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Today’s global competition forces manufacturing companies to re-evaluate their existing processes, technologies, manufactured parts and services in order to focus on strategic activities. The question whether to make or to buy goods or services represents a problem faced by many companies when deciding between keeping technologies/processes in-house or purchasing them from an outside supplier. In
Hepatitis B virus (HBV) infection remains a major public health threat in the Middle East and North Africa (MENA). Phylogenetic analysis of HBV can be helpful to study the putative transmission links and patterns of inter-country spread of the virus. The objectives of the current study were to analyze the HBV genotype/sub-genotype (SGT) distribution, reverse transcriptase (RT), and surface (S) gen
Aims: (i) Determine whether between-observer reproducibility for Ki67 when assessed on whole sections according to a standardized scoring protocol is adequate for clinical application. (ii) Compare between-observer reproducibility of Ki67 scores assessed on hot-spots to scores using a global method that averages across a tissue section.Background: The nuclear proliferation biomarker Ki67 has multi
Denna doktorsavhandling undersöker samtal om personliga problem i mötet med en specialist i radio. I synnerhet handlar studien om den dynamiska process då förståelse skapas – när upplevelser av personliga bekymmer förklaras och definieras som problem av särskilda slag. Denna meningsskapande process undersöks i detalj så som den utspelar sig i dialoger i radio och mellan programdeltagare och radiolThe dissertation examines how personal troubles are talked about in an encounter with a professional on the public arena of radio broadcasting, where the professional has to meet the challenge of making professional advice not only useful for the person seeking help, but also relevant or interesting for the radio audience. The study explores the dynamic process of shaping an understanding of probl
Background: Olfaction and gustation underlie behaviors that are crucial for insect fitness, such as host and mate selection. The detection of semiochemicals is mediated via proteins from large and rapidly evolving chemosensory gene families; however, the links between a species' ecology and the diversification of these genes remain poorly understood. Hence, we annotated the chemosensory genes from
BACKGROUND AND PURPOSE: A new concept to increase return to work for patients listed as sick with chronic musculoskeletal pain has been used at a rehabilitation centre in Luleå, Sweden. The programme includes work for three days a week and intensive rehabilitation for two days a week, for 12 weeks, as a combination of 'on the job' training and rehabilitation after a period off work sick. The rehab
Preclinical studies suggest that stem cell therapy (SCT) may improve sensorimotor recovery after stroke. Upper extremity motor impairment (UEMI) is common after stroke, often entailing substantial disability. To evaluate the feasibility of post-stroke UEMI as a target for SCT, we examined a selected sample of stroke patients potentially suitable for SCT, aiming to assess the frequency and recovery
Genom digitaliseringen har nya skapandeformer introducerats. Sampling är en teknik som innebär att på musikområdet använda, spela in eller kopiera delar av verk för att använda dessa inslag i nya sammanhang. Denna skapandeform väcker intressanta frågeställningar om under vilka omständigheter ett sådant vidareutnyttjande kräver tillstånd från rättighetsägaren. Frågan är mer komplex än vad som kan uThrough the digitalization, new ways of creating music have been introduced. Sampling is one technique where parts of a musical work is used, taped or copied in order to be applied into new contexts. This method give rise to several interesting questions concerning under what circumstances such use demands a permission from the copyright owner. This specific issue is far more complex than one coul
Thesis Purpose: This study explores the major drivers and barriers to eco-innovation in Scandinavian and Finnish furniture companies, examining the influence of company size and age. The findings benefit stakeholders including businesses, policymakers, professionals, investors, and consumers. Theoretical Perspective: This study’s theoretical framework was developed through an exploration of eco-in
