two GWASs with imputation using 1000 Genomes and UK10K Project data as reference (totaling 1658 cases an