På Siciliens östkust strax söder om Syrakusa, ligger ett långsmalt naturområde som följer kusten längs halvön Maddalenas sydspets ut till udden Capo Murro di Porco. Det är en obebyggd kustremsa sånär som på en fyrbyggnad med två angränsande stenhus. Naturen domineras av det klippiga landskapet och de tre byggnaderna som kommit att smälta in i omgivningen. I detta arbete, som är en fallstudie som Capo Murro di Porco is situated in a narrow natural area that runs along the coast of the peninsula of Maddalena, just south of Syracuse on the east coast of Sicily. It is an area of stunning nature with dramatic topography, steep cliff sides and sparse vegetation. On the very line marking the transition from low vegetation to bare rock on the horn of the peninsula, a lighthouse and two rugged low
En följd av den nya lagen (2014:307) om straff för penningtvättsbrott har varit att ett flertal myndigheter, i diverse rapporter, riktat kritik mot att det råder brist på rättspraxis avseende straffvärdebedömningar i mål om penningtvättsbrott. Utöver dessa myndighetspublikationer är litteraturen om den straffrättsliga regleringen av penningtvättsbrott knapphändig. Det har därför varit av intresse The novel Act regarding penalties for money laundering offences (2014:307) has been criticized by a number of authorities. This, due to the fact that judicial precedent about penal assessment in cases of money laundering offence is scarce. Furthermore, there is a lack of evidence in the literature concerning the new legislation. Therefore, it has been interesting as a part of my essay to study how
Bakgrund: Obesitas och psykisk ohälsa tillhör de största globala hälsoutmaningarna i modern tid och har under de senaste decennierna varit ett växande problem. Människor har fått en mer stillasittande livsstil och större tillgång på kaloririk föda. Faktorerna som påverkar prevalensen är många men att det behöver ske en förändring är säkert. Syfte och frågeställningar: Syftet var att kartlägga BMI,
Integration management in Finland and Tampere is broad task including multiple actors and departments. To manage integration, is to coordinate the cross organizational cooperation of multiple service structures that support migrants with different kinds of services. Although integration work has traditionally been provided through the Employment & growth services,the other relevant services fo
Alla naturligt förekommande grundämnen, med få undantag, har skapats i stjärnors inre. Några av dem har skapats långsamt och kontinuerligt och stora mängder har ansamlats under årmiljonerna. Andra har skapats under några få sekunder i några av de mest våldsamma explosionerna i universum, nämligen de s.k. supernovorna. Genom att studera dessa processers avtryck, kan vi fördjupa vår kunskap om, t.exSulphur is one of the more interesting chemical elements from a scientific perspective. As a volatile element, sulphur could potentially be used as a tracer of galactic properties, such as star-formation rate and initial mass function, in both the Milky Way and beyond. But first its origin and production has to be understood. Knowledge of Galactic chemical evolution of sulphur is therefore vital.
The NPM is considered as an efficacious way to improve effectiveness and efficiency in management control of public health for its market-driven and market-driving characteristics. Theoretically, it is a hybrid of economics and business management in public management. Because of its advanced adaptability and flexibility, the NPM has been widely applied to many fields and yield results. In China’s
On July 8, 2013, the United States and the European Union started negotiations for the Transatlantic Trade and Investment Partnership (TTIP). The TTIP is a proposed international trade and investment agreement (IIA) that aims to create the largest free trade area in the world. Despite the promises of the TTIP, including job opportunities and economic gains of over €100 billion in the EU alone, the
The commercial availability of low-cost millimeterwave (mmWave) communication and radar devices is starting to improve the adoption of such technologies in consumer markets, paving the way for large-scale and dense deployments in fifthgeneration (5G)-and-beyond as well as 6G networks. At the same time, pervasive mmWave access will enable device localization and device-free sensing with unprecedent
Advances in understanding how cancer cells interact with the immune system allowed the development of immunotherapeutic strategies, harnessing patients’ immune system to fight cancer. Dendritic cell-based vaccines are being explored to reactivate anti-tumor adaptive immunity. Immune checkpoint inhibitors and chimeric antigen receptor T-cells (CAR T) were however the main approaches that catapulted
Background: Dexmedetomidine is a selective alpha-2 agonist with minimal impact on the haemodynamic profile. It is thought to be safer than morphine or stronger opioids, which are drugs currently used for analgesia and sedation in newborn infants. Dexmedetomidine is increasingly being used in children and infants despite not being licenced for analgesia in this group. Objectives: To determine the o
